initial — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T19125	3-Phenylbutyric acid		Others , Endogenous Metabolite
	3-Phenylbutyric acid undergoes metabolism through initial oxidation processes involving both its benzene ring and side chain. It serves as an effective agent for the isolation of Rhodococcus rhodochrous PB1 from compost ...		Others , Endogenous Metabolite
T16335	Nonaethylene glycol monododecyl ether	Nonaoxyethylene monododecyl ether,Polidocanol	Others
	Nonaethylene glycol monododecyl ether (Polidocanol) is a nonionic surfactant and polyethylene glycol (PEG) detergent. It can be used to form initial coalesced O/W emulsion droplets and for protein separation and purifica...		Others
T0765	Fomepizole	Antizol-Vet,4-Methylpyrazole,Antizol	P450 , CAT , AChR
	Fomepizole (4-Methylpyrazole) is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole(4-Methylpyrazole) is a competitive inhibitor of alcohol dehydrogenase, the enzyme that cata...		P450 , CAT , AChR
T2283	PX-12	IV-2,PX12	Thioredoxin
	PX-12 (PX12) (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits tumor gr...		Thioredoxin
T4776	Glycerol	Glycerin	Endogenous Metabolite
	Glycerol or glycerin is a colourless, odourless, viscous liquid that is sweet-tasting and mostly non-toxic. It is widely used in the food industry as a sweetener and humectant and in pharmaceutical formulations. Glycerol...		Endogenous Metabolite
T5189L	Omadacycline mesylate	PTK 0796,PTK-0796,PTK0796
	Omadacycline is an aminomethylcycline antibiotic. Omadacycline demonstrated net cidal activity in relation to the initial burden against four strains of Streptococcus pneumoniae.
T28823	SNAP-7941	SNAP7941
	SNAP-7941 is a selective antagonist of the melanin concentrating hormone receptor MCH1 with promising anxiolytic, antidepressant and anorectic effects in initial animal studies.
T39054	Furosine dihydrochloride
	Furosine dihydrochloride, an amino acid derivative, is a significant biochemical indicator of initial Maillard reactions. The compound is strongly associated with various diseases, including diabetes.
T40924	Tellimagrandin II	Eugeniin
	Tellimagrandin II (Eugeniin) is the initial intermediate in the 4 C 1 -glucose derived series of ellagitannins. Additionally, it possesses the ability to inhibit antibiotic resistance exhibited by drug-resistant Staphylo...
T15499	HOOCCH2O-PEG4-CH2COOH		Others
	HOOCCH2O-PEG4-CH2COOH (compound 5), is a symmetric polyethylene glycol (PEG) linker. It is primarily utilized in the synthesis of the initial Homo-PROTAC[1] compound.		Others
T36686	Ac-Arg-Gly-Lys(Ac)-AMC
	Ac-RGK(Ac)-AMC, fluorogenic substrate for assaying histone deacetylase (HDAC) activity in a two-step enzymatic reaction. The assay consists of the initial lysine deacetylation by HDAC followed by the release of the fluor...
T73216	Gepefrine
	Gepefrine, an orally active pressor and sympathomimetic agent, enhances the initial orthostatic regulation of arterial pressure.
T70316	AZD6642
	AZD6642 is a potential and selective 5-Lipoxygenase activating Protein (FLAP) inhibitor. AZD6642 shows high specific potency and low lipophilicity resulting in a selective and metabolically stable profile. Based on initi...
T40932	Benzylacyclouridine	5-Benzylacyclouridine,BAU
	Benzylacyclouridine (BAU) is a powerful and selective inhibitor of uridine phosphorylase, the initial enzyme involved in uridine catabolism. Additionally, it can regulate the cytotoxic adverse effects of 5-fluorouracil (...
T2S2363	Corydine		IL Receptor , Antifection
	Corydine is the adrenolytic and weak cholinergic agent, it shows antimicrobial, and antineoplastic activities. Corydine shows irritant and respiratory stimulant and CNS depressant activities. Injected intravenously in ra...		IL Receptor , Antifection
T81413	PppApG
	pppApG serves as an initial substrate for the synthesis of vRNA (viral RNA) and cRNA (complementary RNA), with applications in influenza virus research [1].
T37990	15-keto Prostaglandin F1α	15-keto Prostaglandin F1α
	15-keto PGF1α is the initial metabolite of PGF1α via 15-hydroxy PGDH. In mammals, oxidation of C-15 markedly attenuates receptor binding and activity. In fish, the 15-keto compounds serve as post-ovulatory pheromones and...
T23654	Afeletecan free base	BAY 56-3722,BAY56-3722,BAY-563722,Afeletecan
	Afeletecan is a water-soluble camptothecin derivative. Afeletecan stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex. Both the initial cleavage reaction and religation steps ...
T71147	PBS-1086
	PBS-1086 is a novel dual inhibitor of the canonical and noncanonical NF-κB pathways, increasing the magnitude and duration of initial EGFR inhibitor response in multiple NSCLC models, decreasing PDHK1 expression, and sup...
T76064	Beta-defensin 103 isoform X1, pig
	Beta-defensin 103 isoform X1, pig, is an antimicrobial peptide prevalent in various organisms, playing a crucial role in the initial defense strategy of their innate immune system against pathogens [1].