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Search Results for " mhc "

Targets

51

Compounds

3

Natural Products

438

Recombinant Proteins

Cat No. Product Name Synonyms Targets
TP2270 MHC class II antigen (45-57) [Homo sapiens] Others
MHC class II antigen (45-57) [Homo sapiens] is a peptide with the sequence H2N-Asp-Leu-Asp-Lys-Lys-Glu-Thr-Val-Trp-His-Leu-Glu- Glu-OH, MW= 1868.07. MHC (major histocompatibility complex) class II molecules are found onl...
T2161 Cardiogenol C Wnt/beta-catenin
Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.
T8005 Cardiogenol C hydrochloride Cardiogenol C HCl,Cardiogenol C Wnt/beta-catenin
Cardiogenol C hydrochloride (Cardiogenol C) can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).
T40898 DMHCA
DMHCA, a potent, selective LXR agonist, specifically activates the LXR pathway's cholesterol efflux arm, avoiding triglyceride synthesis stimulation. This compound exhibits anti-inflammatory properties and is utilized in...
TP2502 KYGVSVQDI Acetate Others
KYGVSVQDI Acetate is the DNA sequence encoding the MHC class I-restricted peptide p60(217-225) from Listeria monocytogenes.
TP1591L OVA G4 peptide acetate(148274-82-2 free base) SIIGFEKL acetate Others
OVA G4 peptide acetate(148274-82-2 free base) (SIIGFEKL acetate) is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope of ovalbumin presented by...
TP1777L P2Ca acetate(142606-55-1 free base) Others
p2Ca acetate is a naturally processed peptide that derives from a ubiquitous enzyme, alpha-ketoglutarate dehydrogenase, and is recognized in association with the class I MHC protein, Ld, by a CTL clone (2C).
TP1327L OVA Peptide 257-264 2TFA (138831-86-4 free base) OVA Peptide 257-264 2TFA 1262751-08-5(TFA-2TFA) Others
OVA Peptide 257-264 2TFA (138831-86-4 free base) is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.
T73133 FGF22-IN-1 Others
FGF22-IN-1 is a potential CD4 N-terminal immunoglobulin variable region-like domain (CD4 D1) inhibitor.FGF22-IN-1 inhibits the interaction between CD4 and major histocompatibility complex (MHC) class II proteins and supp...
TP1543L G280-9 acetate(156761-76-1 free base) Others
G280-9 acetate is a common melanoma gp100 epitope restricted by MHC-associated HLA-A2. The G280-9 sequence is unique because it could be recognized by cytotoxic T lymphocytes at very low concentrations, however it shows ...
T9901A-001 Relatlimab BMS-986016 Others
Relatlimab(BMS-986016) is a monoclonal antibody targeting human anti-LAG-3, generated by immunization of transgenic mice with human immunoglobulin carrying recombinant LAG-3 protein.Relatlimab has a blocking effect, bloc...
T12079 ML604440 Proteasome
ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.
TP2315 Glatiramer Acetate Others
Glatiramer acetate (GA) is a synthetic amino acid copolymer that is approved for treatment of relapsing remitting multiple sclerosis (RRMS) and clinically isolated syndrome (CIS).
TP2360 A2-Binding peptide
A2-Binding peptide has involved in the assembly of MHC Class I molecules.
T7619 OVA Peptide(257-264) OVA Peptide 257-264,OVA Peptide 257-264 (2TFA) Others
OVA Peptide(257-264) is an ovalbumin octamer Peptide expressed by class I MHC molecule h-2kb.
T83861 Bactobolamine
Bactobolamine, an immunosuppressant, suppresses IL-2 production in CTLL cells at a concentration of 200 µg/ml and extends heart allograft survival in both MHC-compatible and MHC-incompatible rat pairings at a dosage of 2...
T78247 Ieramilimab IMP701,LAG525
Ieramilimab (LAG525; IMP701) is a humanized IgG4 monoclonal antibody that targets LAG-3, disrupting its interaction with MHC-II molecules [1].
T39005 OVA (55-62)
OVA 55-62 is a truncated peptide derived from the ovalbumin (OVA) antigen, specifically designed to bind to the H2-Kb mouse major histocompatibility complex (MHC) class I molecule.
