trkb

TrkB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P15209-2.

Expression system: HEK293 Cells
Length: 1-430, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 1-430, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-430, Partial
Activity: Not Tested

TrkB Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.7 kDa and the accession number is XP_541264.2.

Expression system: HEK293 Cells
Length: 1-429, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 1-429, Partial
Activity: Not Tested

TrkB Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.2 kDa and the accession number is XP_541264.2.

Expression system: E. coli
Length: 129-247, Full Length of Mature Protein
Activity: ELISA

The precursor form of Brain-Derived Neurotrophic Factor (pro-BDNF) interacts preferentially with the pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin and induces neuronal apoptosis, whereas mature BDNF selectively binds with high affinity to the TrkB kinase receptor and promotes the survival, growth and differentiation of neurons. As proneurotrophins and mature neurotrophins elicit opposite biological effects, Pro-BDNF cleavage in the neuronal system is regulated in a specific and cell-context dependent manner. Pro-BDNF plays important role in negative regulation of neurotrophic actions in the brain.

Expression system: E. coli
Length: 139-257, Full Length of Mature Protein
Activity: ELISA