l-tryptophan

L-Tryptophan (Tryptophane), an essential amino acid, is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid) and of INDOLE ALKALOIDS in plants. It can be a precursor to NIACIN, although inefficiently in mammals.

JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM.

2-Hydroxy L-tryptophan hydrochloride is a naturally occurring amino acid and a precursor to 5-hydroxytryptamine (serotonin). It can increase serotonin production in the brain.

N-Acetyl-L-tryptophan (N-acetyltryptophan) is an inhibitor of neurokinin 1 receptor (NK1-receptor, NK1R).

N-Cbz-DL-tryptophan is a cholecystokinin receptor antagonist, abolished the response of the isolated heart to CCK-8.

Caffeine N-Acetyl-L-Tryptophan is a caffeine salt that stimulates the nervous system and causes vasodilation.

5-Fluoro-L-tryptophan is a competitive inhibitor of the vesicular glutamate transporter (VGLUT). It holds potential for research related to disorders involving neurotransmitter systems.

1,1'-Ethylidene-bis-(L-tryptophan) is a potential impurity in L-tryptophan commercial products, promoting EoL-3 eosinophilic leukemia cell proliferation, enhancing eosinophil cationic protein release from human peripheral blood eosinophils, and boosting IL-5 production in human T cells. At 40 µg/kg, it triggers fascia thickening, mast cell infiltration, inflammation, and fibrosis in mouse superficial adipose and panniculus carnosus tissues, serving as an eosinophilia-myalgia syndrome research model. 1,1'-Ethylidene-bis-(L-tryptophan) is therefore used in immunotoxicology and eosinophil biology research systems to investigate cytokine-driven eosinophilic activation, mast cell infiltration pathways, and fibrosis-associated inflammatory remodeling in in vivo disease modeling contexts.

5-Hydroxy-L-tryptophan-4,6,7-D3 is L-5-Hydroxytryptophan labeled with 2H. L-5-Hydroxytryptophan (L-5-HTP) is a dietary supplement and a precursor to serotonin, which inhibits the IFN-γ induced PD-L1 expression. It promotes anti-tumor immunity and is used in research on migraine and depression.

L-Tryptophan-1-13C is L-Tryptophan (T0439) labeled with carbon-13. L-Tryptophan (T0439) (Tryptophan) is an essential amino acid that serves as a precursor for serotonin, melatonin, and vitamin B3.

L-Tryptophan-D8 is the deuterated form of L-Tryptophan. L-Tryptophan (T0439) (Tryptophan) is an essential amino acid, serving as a precursor for serotonin, melatonin, and vitamin B3.

L-Tryptophan-15N2 is an isotopically labeled form of L-Tryptophan, incorporating 15N. L-Tryptophan (T0439) (Tryptophan) is an essential amino acid that serves as a precursor to serotonin, melatonin, and vitamin B3.

L-Tryptophan-13C11,15N2 is an isotopically labeled version of L-Tryptophan, featuring both 13C and 15N markers. L-Tryptophan (T0439) (Tryptophan) is an essential amino acid that serves as a precursor for serotonin, melatonin, and vitamin B3.

L-Tryptophan-D5 is the deuterated form of L-Tryptophan. L-Tryptophan (T0439) (Tryptophan) is an essential amino acid and serves as a precursor to serotonin, melatonin, and vitamin B3.

L-Tryptophan-13C11 is L-Tryptophan (T0439) labeled with 13C. L-Tryptophan (Tryptophan) is an essential amino acid that serves as a precursor for serotonin, melatonin, and vitamin B3.

L-Tryptophan-13C is a form of L-Tryptophan (T0439) that is labeled with 13C. L-Tryptophan (T0439) (Tryptophan) is an essential amino acid and serves as a precursor to serotonin, melatonin, and vitamin B3.

L-Tryptophan-15N is L-Tryptophan (T0439) labeled with 15N. L-Tryptophan (T0439) (Tryptophan) is an essential amino acid that serves as a precursor to serotonin, melatonin, and vitamin B3.

L-Tryptophan-2,3,3-D3 (Standard) is a standard material used for research and analysis of L-Tryptophan-2,3,3-D3. L-Tryptophan (T0439) is an essential amino acid and a precursor for serotonin synthesis.

N-Acetyl-L-tryptophan-d3 is the deuterium-labeled analogue of N-Acetyl-L-tryptophan. This compound functions as an antagonist of the neurokinin receptor (NK-1R), inhibiting the binding of Substance P (SP) to NK-1R and providing neuroprotective effects that improve memory impairment and motor dysfunction. Additionally, N-Acetyl-L-tryptophan acts as an inhibitor of mitochondrial cytochrome c (Cytochrome c), offering antioxidant and anti-inflammatory benefits by reducing IL-1β expression and inhibiting caspase-1 activation. N-Acetyl-L-tryptophan shows potential for research in neurodegenerative and inflammatory disease contexts.

L-Tryptophan (Standard) is a reference standard of L-tryptophan, suitable for quantitative analysis, quality control, and biochemical studies. L-Tryptophan is an essential amino acid that serves as a precursor for the biosynthesis of serotonin, melatonin, and vitamin B3, and plays important roles in neuroregulation and metabolism. In addition, L-tryptophan and its metabolic pathways can regulate the differentiation potential of bone marrow mesenchymal stem cells and may influence cell proliferation under specific conditions.

L-Tryptophan-13C (Standard) is a reference standard of L-Tryptophan-13C intended for quantitative analysis, quality control, and related biochemical research applications. L-Tryptophan-13C is a form of L-Tryptophan that is labeled with 13C. L-Tryptophan (Tryptophan) is an essential amino acid and serves as a precursor to serotonin, melatonin, and vitamin B3.

5-Hydroxy-L-Tryptophan-4,6,7-D3 (Standard) is a reference standard of 5-Hydroxy-L-Tryptophan-4,6,7-D3 intended for quantitative analysis, quality control, and related biochemical research applications. 5-Hydroxy-L-tryptophan-4,6,7-d3 is L-5-Hydroxytryptophan labeled with 2H. L-5-Hydroxytryptophan (L-5-HTP) is a dietary supplement and a precursor to serotonin, which inhibits the IFN-γ induced PD-L1 expression. It promotes anti-tumor immunity and is used in research on migraine and depression.

L-Tryptophan-D5 (Standard) is a reference standard of L-Tryptophan-D5 intended for quantitative analysis, quality control, and related biochemical research applications. L-Tryptophan-d5 is the deuterated form of L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid and serves as a precursor to serotonin, melatonin, and vitamin B3.

2-α-D-Mannopyranosyl-L-tryptophan is a naturally occurring C-glycosyl amino acid and serves as a biomarker of renal function.