T81590 OVA peptide
Ovalbumin (OVA) peptide, primarily found in egg white, is a class I (Kb)-restricted peptide epitope presented by H-2Kb, the mouse MHC (major histocompatibility complex) class I gene product. It has garnered significant a...
TP1589 EGFRvIII peptide (PEPvIII) EGFRvIII peptide PEPvIII
PEPvIII, a peptide sequence from EGFRvIII, was designed to represent a target of glioma and is presented by MHC I/II complexes.
TP1327 OVA Peptide(257-264) TFA OVA Peptide (257-264) TFA
OVA Peptide (257-264) TFA, an octameric peptide epitope from ovalbumin, is presented by the class I MHC molecule, H-2Kb, showcasing a class I (Kb)-restricted profile.
T80907 TYVPANASL
TYVPANASL, a nine-amino-acid MHC I-binding epitope from HER2/neu for CD8 T cells, can be utilized in the development of J-LEAPS vaccines [1].
T76529 HBV Seq2 aa:28-39
HBV Seq2 aa:28-39, a Hepatitis B surface antigen (HBsAg) peptide, specifically binds to Major Histocompatibility Complex (MHC) class I molecules, as evidenced in sources [1] [2].
T36116 Concanamycin B
Concanamycin B is a macrolide antibiotic that selectively inhibits vacuolar type H+-ATPases, also known as V-ATPases (IC50 = 5 nM). In this way, it blocks the acidification of vacuolar organelles as well as early to late...
TP1126 InsB 9-23 Insulin B chain (9-23)
InsB (9-23) is an insulin B-chain peptide that binds to a class II histocompatibility complex (MHC) allele called I-Ag7.
T80906 TYVPANASL TFA
TYVPANASL TFA, a nine-amino-acid MHC I-binding CD8 T-cell epitope derived from HER2/neu, is utilized in the formulation of J-LEAPS vaccines [1].
T38794L LLO (91-99) acetate LLO (91-99) acetate(137856-41-8 free base) Others
LLO (91-99) acetate is an exotoxin and a class I MHC-restricted T-cell epitopes of listeriolysin. LLO (91-99) acetate is essential for the induction of T-cell mediated immunity in vivo.
TP1777 P2Ca
p2Ca, a naturally processed peptide that derives from a ubiquitous enzyme, alpha-ketoglutarate dehydrogenase, and is recognized in association with the class I MHC protein, Ld, by a CTL clone (2C).
T81790 Miptenalimab BI-754111
Miptenalimab (BI-754111) is an anti-human LAG-3 antibody with a dissociation constant (K D) of 88.6 nM for h LAG-3, effectively blocking the interaction between LAG-3 and its ligand MHC-II [1].
TP1652 OVA G4 peptide TFA (148274-82-2 free base) OVA G4 peptide TFA
OVA G4 peptide TFA (SIIGFEKL) is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope.
T82743 CFP10 (71–85)
CFP10 (71–85) is an immunologically active peptide that induces IFN-γ production and cytotoxic T lymphocyte (CTL) activity in CD4+ and CD8+ T cells from individuals with diverse MHC class II and I expression profiles.
T80857 VLHDDLLEA
VLHDDLLEA, a peptide extractable from the HLA-A*0201 MHC complex, is identifiable by HLA-A*0201-restricted cytotoxic T cells (CTLs). It serves as a research tool in studies of graft versus host disease (GvHD) [1].
T38794 LLO (91-99) LLO (91-99),Listeriolysin O (91-99)
LLO (91-99), also known as Listeriolysin O (91-99), is a class I MHC-restricted T-cell epitope derived from listeriolysin (LLO), an exotoxin. It plays a vital role as an antigen in the induction of T-cell mediated immuni...
T75982 LCMV gp33-41 TFA
LCMV gp33-41 (TFA), an 11-amino-acid carboxyl-extended peptide, comprises a lymphocytic choriomeningitis virus sequence that is presented by MHC class I H-2Db molecules to cytotoxic T lymphocytes [1].
T78332 Eftilagimod alfa IMP321,LAG-3Ig
Eftilagimod alfa (IMP321), a recombinant LAG-3Ig fusion protein, binds to MHC class II and mediates the activation of antigen-presenting cells (APCs), which in turn activates CD8 T-cells. It is utilized in the research o...
