l 35

L 35 is kind of a negative effector of hemoglobin.

Poloxamer 105 L35 is a block copolymer of polyethylene oxide and polypropylene oxide, with an average molecular weight of 1900. It forms thermoreversible hydrogels and is utilized as a food additive, as well as a drug delivery vehicle in cosmetics, pharmaceuticals, and tissue engineering.

Poly(D,L-lactide-co-glycolide), 65:35 (PGCL, 65:35), is a copolymer formed by the ring-opening polymerization of lactide and glycolide, and is used for drug delivery.

BI-L 357, a prodrug of BL-L 226, is a selective, orally active inhibitor of 5-lipoxygenase.

1-(2-fluorophenyl)-3-[5-(2-methoxyphenyl)-1,3,4-thiadiazol-2-yl]urea is a chemical compound.

ML353 (VU0478006) is a selective activator of TREK-1 and TREK-2 and a selective ligand (Ki =18.2 nM) for the mGlu5 Silencing Allosteric Modulator (SAM). ML353 has potential as a solution to the intrinsic activity or pharmacological blockade of SAM in vivo.

Cremophor EL is a nonionic surfactant. cremophor EL inhibits cellular metabolism and suppresses UGT1A1-mediated rhodopsin glucuronidation.

N-Chloroacetyl-3,5-bis(trifluoromethyl)aniline (KM1954) is an insecticide, it is most active against 1st stage Ae. aegypti larvae with LC50 values of 125μM.

DDL-357 is a potent enhancer of secretory cluster proteins. It reduces phosphorylated tau protein levels in the brains of 3xTg-AD model mice and improves their memory.

ML352 is a selective and potent inhibitor of the presynaptic choline transporter (CHT), inhibits non-competitive choline uptake.

ML-354 (VU0099704) is a selective and potent PAR4 antagonist for the study of cardiovascular disease.

ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).

ML350 (CYM-50202) is a KOR (IC50: 12.6 nM) antagonist with good and moderate selectivity against the DOR and MOR. CYM-50202 displayed high solubility and excellent CNS penetration. CYM-50202 did not display long-lasting pharmacodynamic effects observed wi

ML358 is a selective SKN-1 pathway inhibitor involved in drug detoxification and resistance in nematodes.

ML359 is a protein disulfide isomerase inhibitor.

(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine (CSTMP) is a stilbene derivative with antioxidant and anticancer activities. It stimulates proliferation of hydrogen peroxide-damaged ECV-304 cells (EC50 = 24.9 nM). CSTMP reduces hydrogen peroxide-induced release of lactate dehydrogenase (LDH) in and increases viability of human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner via inhibition of apoptosis. It reverses hydrogen peroxide-induced release of malondialdehyde (MDA) and decreases in superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities as well as increases constitutive nitric oxide synthase (cNOS) activity and nitric oxide (NO) production in HUVECs. CSTMP also induces cell death of A549 non-small cell lung cancer (NSCLC) cells in an IRE1α-dependent manner through induction of IRE1α-TRAF2-ASK1 complex-mediated endoplasmic reticulum (ER) stress and mitochondrial apoptosis.

ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.

KKL-35 is an inhibitor of trans-translation (IC50: 0.9 µM) with broad-spectrum antibiotic activity.

JNJ-10229570 (UNII-N9IX402L35) is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids.

(2'R,7R,8R,10S,13S,14S)-Methyl 10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,10,12,13,14,15,16-tetradecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T65404 and the CAS number is 95716-70-4.

(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl) methylamino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester is a useful organic compound for research related to life sciences. The catalog number is T65944 and the CAS number is 355806-00-7.

2-(Chloromethyl)-3,5-dimethyl-4-nitropyridine is a useful organic compound for research related to life sciences. The catalog number is T65985 and the CAS number is 153476-68-7.

(3R,5R)-tert-Butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate is a useful organic compound for research related to life sciences. The catalog number is T66068 and the CAS number is 134395-00-9.

t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate is a useful organic compound for research related to life sciences. The catalog number is T66069 and the CAS number is 147489-06-3.