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Anti-MICB Antibody (3I896)
😃Good
Catalog No. TMAY-01131
Alias PERB11.2, MHC class I polypeptide-related sequence B
Anti-MICB Antibody (3I896) is a Mouse antibody targeting MICB. Anti-MICB Antibody (3I896) can be used in ELISA,FCM.
Anti-MICB Antibody (3I896)
Anti-MICB Antibody (3I896)
😃Good
Catalog No. TMAY-01131Alias PERB11.2, MHC class I polypeptide-related sequence B
Anti-MICB Antibody (3I896) is a Mouse antibody targeting MICB. Anti-MICB Antibody (3I896) can be used in ELISA,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 20 μL | $70 | 7-10 days | 7-10 days | |
| 100 μL | $198 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-MICB Antibody (3I896) is a Mouse antibody targeting MICB. Anti-MICB Antibody (3I896) can be used in ELISA,FCM. |
| Synonyms | PERB11.2, MHC class I polypeptide-related sequence B |
| Ig Type | Mouse IgG1 |
| Clone | 3I896 |
| Reactivity | Human |
| Specificity | Human MICB |
| Verified Activity | Flow cytometric analysis of anti-MICB on MCF-7 cells. MCF-7 cells were detached using 1X trypsin, washed, then stained with purified mouse anti-MICB. Second step staining with rabbit anti-mouse IgG FC polyclonal antibody. |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000; FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MICB (rh MICB; TMPY-01066; NP_005922.2; Met 1-Gly 298). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | MHC class I polypeptide-related sequence B, also known as MICB, is a heavily glycosylated protein serving as a ligand for the type II receptor NKG2D. MICB shares 85% amino acid identity with MICA, a closely related protein, both of which contain three extracellular immunoglobulin-like domains, but without the capacity to bind peptide or interact with beta-2-microglobulin. acting as a stress-induced self-antigen, binding of MICB to the NKG2D receptor activates the cytolytic response of natural killer (NK) cells, CD8+αβ T cells, and γδ T cells on which the receptor is expressed. MICA/B is minimally expressed on normal cells, but are frequently expressed on epithelial tumors and can be induced by bacterial and viral infections. MICA/B recognition thus is involved in tumor surveillance, viral infections, and autoimmune diseases. |
| Conjucates | Unconjugated |
| Others Formats | APC/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Protein: Human MICB protein (TMPY-01066) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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