T82471 Encelimab
Encelimab, an anti-LAG3 antibody, inhibits the LAG-3/MHC II interaction to promote T-cell activation and, when used alone or alongside an anti-PD-1 antibody, shrinks tumors in a lymphoma mouse model (A20 cell xenograft) ...
TP1591 OVA G4 peptide
OVA G4 peptide (SIIGFEKL) is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope.
T40590 NY-ESO-1 (87-111)
NY-ESO-1 (87-111) is a pan-MHC class II-restricted peptide that interacts with various HLA-DR and HLA-DP4 molecules, inducing activation of CD4+ T cells with Th1-type and Th-2/Th0-type responses, when presented in conjun...
TP1502 MAGE-A3 (195-203) MAGE-A3 195-203
This peptide MAGE-3-encoded HLA-A24 epitope is a high MHC binder.The identification of this MAGE-3/HLA-A24 peptide may as a result effectiveially offer the opportunities to design peptide-based immunotherapeutic approach...
TP1629 LCMV gp33-41 (TFA) (151705-84-9 free base) LCMV gp33-41 (TFA)
LCMV gp33-41 (TFA), the carboxyl-extended 11-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes[1].
T40115 GAD65 (206-220) GAD65 (206-220)
GAD65 (206-220) is a synthetic peptide derived from glutamic acid decarboxylase (GAD) 65, specifically corresponding to residues 180-188. It is known that GAD65 interacts with I-Ag7 MHC class II molecules and is a signif...
T82414 Favezelimab MK-4280
Favezelimab (MK-4280) is a humanized anti-LAG-3 monoclonal antibody that inhibits the LAG-3/MHC class II interaction and shows potential for use in colorectal cancer (CRC) research, particularly when combined with the PD...
TP1758 LCMV gp33-41
LCMV gp33-41, the carboxyl-extended 11-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes.This is the H-2Db restricted ep...
T39311 Tyrosinase-related Protein 2 (TRP-2) (181-188)
Tyrosinase-related Protein 2 (TRP-2) (181-188) is a peptide derived from the tyrosinase-related protein 2 (TRP-2), specifically corresponding to residues 180-188. It is the primary epitope within TRP-2 that is recognized...
TP1543 G280-9
The G280-9 peptide, a common melanoma gp100 epitope restricted by MHC-associated HLA-A2. The G280-9 sequence is unique because it could be recognized by cytotoxic T lymphocytes at very low concentrations, however it show...
T81423 Polzastobart JTX 8064
Polzastobart (JTX-8064), a humanized IgG4 monoclonal antibody, functions as an antagonist selectively targeting LILRB2. It inhibits its interaction with both classical and non-classical MHC I molecules. By preventing LIL...
T76985 Tebotelimab
Tebotelimab (MGD-013) is a bispecific antibody targeting PD-1 and LAG-3, classified as a human IgG4κ dual-affinity re-targeting (DART) molecule. It exhibits binding affinities with EC50 values of 1.65 nM for PD-1 and 0.4...
TP1855 Moth Cytochrome C (MCC) (88-103) Moth Cytochrome C (MCC) 88-103
Moth Cytochrome C (MCC) (88-103), derived from the carboxyl terminus of moth cytochrome c, induces positive selection of TCR transgenic thymocytes.This peptide is derived from the carboxyl terminus of moth cytochrome c. ...
T83852 EGFRvIII Peptide TFA PEGFRvIII (9-mer),Epidermal Growth Factor Receptor Variant III Peptide
EGFRvIII peptide, a synthetic peptide mirroring the EGFRvIII fusion junction—a tumor-specific, perpetually active EGFR variant missing amino acids 6-273 of the wild-type—binds to HLA-A*0201-positive T2 cells under MHC cl...
T36984 Cyclic di-IMP (sodium salt)
Cyclic di-IMP (sodium salt) (c-di-IMP) is a synthetic second messenger structurally related to the bacterial second messengers cyclic di-GMP and cyclic di-AMP . C-di-IMP has adjuvant properties when co-administered with ...

