Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Tag
  • C-His
    (1)
  • C-His-Avi
    (1)
  • C-hFc-Avi
    (1)
  • C-mFc
    (1)
  • N-6xHis
    (1)
  • N-GST
    (1)
  • N-His
    (1)
  • Tag Free
    (4)
TargetMol | Tags By Expression System
  • E. coli
    (6)
  • HEK293 Cells
    (5)
TargetMol | Tags By Species
  • Canine
    (1)
  • Cynomolgus
    (2)
  • Human
    (4)
  • Mouse
    (2)
  • Rhesus
    (1)
  • Sus scrofa (Pig)
    (1)
Filter
Search Result
Results for "

il 33

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    9
    TargetMol | Activity
  • Peptide Products
    1
    TargetMol | inventory
  • Inhibitory Antibodies
    4
    TargetMol | natural
  • Recombinant Protein
    15
    TargetMol | composition
TargetMolTargetMolCompare
IL-33 Protein, Pig, Recombinant (GST)
TMPH-03115
IL-33 Protein, Pig, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 44.6 kDa and the accession number is M5B263.
  • $360
20 days
Size
QTY
TargetMolTargetMolCompare
IL-33 Protein, Human, Recombinant
TMPY-00861
IL-33 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is O95760-1.
  • $57
In Stock
Size
QTY
TargetMolTargetMolCompare
IL-33 Protein, Cynomolgus, Recombinant
TMPY-05449
IL-33 Protein, Cynomolgus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18.1 kDa and the accession number is A0A2K5W3I1.
  • $177
In Stock
Size
QTY
TargetMolTargetMolCompare
IL-33 Protein, Cynomolgus, Recombinant (His)
TMPK-00163
Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellular nucleus in several tissues. High levels of IL-33 are expressed in epithelial barrier tissues and endothelial barriers. ST2 is a receptor for IL-33, expressed selectively on a subset of Th2 cells, mediating some of their functions.
  • $534
7-10 days
Size
QTY
TargetMolTargetMolCompare
IL-33 Protein, Mouse, Recombinant
TMPJ-01210
Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identified based on sequence and structural homology with IL-1 family cytokines. It is up‑regulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1 alpha or IL‑1 beta stimulation. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1. BindingIL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces the expression of IL-4, IL-5, IL-13 and also leads to severe pathological changes in mucosal organs.
  • $83
In Stock
Size
QTY
TargetMolTargetMolCompare
IL-33 Protein, Rhesus macaque, Recombinant (His)
TMPJ-00617
Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1 ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.
  • $184
7-10 days
Size
QTY
TargetMolTargetMolCompare
IL-33 Protein, Canine, Recombinant
TMPY-02789
IL-33 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.8 kDa and the accession number is O97863.
  • $177
In Stock
Size
QTY
TargetMolTargetMolCompare
IL-17RA Protein, Human, Recombinant (aa 33-320, hFc & Avi), Biotinylated
TMPK-00405
Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restricted to activated T cells, the IL‑17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL‑17 R gene was localized to chromosome 22.
  • $814
7-10 days
Size
QTY
TargetMolTargetMolCompare
Siglec-8 Protein, Human, Recombinant (mFc)
TMPJ-01361
Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Siglec-8 is expressed on eosinophils, basophils, and mast cells, and it shows a binding preference for the carbohydrate 6-O sulfated sLex. At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney. Mature human Siglec-8 consists of a 347 amino acid (aa) extracellular domain (ECD) with three Ig-like domains, a 21 aa transmembrane segment, and a 115 aa cytoplasmic domain with two tyrosine based signaling motifs. Alternative splicing generates additional isoforms that either lack most of the second Ig-like domain or have a substituted cytoplasmic domain without the signaling motifs. Cross-linking of Siglec-8 inhibits Fc epsilon RI alpha induced mast cell degranulation. It also induces eosinophil apoptosis, an effect which is enhanced by the eosinophil-activating cytokines IL-5, IL-33, and GM-CSF.
  • $86
7-10 days
Size
QTY
TargetMolTargetMolCompare
IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (aa 21-367, His)
TMPK-01029
Interleukin (IL)-1R3 is the co-receptor in three signaling pathways that involve six cytokines of the IL-1 family (IL-1α, IL-1β, IL-33, IL-36α, IL-36β and IL-36γ). In many diseases, multiple cytokines contribute to disease pathogenesis. For example, in asthma, both IL-33 and IL-1 are of major importance, as are IL-36 and IL-1 in psoriasis.
  • $255
7-10 days
Size
QTY
TargetMolTargetMolCompare
CD93/C1qR1 Protein, Human, Recombinant (His&Avi), Biotinylated
TMPK-01202
CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM-induced asthma mice showed significant airway hyperresponsiveness and inflammation with Th2 cytokine activation, along with decreased CD93 expression in bronchial epithelial cells and lung homogenates but increased serum CD93 levels.
  • $814
7-10 days
Size
QTY
TargetMolTargetMolCompare
CD20 Protein, Human, Recombinant (aa 213-297, His)
TMPY-02819
CD20 Protein, Human, Recombinant (aa 213-297, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 12.1 kDa and the accession number is A0A024R507.
  • $357
7-10 days
Size
QTY
TargetMolTargetMolCompare
CD20 Protein, Human, Recombinant (His & Avi)
TMPK-00183
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases. CD20 Protein, Human, Recombinant (His & Avi) is expressed in E. coli expression system with C-His-Avi tag. The predicted molecular weight is 16.8 kDa and the accession number is P11836-1.
  • $465
7-10 days
Size
QTY
TargetMolTargetMolCompare
CD20 Protein, Human, Recombinant (TrxA)
TMPY-04615
CD20 Protein, Human, Recombinant (TrxA) is expressed in E. coli expression system with TrxA tag. The predicted molecular weight is 23.9 kDa and the accession number is A0A024R507.
  • $700
7-10 days
Size
QTY
TargetMolTargetMolCompare
CD20 Protein, Human, Recombinant (TrxA), Biotinylated
TMPY-05271
CD20 Protein, Human, Recombinant (TrxA), Biotinylated is expressed in E. coli expression system with TrxA tag. The predicted molecular weight is 23.9 kDa and the accession number is A0A024R507.
  • $245
In Stock
Size
QTY