nbd

NBD-Cl (NBD chloride) is a nonfluorescent compound that becomes highly fluorescent after reaction with amino or thiol groups.

NBD-PE is a lipid dye used primarily as a probe to study lipid organisation and dynamics within cell membranes and also to study membrane fusion by fluorescence resonance energy transfer (FRET), Ex=463 nm, Em=536 nm.

NBD-F (4-Fluoro-7-nitrobenzofurazan) is a fluorescent derivatization agent used for amino acid analysis.

NBD-Fructose is a fluorescent derivative of fructose, formed by coupling NBD chloride with the amino group of aminofructose (EX/Em=472/538 nm).

NBD-hydrazine serves as a fluorescent probe that reacts with aldehydes and ketones, exhibiting excitation and emission maxima at 468 and 535 nm, respectively. Additionally, it is utilized as a precursor in creating malondialdehyde-reactive fluorescent probes and as a synthetic intermediate for developing cupric and chromic ion colorimetric sensors.

C12-NBD Sphinganine is a fluorescent substrate for ceramidase, utilized to assess the activity of alkaline and neutral ceramidases from various sources.

C6 NBD L-threo-dihydroceramide is an isomer of dihydroceramide tagged with the fluorescent group C6 NBD, which can be utilized for the detection of ceramide.

C12 NBD Phytoceramide is a ceramide analogue and a fluorescent substrate used to detect ceramidase activity.

TZ-NBD is a dual-channel fluorescence probe characterized by its rapid response and high selectivity, designed for the detection of biothiols both in vitro and in vivo.

8-NBD-cAMP sodium is a fluorescently labeled analog of cyclic adenosine monophosphate (cAMP). It maintains biological activity similar to cAMP by modulating the activity of specific proteins such as EPACs or PKA through binding. 8-NBD-cAMP sodium is utilized in fluorescence competition binding assays to assess the binding affinity of newly synthesized EPAC1 agonists with EPAC1 proteins.

NBD-Stearic acid is stearic acid labeled with a nitrobenzoxadiazole (NBD) fluorophore. It serves as a probe for studying fatty acid uptake or for investigating the ligand binding sites of fatty acid-binding proteins (FABP).

C6 NBD Sphingomyelin (d18:1/6:0) (NBD SM(d18:1/6:0)) is a fluorescent short-chain analog of Sphingomyelin. It exhibits activity of neutral sphingomyelinase (N-SMase).

12-NBD Stearate is a fluorescent fatty acid analog. It can bind to fatty acid binding proteins (FABP) and sterol carrier protein 2 (SCP-2). The overexpression of the 15 kDa isoform of SCP-2 enhances the transport of 12-NBD Stearate. This compound serves as a tool for studying the uptake and internalization of long-chain fatty acids (LCFA) at a microscopic level.

14:0-6:0(C2 NBD) PI(4,5)P2 TEA is a fluorescent lipid labeled with nitrobenzoxadiazole (NBD), exhibiting excitation/emission wavelengths of 460/540 nm.

NBD Palmitic Acid is a fluorescent lipid that contains palmitic acid.

NBD-Pen is a fluorescent probe that detects lipid free radicals in living cells.

C12 NBD sphingomyelin, a fluorescently tagged derivative of sphingomyelin with C12 nitrobenzoxadiazole (C12 NBD), serves as a substrate for sphingomyelinase, facilitating the study of sphingomyelin metabolism and transport (Ex=470 nm, Em=525 nm) [1].

NBD-X, SE, serving as an acceptor fluorophore, facilitates the generation of environment-sensitive bioconjugates [1].

C6 NBD Ceramide is a cell-permeable Golgi fluorescent probe (Ex=466 nm, Em=536 nm), a neuraminidic acid with a green fluorescent tag that can recognize Golgi apparatus in live and fixed cells, observing morphological changes of the Golgi apparatus in live cells. C6 NBD Ceramide can be metabolized intracellularly to generate fluorescent sphingomyelin and glucosylceramide, thus applied in studies of sphingolipid transport and metabolism mechanisms.

C6 NBD Glucosylceramide, a fluorescent derivative of glucosylceramide (Ex=466 nm, Em=535 nm), is utilized to investigate glucosylceramide metabolism and internalization, as well as to assess glucosylceramide synthase activity [1] [2] [3].

SQM-NBD is a potent, selective AIE fluorescent probe with exceptional sensitivity to Cys and Hcy, exhibiting limits of detection (LOD) at 54 nM and 72 nM respectively. It demonstrates good cell permeability and low cytotoxicity, showing promise for Cys/Hcy identification in both physiological and pathological conditions [1].

NBD-amine, a fluorogenic compound, exhibits weak fluorescence in aqueous solutions and pronounced fluorescence within organic solvents, membranes, or hydrophobic environments [1].

NBD Sphingosine (NBD-Sph), a fluorochrome-tagged sphingosine, is used in fluorescence assays for sphingosine kinases [1] [2].

C6-NBD Sphinganine, a fluorescent sphinganine analog, serves as a dye for labeling fatty acids [1].