Compounds

MHC class II antigen (45-57) [Homo sapiens]
TP2270
Synonym:
Target: Others
Cardiogenol C
T2161
Synonym:
Target: Wnt/beta-catenin
Cardiogenol C hydrochloride
T8005
Synonym: Cardiogenol C HCl,Cardiogenol C
Target: Wnt/beta-catenin
DMHCA
T40898
Synonym:
Target:
KYGVSVQDI Acetate
TP2502
Synonym:
Target: Others
OVA G4 peptide acetate(148274-82-2 free base)
TP1591L
Synonym: SIIGFEKL acetate
Target: Others
p2Ca acetate(142606-55-1 free base)
TP1777L
Synonym:
Target: Others
OVA Peptide 257-264 2TFA (138831-86-4 free base)
TP1327L
Synonym: OVA Peptide 257-264 2TFA 1262751-08-5(TFA-2TFA)
Target: Others
FGF22-IN-1
T73133
Synonym:
Target: Others
G280-9 acetate(156761-76-1 free base)
TP1543L
Synonym:
Target: Others
Relatlimab
T9901A-001
Synonym: BMS-986016
Target: Others
ML604440
T12079
Synonym:
Target: Proteasome
glatiramer Acetate
TP2315
Synonym:
Target: Others
A2-Binding peptide
TP2360
Synonym:
Target:
OVA Peptide(257-264)
T7619
Synonym: OVA Peptide 257-264,OVA Peptide 257-264 (2TFA)
Target: Others
Bactobolamine
T83861
Synonym:
Target:
Ieramilimab
T78247
Synonym: IMP701,LAG525
Target:
OVA (55-62)
T39005
Synonym:
Target:
OVA peptide
T81590
Synonym:
Target:
EGFRvIII peptide (PEPvIII)
TP1589
Synonym: EGFRvIII peptide PEPvIII
Target:
OVA Peptide(257-264) TFA
TP1327
Synonym: OVA Peptide (257-264) TFA
Target:
TYVPANASL
T80907
Synonym:
Target:
HBV Seq2 aa:28-39
T76529
Synonym:
Target:
Concanamycin B
T36116
Synonym:
Target:
InsB 9-23
TP1126
Synonym: Insulin B chain (9-23)
Target:
TYVPANASL TFA
T80906
Synonym:
Target:
LLO (91-99) acetate
T38794L
Synonym: LLO (91-99) acetate(137856-41-8 free base)
Target: Others
p2Ca
TP1777
Synonym:
Target:
Miptenalimab
T81790
Synonym: BI-754111
Target:
OVA G4 peptide TFA (148274-82-2 free base)
TP1652
Synonym: OVA G4 peptide TFA
Target:
CFP10 (71–85)
T82743
Synonym:
Target:
VLHDDLLEA
T80857
Synonym:
Target:
LLO (91-99)
T38794
Synonym: LLO (91-99),Listeriolysin O (91-99)
Target:
LCMV gp33-41 TFA
T75982
Synonym:
Target:
Eftilagimod alfa
T78332
Synonym: IMP321,LAG-3Ig
Target:
Encelimab
T82471
Synonym:
Target:
OVA G4 peptide
TP1591
Synonym:
Target:
NY-ESO-1 (87-111)
T40590
Synonym:
Target:
MAGE-A3 (195-203)
TP1502
Synonym: MAGE-A3 195-203
Target:
LCMV gp33-41 (TFA) (151705-84-9 free base)
TP1629
Synonym: LCMV gp33-41 (TFA)
Target:
GAD65 (206-220)
T40115
Synonym: GAD65 (206-220)
Target:
Favezelimab
T82414
Synonym: MK-4280
Target:
LCMV gp33-41
TP1758
Synonym:
Target:
Tyrosinase-related Protein 2 (TRP-2) (181-188)
T39311
Synonym:
Target:
G280-9
TP1543
Synonym:
Target:
Polzastobart
T81423
Synonym: JTX 8064
Target:
Tebotelimab
T76985
Synonym:
Target:
Moth Cytochrome C (MCC) (88-103)
TP1855
Synonym: Moth Cytochrome C (MCC) 88-103
Target:
EGFRvIII Peptide TFA
T83852
Synonym: PEGFRvIII (9-mer),Epidermal Growth Factor Receptor Variant III Peptide
Target:
Cyclic di-IMP (sodium salt)
T36984
Synonym:
Target:
1 2
Cat No. Product Name Synonyms Targets
T0948L Corticosterone 17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,Corticosterone (From plants) Glucocorticoid Receptor , Endogenous Metabolite
Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active. Corticosterone is involved in the regulation of energy, immune responses, and stres...
