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Anti-MICB Antibody (2D186)
😃Good
Catalog No. TMAY-01132
Alias PERB11.2, MHC class I polypeptide-related sequence B
Anti-MICB Antibody (2D186) is a Rabbit antibody targeting MICB. Anti-MICB Antibody (2D186) can be used in WB.
Anti-MICB Antibody (2D186)
Anti-MICB Antibody (2D186)
😃Good
Catalog No. TMAY-01132Alias PERB11.2, MHC class I polypeptide-related sequence B
Anti-MICB Antibody (2D186) is a Rabbit antibody targeting MICB. Anti-MICB Antibody (2D186) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-MICB Antibody (2D186) is a Rabbit antibody targeting MICB. Anti-MICB Antibody (2D186) can be used in WB. |
| Alias | PERB11.2, MHC class I polypeptide-related sequence B |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 2D186 |
| Reactivity | Human |
| Verified Activity | Anti-MICB rabbit monoclonal antibody at 1:500 dilution. -Lane A: U87MG Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:40 kDa. -Observed band size:67 kDa |
| Application | WB |
| Recommended Dose | WB: 1:500-1:1000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human MICB (rh MICB ; TMPY-01066; NP_005922.2; Met1-Gly298). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | MHC class I polypeptide-related sequence B, also known as MICB, is a heavily glycosylated protein serving as a ligand for the type II receptor NKG2D. MICB shares 85% amino acid identity with MICA, a closely related protein, both of which contain three extracellular immunoglobulin-like domains, but without the capacity to bind peptide or interact with beta-2-microglobulin. acting as a stress-induced self-antigen, binding of MICB to the NKG2D receptor activates the cytolytic response of natural killer (NK) cells, CD8+αβ T cells, and γδ T cells on which the receptor is expressed. MICA/B is minimally expressed on normal cells, but are frequently expressed on epithelial tumors and can be induced by bacterial and viral infections. MICA/B recognition thus is involved in tumor surveillance, viral infections, and autoimmune diseases. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human MICB protein (TMPY-01066) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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