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Search Result

Search Results for " bop "

Targets

Thrombopoietin Receptor

35

Compounds

2

Natural Products

6

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T26887 BOP
BOP is anantagonist of alpha4beta1/alpha9beta1 integrins. BOP rapidly mobilizes long-term multi-lineage reconstituting hematopoietic stem cells (HSC).
T41149 BOP-JF549 BOP-JF549
BOP-JF549 is a fluorescent dual α9β1/α4β1 integrin inhibitor. Comprises BOP conjugated to Janelia Fluor® 549. Fluorogenic: fluoresces only once bound to integrins, enabling hassle-free no-wash experiments. Bright and pho...
T41153 BOP-JF646 BOP-JF646
BOP-JF646 is a fluorescent dual α9β1/α4β1 integrin inhibitor. Comprises BOP conjugated to Janelia Fluor®646. Fluorogenic: fluoresces only once bound to integrins, enabling hassle-free no-wash experiments. Bright and phot...
T26888 BOP sodium BOP sodium salt
BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.
T35585 I-BOP
I-BOP is an agonist (KD=0.61 nM) at the thromboxane A2 receptor (TP). I-BOP promotes cell proliferation by activating the PI3K pathway in vascular smooth muscle.
T12285 Ebopiprant OBE022,OBE-022 Others
Ebopiprant (OBE022) is an orally available, selective and potent prostaglandin F2α (PGF2α) receptor antagonist that interferes with the binding of PGF0126α to the FPR and can be used in the study of obesity.
T34905 Totrombopag SB559448,SB 559448,SB-559448,LGD-4665,Synonym 2,LGD 4665,LGD4665
Totrombopag (SB559448) is a candidate compound for action on RSV polymerase.
TQ0223 Lusutrombopag S-888711,Mulpleta Thrombin , Thrombopoietin Receptor
Lusutrombopag (Mulpleta) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery.
T13098 TBOPP Others
TBOPP is a selective DOCK1 inhibitor (IC50 : 8.4 μM), with anti-tumor activity for broader types of tumors.
T1058 Carboplatin NSC 241240,CBDCA,JM-8 DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Autophagy
Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor. Carboplatin binds to DNA, inhibits replication and transcription, and induces cell death. Carboplatin has antitumor activity.
T7569 Clebopride malate Dopamine Receptor
Clebopride malate is a dopamine antagonist drug Used to treat functional gastrointestinal disorders such as nausea or vomiting.
T6825 Eltrombopag Olamine Promacta Olamine,Revolade,Eltrombopag diethanolamine salt,SB497115,SB-497115GR Thrombin
Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrom...
T22285 Carboprost 15(S)-15-Methyl Prostaglandin F2α,15-Methyl-PGF2α Prostaglandin Receptor
Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a synthetic prostaglandin analogue of PGF2α which has the effect of oxytocic. Carboprost is commonly used to restore uterine tone.
T17018 TCPOBOP BCL
TCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly. TCPOBOP decreases Fas-induced murine liver injury by altering Bcl-2 proteins.
T3187 Fluoroclebopride Dopamine Receptor
Fluoroclebopride is a dopamine (DA) D2 receptor ligand.
T2562 Eltrombopag SB-497115,SB-497115-GR Thrombin
Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet thrombopoietin receptor (TPO-R or CD110).
T7417 Avatrombopag YM477,AKR-501,E5501 Thrombin , Thrombopoietin Receptor
Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platelet production.
T40654 Avatrombopag hydrochloride AKR-501 hydrochloride,YM477hydrochloride,E5501hydrochloride
Avatrombopag hydrochloride (AKR-501) is an orally active, nonpeptide agonist of the thrombopoietin (TPO) receptor with an EC 50 of 3.3 nM. It effectively mimics the biological activities of TPO, stimulating platelet prod...