T5771 Hypocrellin A Antibacterial , PKC , Parasite
Hypocrellin A is PKC inhibitor, has light-induced antitumor,antifungal and antiviral activities, it also exerts immunomodulatory effects on MHC-restricted presentation of antigen.
TN6925 Pristane 2,6,10,14-tetramethylpentadecane Others
Pristane (2,6,10,14-tetramethylpentadecane) is a natural product from shark liver oil and a non-antigenic adjuvant.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01066 MICB Protein, Human, Recombinant (His) Human HEK293
MHC class I polypeptide-related sequence B, also known as MICB, is a heavily glycosylated protein serving as a ligand for the type II receptor NKG2D. MICB shares 85% amino acid identity with MICA, a closely related prote...
TMPY-05476 MICA Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
MHC class I chain-related molecules A (MICA) is one of the genes in the HLA class I region, which belongs to the MHC class I family. It is the member of the non-classical class I family that displays the greatest degree ...
TMPY-02053 MICA Protein, Human, Recombinant (His), MICA*018 Human HEK293
MHC class I chain-related molecules A (MICA) is one of the genes in the HLA class I region, which belongs to the MHC class I family. It is the member of the non-classical class I family that displays the greatest degree ...
TMPK-00836 HLA-G Free Heavy Chain Protein, Human, Recombinant (His & Avi) Human E. coli
HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding const...
TMPY-00885 MICB Protein, Human, Recombinant (His & hFc) Human HEK293
MHC class I polypeptide-related sequence B, also known as MICB, is a heavily glycosylated protein serving as a ligand for the type II receptor NKG2D. MICB shares 85% amino acid identity with MICA, a closely related prote...
TMPJ-00429 CRTAM Protein, Cynomolgus, Recombinant (hFc) Cynomolgus Human Cells
Cytotoxic and Regulatory T-Cell Molecule (CRTAM) is a member of Nectin family under the immunoglobulin superfamily that is expressed by activated CD8+ and NK T cells. CRTAM is found in spleen, thymus, small intestine, pe...
TMPJ-01422 CRTAM Protein, Cynomolgus, Recombinant (His) Cynomolgus Human Cells
Cytotoxic and Regulatory T-Cell Molecule (CRTAM) is a member of Nectin family under the immunoglobulin superfamily that is expressed by activated CD8+ and NK T cells. CRTAM is found in spleen, thymus, small intestine, pe...
TMPK-01418 Peptide Ready HLA-G&B2M Monomer Protein, Human, MHC (His & Avi) Human HEK293
Peptide Ready HLA-G&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-G. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can b...
TMPK-01414 Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein, Mouse, MHC (His & Avi) Mouse HEK293
Qa-1b binds a peptide (AMAPRTLLL), referred to as Qdm (for Qa-1 determinant modifier), derived from the signal sequence of murine class Ia molecules. This peptide binds with high affinity and accounts for almost all of t...
TMPY-05830 MICA Protein, Human, Recombinant (hFc), MICA*018 Human HEK293
MHC class I chain-related molecules A (MICA) is one of the genes in the HLA class I region, which belongs to the MHC class I family. It is the member of the non-classical class I family that displays the greatest degree ...
TMPY-05469 MICA Protein, Human, Recombinant (His), MICA*00801 Human HEK293
MHC class I chain-related molecules A (MICA) is one of the genes in the HLA class I region, which belongs to the MHC class I family. It is the member of the non-classical class I family that displays the greatest degree ...
TMPK-01426 Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi) Human HEK293
Peptide Ready HLA-A*11:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*11:01. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01551 HLA-A*02:01&B2M&GP100 (YLEPGPVTA) Monomer Protein, Human, MHC (His & Avi) Human HEK293
Glycoprotein 100, gp100 or Melanocyte protein PMEL is 661 amino acids long and is a type I transmembrane glycoprotein enriched in melanosomes, which are the melanin-producing organelles in melanocytes. This protein is in...
