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Anti-MICB Antibody (6I83) (Synonyms: PERB11.2, MHC class I polypeptide-related sequence B)

Catalog No. TMAY-01130 Copy Product Info
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Anti-MICB Antibody (6I83) is a Mouse antibody targeting MICB. Anti-MICB Antibody (6I83) can be used in ELISA(Cap).

Anti-MICB Antibody (6I83)

Copy Product Info
🥰Excellent
Catalog No. TMAY-01130
Synonyms PERB11.2, MHC class I polypeptide-related sequence B

Anti-MICB Antibody (6I83) is a Mouse antibody targeting MICB. Anti-MICB Antibody (6I83) can be used in ELISA(Cap).

Anti-MICB Antibody
(6I83)
Pack SizePriceUSA StockGlobal StockQuantity
20 μL$687-10 days7-10 days
100 μL$1997-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-MICB Antibody (6I83) is a Mouse antibody targeting MICB. Anti-MICB Antibody (6I83) can be used in ELISA(Cap).
SynonymsPERB11.2, MHC class I polypeptide-related sequence B
Ig Type
Mouse IgG1
Clone
6I83
Reactivity
Human
Specificity
Human MICB
Application
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MICB (rh MICB ; TMPY-01066; NP_005922.2; Met1-Gly298). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundMHC class I polypeptide-related sequence B, also known as MICB, is a heavily glycosylated protein serving as a ligand for the type II receptor NKG2D. MICB shares 85% amino acid identity with MICA, a closely related protein, both of which contain three extracellular immunoglobulin-like domains, but without the capacity to bind peptide or interact with beta-2-microglobulin. acting as a stress-induced self-antigen, binding of MICB to the NKG2D receptor activates the cytolytic response of natural killer (NK) cells, CD8+αβ T cells, and γδ T cells on which the receptor is expressed. MICA/B is minimally expressed on normal cells, but are frequently expressed on epithelial tumors and can be induced by bacterial and viral infections. MICA/B recognition thus is involved in tumor surveillance, viral infections, and autoimmune diseases.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human MICB Protein (TMPY-01066)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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