T63356 Bopindolol fumarate
Bopindolol ((±)-Bopindolol) fumarate is an orally active β-adrenoceptor (ARs) antagonist with partial agonist activity that is non-selective for β1- and β2-ARs and has low affinity for the β3-AR subtype. Bopindolol fumar...
T9451 Bopindolol
Bopindolol is an orally active antagonist of β-adrenoceptors (ARs) with partial agonist activity. Bopindolol is non-selective for β1- and β2-ARs and has low affinity for β3-AR subtype. Bopindolol is a prodrug of pindolol...
T68560 Totrombopag choline
Totrombopag, also known LGD-4665, GSK2285921 and SB559448, is an oral thromobopoietin receptor agonist, is being developed as a new generation small molecule thrombopoietin (TPO) mimetic. It is a highly selective and po...
T34637 Sibopirdine X9121,EXP921
Sibopirdine is a new type of cognitive enhancer and intelligence booster that has been studied as a cognitive enhancer for the treatment of Alzheimer's disease.
T70000 Ebopiprant HCl
Ebopiprant, also known as OBE-022, is an Oral and Selective Prostaglandin F 2α Receptor Antagonist as an Effective and Safe Modality for the Treatment of Preterm Labor. OBE022 exhibits potent tocolytic effects on human ...
T27536 Hetrombopag olamine
Hetrombopag olamine is a non-peptide thrombopoietin (TPO) receptor agonist with oral activity.
T38602 (E/Z)-Eltrombopag 13C4 (E/Z)-Eltrombopag 13C4,(E/Z)-SB-497115 13C4
(E/Z)-Eltrombopag 13C4 ((E/Z)-SB-497115 13C4) is a mixture complex of E-Eltrombopag and Z-Eltrombopag, with 13C labeled. Z-Eltrombopag is a thrombopoietin (TPO) receptor agonist developed for certain conditions that lead...
T7569L Clebopride
Clebopride is antidopaminergic. Clebopride also has an effect of antiemetic.
T72265 Eltrombopag methyl ester
Eltrombopag Methyl Ester, a derivative of Eltrombopag, functions as a thrombopoietin (Tpo) receptor agonist to enhance platelet production and is employed in the study of certain thrombocytopenia variants.
T62865 Rafutrombopag
Rafutrombopag is a thrombopoietin (TPO) agonist.
T62864 Hetrombopag
Hetrombopag is a potent agonist of the thrombopoietin receptor. Hetrombopag is well tolerated and has a controlled safety profile. hetrombopag has potential for studies in immune thrombocytopenia.
T35871 Bopindolol (malonate)
Bopindolol is a non-selective β-adrenergic receptor antagonist. In vivo, bopindolol decreases heart rate and blood pressure and attenuates ischemia-induced myocardial acidosis in dogs. Formulations containing bopindolol ...
T68888 Avatrombopag maleate
Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis througho...
TMIH-0102 Avatrombopag-d8
Avatrombopag-d8 is a deuterated compound of Avatrombopag. Avatrombopag has a CAS number of 570406-98-3. Avatrombopag is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocy...
T41152 R-BC154 R-BC154
R-BC154 is a high affinity fluorescent α4β1/α9β1 inhibitor (Kdvalues are 12.7 and 38 nM, respectively); fluorescent version of BOP. Rapidly and preferentially mobilizes HSCs and progenitorsin vivo. Excitation maximum, 56...
T36160 8-iso Prostaglandin E2 8-iso Prostaglandin E2
8-iso PGE2 is one of several isoprostanes produced from arachidonic acid during lipid peroxidation. It is a potent renal vasoconstrictor in the rat. 8-iso PGE2 inhibits U-46619 or I-BOP-induced platelet aggregation with ...
T80224 Bid BH3 (80-99)
Bid BH3 (80-99) is a biologically active peptide known as a pro-apoptotic member of the 'BH3-only' (BOPS) subset within the BCL-2 protein family, pivotal in apoptosis regulation. It notably interacts with Bcl-2, Bax, and...