TMPK-01540 HLA-A*02:01&B2M&GP100 (YLEPGPVTA) Tetramer Protein, Human, MHC (His & Avi) Human HEK293
Glycoprotein 100, gp100 or Melanocyte protein PMEL is 661 amino acids long and is a type I transmembrane glycoprotein enriched in melanosomes, which are the melanin-producing organelles in melanocytes. This protein is in...
TMPK-01542 HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human, MHC (His & Avi) Human HEK293
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-01503 HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein, Human, MHC (His & Avi) Human HEK293
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-01514 HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi) Human HEK293
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPK-01484 HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi) Human HEK293
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01521 HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi) Human HEK293
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01516 HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer Protein, Human, MHC (His & Avi) Human HEK293
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upreg...
TMPK-01520 HLA-A*02:01&B2M&AFP (PLFQVPEPV) Tetramer Protein, Human, MHC (His & Avi) Human HEK293
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01494 HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Tetramer Protein, Human, MHC (His & Avi) Human HEK293
Cancer/testis antigens 83 (CT83), also called KK-LC-1 or CXorf61, recognized by cytotoxic T lymphocytes (CTL), has become a promising target for immunotherapy.
TMPK-01441 HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Monomer Protein, Human, MHC (His & Avi) Human HEK293
PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01409 Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293
Peptide Ready HLA-G&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-G. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can b...
TMPK-01419 Peptide Ready HLA-A*03:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293
Peptide Ready HLA-A*03:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*03:01. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01423 Peptide Ready HLA-E*01:03&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293
HLA-E*01:03&B2M&Peptide ready Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-E*01:03. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01425 Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293
Peptide Ready HLA-A*11:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*11:01. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01502 HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-01545 HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPK-01446 HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, Human, MHC (His & Avi) Human HEK293
MAGE-A1 belongs to the chromosome X-clustered genes of cancer-testis antigen family and is normally expressed in the human germ line but is also overexpressed in various tumors.
TMPK-01465 HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Monomer Protein, Human, MHC (His & Avi) Human HEK293
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01487 HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Monomer Protein, Human, MHC (His & Avi) Human HEK293
Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others.survivin-2B promoted autophagy and further regulated cell de...
TMPK-01463 HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer Protein, Human, MHC (His & Avi) Human HEK293
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01488 HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi) Human HEK293
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01528 HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi) Human HEK293
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01472 HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer Protein, Human, MHC (His & Avi) Human HEK293
Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine im...
TMPK-01458 HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Monomer Protein, Human, MHC (His & Avi) Human HEK293
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01434 HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Tetramer Protein, Human, MHC (His & Avi) Human HEK293
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01512 HLA-A*03:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi) Human HEK293
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01489 HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Tetramer Protein, Human, MHC (His & Avi) Human HEK293
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01411 Peptide Ready HLA-G&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293
Peptide Ready HLA-G&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-G. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can b...
TMPK-01413 H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi) Mouse HEK293
Ovalbumin (OVA) has been historically a popular source of such antigens, since OVA can induce both humoral and cellular immune responses based on well-characterised peptide epitopes. The OVA257-264 octapeptide was one of...
