complement c3

Expression system: E. coli
Length: 747-953, Partial
Activity: Not Tested

Expression system: E. coli
Length: 1321-1663, Partial
Activity: Not Tested

Complement C3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 186.43 kDa and the accession number is P01024.

Complement C3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 186.40 kDa and the accession number is XP_005587776.1.

Complement C3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.34 kDa and the accession number is NP_033908.2.

Complement C3 Protein, Mouse, Recombinant (aa 25-1663, His) is expressed in HEK293 Cells. The accession number is P01027-1.

Complement C3a Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9 KDa and the accession number is P01027.

Complement C3a Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13 KDa and the accession number is P01024.

Expression system: E. coli
Length: 193-510, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 1454-1744, Partial
Activity: Not Tested

Expression system: E. coli
Length: 1448-1738, Partial
Activity: Not Tested

Expression system: E. coli
Length: 23-761, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 23-464, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 23-464, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 42-319, Partial
Activity: Not Tested

Expression system: E. coli
Length: 733-984, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 26-263, Full Length of Mature Protein
Activity: Not Tested

Expression system: P. pastoris (Yeast)
Length: 26-263, Full Length of Mature Protein
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 20-685, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 32-116, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 17-279, Partial
Activity: Not Tested

Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3, which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the regulation of systemic energy balance and physiologic and pathologic processes, including immunity and inflammation.

Complement Factor H (CFH) is a secreted protein which is a member of the regulators of complement activation family and is a complement control protein. It is expressed by the liver and secreted in plasma. Its principal function is to regulate the Alternative Pathway of the complement system, ensuring that the complement system is directed towards pathogens or other dangerous material and does not damage host tissue. Factor H regulates complement activation on self cells and surfaces by possessing both cofactor activity for the Factor I mediated C3b cleavage, and decay accelerating activity against the alternative pathway C3-convertase, C3bBb. Factor H exerts its protective action on self cells and self surfaces but not on the surfaces of bacteria or viruses, because it binds to glycosaminoglycans (GAGs) that are generally present on host cells but not, normally, on pathogen surfaces.

Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D CFD Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 52.2 kDa and the accession number is P03953-1.