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Anti-MICB Antibody-FITC (3I896)
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Catalog No. TMAY-01131F
Alias PERB11.2, MHC class I polypeptide-related sequence B
Anti-MICB Antibody-FITC (3I896) is a FITC-conjugated Mouse antibody targeting MICB. Anti-MICB Antibody-FITC (3I896) can be used in FCM.
Anti-MICB Antibody-FITC (3I896)
Anti-MICB Antibody-FITC (3I896)
😃Good
Catalog No. TMAY-01131FAlias PERB11.2, MHC class I polypeptide-related sequence B
Anti-MICB Antibody-FITC (3I896) is a FITC-conjugated Mouse antibody targeting MICB. Anti-MICB Antibody-FITC (3I896) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 T | 76 € | 7-10 days | |
| 100 T | 243 € | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-MICB Antibody-FITC (3I896) is a FITC-conjugated Mouse antibody targeting MICB. Anti-MICB Antibody-FITC (3I896) can be used in FCM. |
| Alias | PERB11.2, MHC class I polypeptide-related sequence B |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 3I896 |
| Reactivity | Human |
| Verified Activity | Analysis of anti-MICB on HeLa cells. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MICB / MIC-B (rh MICB; TMPY-01066; NP_005922.2; Met 1-Gly 298) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | MHC class I polypeptide-related sequence B, also known as MICB, is a heavily glycosylated protein serving as a ligand for the type II receptor NKG2D. MICB shares 85% amino acid identity with MICA, a closely related protein, both of which contain three extracellular immunoglobulin-like domains, but without the capacity to bind peptide or interact with beta-2-microglobulin. acting as a stress-induced self-antigen, binding of MICB to the NKG2D receptor activates the cytolytic response of natural killer (NK) cells, CD8+αβ T cells, and γδ T cells on which the receptor is expressed. MICA/B is minimally expressed on normal cells, but are frequently expressed on epithelial tumors and can be induced by bacterial and viral infections. MICA/B recognition thus is involved in tumor surveillance, viral infections, and autoimmune diseases. |
| Conjucates | FITC |
| Others Formats | Unconjugated/APC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human MICB protein (TMPY-01066) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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