TMPK-01424 Peptide Ready HLA-E*01:03&B2M Monomer Protein, Human, MHC (His & Avi) Human HEK293
HLA-E*01:03&B2M&Peptide ready Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-E*01:03. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01422 Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi) Human HEK293
Peptide Ready HLA-A*02:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*02:01. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01498 HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Tetramer Protein, Human, MHC (His & Avi) Human HEK293
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-01544 HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi) Human HEK293
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPK-01482 HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi) Human HEK293
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01515 HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi) Human HEK293
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01519 HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi) Human HEK293
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01454 HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein, Human, MHC (His & Avi) Human HEK293
PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
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MICB Protein, Human, Recombinant (His)
TMPY-01066
Species: Human
Expression System: HEK293
MICA Protein, Cynomolgus, Recombinant (His)
TMPY-05476
Species: Cynomolgus
Expression System: HEK293
MICA Protein, Human, Recombinant (His), MICA*018
TMPY-02053
Species: Human
Expression System: HEK293
HLA-G Free Heavy Chain Protein, Human, Recombinant (His & Avi)
TMPK-00836
Species: Human
Expression System: E. coli
MICB Protein, Human, Recombinant (His & hFc)
TMPY-00885
Species: Human
Expression System: HEK293
CRTAM Protein, Cynomolgus, Recombinant (hFc)
TMPJ-00429
Species: Cynomolgus
Expression System: Human Cells
CRTAM Protein, Cynomolgus, Recombinant (His)
TMPJ-01422
Species: Cynomolgus
Expression System: Human Cells
Peptide Ready HLA-G&B2M Monomer Protein, Human, MHC (His & Avi)
TMPK-01418
Species: Human
Expression System: HEK293
Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein, Mouse, MHC (His & Avi)
TMPK-01414
Species: Mouse
Expression System: HEK293
MICA Protein, Human, Recombinant (hFc), MICA*018
TMPY-05830
Species: Human
Expression System: HEK293
MICA Protein, Human, Recombinant (His), MICA*00801
TMPY-05469
Species: Human
Expression System: HEK293
Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi)
TMPK-01426
Species: Human
Expression System: HEK293
HLA-A*02:01&B2M&GP100 (YLEPGPVTA) Monomer Protein, Human, MHC (His & Avi)
TMPK-01551
Species: Human
Expression System: HEK293
HLA-A*02:01&B2M&GP100 (YLEPGPVTA) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01540
Species: Human
Expression System: HEK293
HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01542
Species: Human
Expression System: HEK293
HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein, Human, MHC (His & Avi)
TMPK-01503
Species: Human
Expression System: HEK293
HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi)
TMPK-01514
Species: Human
Expression System: HEK293
HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)
TMPK-01484
Species: Human
Expression System: HEK293
HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi)
TMPK-01521
Species: Human
Expression System: HEK293
HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01516
Species: Human
Expression System: HEK293
HLA-A*02:01&B2M&AFP (PLFQVPEPV) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01520
Species: Human
Expression System: HEK293
HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01494
Species: Human
Expression System: HEK293
HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Monomer Protein, Human, MHC (His & Avi)
TMPK-01441
Species: Human
Expression System: HEK293
Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01409
Species: Human
Expression System: HEK293
Peptide Ready HLA-A*03:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01419
Species: Human
Expression System: HEK293
Peptide Ready HLA-E*01:03&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01423
Species: Human
Expression System: HEK293
Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01425
Species: Human
Expression System: HEK293
HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01502
Species: Human
Expression System: HEK293
HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01545
Species: Human
Expression System: HEK293
HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, Human, MHC (His & Avi)
TMPK-01446
Species: Human
Expression System: HEK293
HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Monomer Protein, Human, MHC (His & Avi)
TMPK-01465
Species: Human
Expression System: HEK293
HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Monomer Protein, Human, MHC (His & Avi)
TMPK-01487
Species: Human
Expression System: HEK293
HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer Protein, Human, MHC (His & Avi)
TMPK-01463
Species: Human
Expression System: HEK293
HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi)
TMPK-01488
Species: Human
Expression System: HEK293
HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi)
TMPK-01528
Species: Human
Expression System: HEK293
HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01472
Species: Human
Expression System: HEK293
HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Monomer Protein, Human, MHC (His & Avi)
TMPK-01458
Species: Human
Expression System: HEK293
HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01434
Species: Human
Expression System: HEK293
HLA-A*03:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi)
TMPK-01512
Species: Human
Expression System: HEK293
HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01489
Species: Human
Expression System: HEK293
Peptide Ready HLA-G&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01411
Species: Human
Expression System: HEK293
H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi)
TMPK-01413
Species: Mouse
Expression System: HEK293
Peptide Ready HLA-E*01:03&B2M Monomer Protein, Human, MHC (His & Avi)
TMPK-01424
Species: Human
Expression System: HEK293
Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi)
TMPK-01422
Species: Human
Expression System: HEK293
HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01498
Species: Human
Expression System: HEK293
HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01544
Species: Human
Expression System: HEK293
HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01482
Species: Human
Expression System: HEK293
HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)
TMPK-01515
Species: Human
Expression System: HEK293
HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01519
Species: Human
Expression System: HEK293
HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01454
Species: Human
Expression System: HEK293
TargetMol