Compounds

BOP
T26887
Synonym:
Target:
BOP-JF549
T41149
Synonym: BOP-JF549
Target:
BOP-JF646
T41153
Synonym: BOP-JF646
Target:
BOP sodium
T26888
Synonym: BOP sodium salt
Target:
I-BOP
T35585
Synonym:
Target:
Ebopiprant
T12285
Synonym: OBE022,OBE-022
Target: Others
Totrombopag
T34905
Synonym: SB559448,SB 559448,SB-559448,LGD-4665,Synonym 2,LGD 4665,LGD4665
Target:
Lusutrombopag
TQ0223
Synonym: S-888711,Mulpleta
Target: Thrombin, Thrombopoietin Receptor
TBOPP
T13098
Synonym:
Target: Others
Carboplatin
T1058
Synonym: NSC 241240,CBDCA,JM-8
Target: DNA Alkylator/Crosslinker, DNA/RNA Synthesis, Autophagy
Clebopride malate
T7569
Synonym:
Target: Dopamine Receptor
Eltrombopag Olamine
T6825
Synonym: Promacta Olamine,Revolade,Eltrombopag diethanolamine salt,SB497115,SB-497115GR
Target: Thrombin
Carboprost
T22285
Synonym: 15(S)-15-Methyl Prostaglandin F2α,15-Methyl-PGF2α
Target: Prostaglandin Receptor
TCPOBOP
T17018
Synonym:
Target: BCL
Fluoroclebopride
T3187
Synonym:
Target: Dopamine Receptor
Eltrombopag
T2562
Synonym: SB-497115,SB-497115-GR
Target: Thrombin
Avatrombopag
T7417
Synonym: YM477,AKR-501,E5501
Target: Thrombin, Thrombopoietin Receptor
Avatrombopag hydrochloride
T40654
Synonym: AKR-501 hydrochloride,YM477hydrochloride,E5501hydrochloride
Target:
Bopindolol fumarate
T63356
Synonym:
Target:
Bopindolol
T9451
Synonym:
Target:
Totrombopag choline
T68560
Synonym:
Target:
Sibopirdine
T34637
Synonym: X9121,EXP921
Target:
Ebopiprant HCl
T70000
Synonym:
Target:
Hetrombopag olamine
T27536
Synonym:
Target:
(E/Z)-Eltrombopag 13C4
T38602
Synonym: (E/Z)-Eltrombopag 13C4,(E/Z)-SB-497115 13C4
Target:
Clebopride
T7569L
Synonym:
Target:
Eltrombopag methyl ester
T72265
Synonym:
Target:
Rafutrombopag
T62865
Synonym:
Target:
Hetrombopag
T62864
Synonym:
Target:
Bopindolol (malonate)
T35871
Synonym:
Target:
Avatrombopag maleate
T68888
Synonym:
Target:
Avatrombopag-d8
TMIH-0102
Synonym:
Target:
R-BC154
T41152
Synonym: R-BC154
Target:
8-iso Prostaglandin E2
T36160
Synonym: 8-iso Prostaglandin E2
Target:
Bid BH3 (80-99)
T80224
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T14865 Carboprost tromethamine Prostaglandin Receptor
Carboprost tromethamine, a synthetic 15-methyl analogue of prostaglandin F2α, effectively promotes uterine contractions and significantly reduces bleeding during and post-delivery.
TN4394 Kobophenol A MMP , BCL , p38 MAPK , NF-κB , ROS , DNA/RNA Synthesis , CDK , JNK
Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell death. Kobophenol A inhibits AChE activity in a dose-depen...

Natural Products

Carboprost tromethamine
T14865
Synonym:
Target: Prostaglandin Receptor
Kobophenol A
TN4394
Synonym:
Target: MMP, BCL, p38 MAPK, NF-κB, ROS, DNA/RNA Synthesis, CDK, JNK

Recombinant Proteins

Species：
Human (3)
Cynomolgus (1)
Halobacterium halobium (1)
Mouse (1)
Expression System：
HEK293 Cells (5)
E. coli (1)
Tag：
C-His (2)
C-hFc (2)
N-10xHis-SUMO, C-Myc (1)
N-His (1)
Cat No. Product Name Species Expression System
TMPH-00785 Bacteriorhodopsin Protein, Halobacterium halobium, Recombinant (His & Myc & SUMO) Halobacterium halobium E. coli
Light-driven proton pump.
TMPY-00939 Thrombopoietin Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Thrombopoietin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37 kDa and the accession number is P40226-1.
TMPY-01609 Thrombopoietin Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Thrombopoietin Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.8 kDa and the accession number is XP_005546625.1.
TMPY-04201 Thrombopoietin Protein, Human, Recombinant (hFc) Human HEK293 Cells
Thrombopoietin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45 kDa and the accession number is P40225-1.
TMPY-00164 Ribophorin II Protein, Human, Recombinant (His) Human HEK293 Cells
Ribophorin II Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.4 kDa and the accession number is P04844-1.
TMPY-00157 Ribophorin II Protein, Human, Recombinant (hFc) Human HEK293 Cells
Ribophorin II Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84 kDa and the accession number is P04844-1.
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