d44

D44 is a Plasmodium FKBPs inhibitor.

CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe.

The Anti-CD44 Antibody (Hermes-1) is a chimeric rat-derived IgG2a, κ antibody targeting human CD44. The isotype control for the Anti-CD44 Antibody (Hermes-1) is RatIgG2akappa, Isotype Control.

JPD447 is a MAC-0547630 derivative that potentiates UppS inhibitors of β-lactam antibiotics with antimicrobial activity and can be used to study bacterial infections.

Anti-Mouse CD11a Antibody is a rat-derived IgG2b inhibitor specific to the mouse CD11a molecule.

Antitumor Agent-108 (Compound 5), an inhibitor of the Hyaluronic Acid (HA)-CD44 interaction, effectively disrupts cancer spheroid integrity and exhibits antiproliferative activity against cancer cells [1].

HA-CD44 interaction inhibitor 3 (compound 5d) is an inhibitor of the Hyaluronic acid (HA)-CD44 interaction. It has inhibitory effects on MDA-MB-231 (CD44++) cells and MCF-7 (CD44--) cells with EC50 values of 4.24 μM and 14.74 μM, respectively. HA-CD44 interaction inhibitor 3 is applicable to cancer research.

FD44 is an inhibitor of the NCS-1 Ric8a interaction.

Anti-Mouse CD44 Antibody (IM7) is a monoclonal antibody targeting CD44 in mice.

NPD4456 (Compound 3) is a 3-phenylcoumarin Vpr inhibitor. It binds competitively to Vpr and inhibits HIV-1 virus infection.

D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).

Antitumor agent-109 (compound 6) is a dual-function inhibitor targeting hyaluronic acid and CD44, molecules implicated in tumor progression and invasion, and exhibits potent antitumor activity by inhibiting MDA-MB-231 cells with an EC50 of 0.59 µM [1].