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Anti-PCNA Monoclonal Antibody (6D447)
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Catalog No. TMAT-0817 Copy Product Info
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Anti-PCNA Monoclonal Antibody (6D447) is a Mouse antibody targeting PCNA. Anti-PCNA Monoclonal Antibody (6D447) can be used in WB,IHC,FCM.
Anti-PCNA Monoclonal Antibody
(6D447)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-PCNA Monoclonal Antibody (6D447) is a Mouse antibody targeting PCNA. Anti-PCNA Monoclonal Antibody (6D447) can be used in WB,IHC,FCM. |
| Ig Type | IgG1 |
| Clone | 6D447 |
| Reactivity | Human,Mouse,Rat,Rabbit,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/100-1/500; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PCNA (AA: 53-196 ) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PCNA |
| Gene ID | |
| Protein Name | DNA sliding clamp PCNA |
| Uniprot ID |
| Molecular Weight | Theoretical: 28.7 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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