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Results for "

gram-positive bacterial

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    151
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    TargetMol | Inhibitors_Agonists
Glyceryl monocaprate
Monocaprin, DECANOIN, 2,3-Dihydroxypropyl decanoate
T1539426402-22-2
Glyceryl monocaprate (2,3-Dihydroxypropyl decanoate) has inhibitory effect on Herpes Simplex Virus (HSV). It also offers an effective treatment for herpes labialiss. Glyceryl monocaprate is a capric acid against 1-monoglyceride gram-positive bacterial infections.
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Spectinomycin dihydrochloride
Spectinomycin 2HCl, Actinospectacin
T078821736-83-4
Spectinomycin dihydrochloride (Actinospectacin) is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
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Oxytetracycline
Terramycin
T089579-57-2
Oxytetracycline (Terramycin) is a TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions.
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Chlortetracycline hydrochloride
Isphamycin, Chlortetracycline HCl, 7-Chlorotetracycline hydrochloride
T130464-72-2
Chlortetracycline Hydrochloride is a tetracycline with broad-spectrum antibacterial and antiprotozoal activity. Chlortetracycline hydrochloride (Isphamycin) is bacteriostatic and inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the addition of amino acids to the growing peptide chain. This tetracycline is active against a wide range of gram-positive and gram-negative organisms, spirochetes, rickettsial species, certain protozoa and Mycoplasma and Chlamydia organisms.
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Imipenem monohydrate
N-Formimidoyl thienamycin monohydrate
T150574431-23-5
Imipenem monohydrate (Imipenem) is a carbapenem antibiotic isolated from the microorganism Streptomyces cattleya, and is a β lactam antibiotic. Imipenem monohydrate acts on the bacterial cell wall, and is a broadly effective inhibitor of a wide range of Gram-positive and negative bacteria.
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5-Bromo-5-nitro-1,3-dioxane
Bronidox
T1980830007-47-7
5-Bromo-5-nitro-1,3-dioxane (Bronidox) is an antimicrobial compound that inhibits bacterial enzyme activity.
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Cefoxitin
Rephoxitin, Cefoxitinum
T2064335607-66-0
Cefoxitin (Rephoxitin) is a broad-spectrum, orally available second-generation cephalosporins antibiotic. Cefoxitin interferes with the synthesis of bacterial cell walls. Its activity profile includes Gram-negative and Gram-positive bacteria, and is commonly used in abdominal cavity infections, pelvic infections, and certain types of gynecological infections, and is highly effective against anaerobic bacteria.
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7-10 days
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Oxytetracycline Hydrochloride
Biosolvomycin, Oxytetracycline HCl, Oxytetracycline.HCl, Dalimycin, Oxytetracycline, Sodium Salt, Dalinmycin
T214302058-46-0
Oxytetracycline Hydrochloride (Dalimycin) is a tetracycline derivative produced by Streptomyces rimosus with antimicrobial activity. It interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, resulting in preventing peptide elongation and inhibiting protein synthesis.
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Rifamycin sodium
Rifamycin sodium salt
T500314897-39-3
Rifamycin sodium (Rifamycin sodium salt) salt is an antibiotic that inhibits bacterial DNA-dependent RNA polymerase. It is effective against Gram-positive bacteria.
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Midecamycin
Antibiotic SF-837, Turimycin P3, Medecamycin A1, Rubimycin, Platenomycin B1, Espinomycin A
T503735457-80-8
Midecamycin (Medecamycin A1), an acetoxy-substituted macrolide antibiotic, has effective on gram-positive and gram-negative bacteria acts by inhibiting bacterial protein synthesis.
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Oxytetracycline Dihydrate
Terramycin Dihydrate
T66246153-64-6
Oxytetracycline Dihydrate (Terramycin Dihydrate) is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.
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bekanamycin
Kanamycin B
T81184696-76-8
Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic.
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Cefodizime Sodium
T812686329-79-5
Cefodizime Sodium is a third generation cephalosporin antibiotic, has broad-spectrum activity
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Gramicidin
Gramicidinum, Gramicidine, Gramicidina
T11301405-97-6
Gramicidin (Gramicidine) is an antimicrobial peptide. Gramicidin dimers form ion channel-like pores in the cell membranes and organelles of bacterial and animal cells, allowing inorganic monovalent ions, such as potassium and sodium ions, to pass freely through the pores by diffusion, disrupting the important ionic gradient between membranes and thus killing the cells by various actions. Gramicidin is effective against Gram-positive bacteria such as Bacillus subtilis and Staphylococcus aureus, but is not as effective against Gram-negative bacteria such as Escherichia coli.
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Nonacosane
T2P2937630-03-5
Nonacosane is a straight-chain alkane comprising of 29 carbon atoms. It has a role as a plant metabolite and a volatile oil component.
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TargetMol | Inhibitor Sale
Calcimycin
Antibiotic A-23187, A-23187
T10662L52665-69-7
Calcimycin (A-23187) is an ionophorous, polyether carboxylic antibiotic from Streptomyces chartreusensis. It binds and transports calcium and other divalent cations across membranes, uncouples oxidative phosphorylation, and inhibits ATPase of rat liver mitochondria. The substance is primarily used as a biochemical tool to study the role of divalent cations in various biological systems.
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Equisetin
T1121957749-43-6
Equisetin, an N-methylserine-derived acyl tetramic acid isolated from the terrestrial fungus Fusarium equiseti NRRL 5537, functions as a Quorum-sensing inhibitor (QSI) that specifically attenuates QS-regulated virulence phenotypes in P. aeruginosa, presenting a potent lead for treating P. aeruginosa infections without hindering bacterial growth. This tetramate-containing natural product possesses antibiotic and cytotoxic properties, effectively inhibiting the growth of Gram-positive bacteria and HIV-1 integrase activity, yet it does not impact Gram-negative bacteria.
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10-14 weeks
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Pseudouridimycin
PUM
T166731566586-52-4
Pseudouridimycin is a C-nucleoside analogue. Pseudouridimycin is an antibiotic and is a selective bacterial RNA polymerase (RNAP) inhibitor. It is effective against both Gram-negative and Gram-positive bacteria.
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Violacein
T35751548-54-9
Violacein is a bacterial metabolite originally isolated from C. violaceum that has antibacterial and antiprotozoal activities.[1] [2] It is produced by C. violaceum as a purple pigment in response to N-hexanoyl homoserine lactone , a property that has been modified to create a strain of C. violaceum used in detecting quorum-sensing molecules.[3] Violacein is active against Gram-positive bacteria, including B. subtilis and S. aureus (MICs = 0.8 and 1.6 µM, respectively). It is also active against P. falciparum, including chloroquine-susceptible and -resistant strains (IC50s = 0.85 and 0.63 µM, respectively).[2] It reduces parasitemia in a mouse model of nonlethal P. chabaudi chabaudi infection when administered at a dose of 7.5 mg/kg and increases survival in a mouse model of lethal P. chabaudi chabaudi infection. Violacein permeabilizes the cytoplasmic membrane of bacterial cells but does not affect the cell wall.[1]
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Moenomycin Complex
Flavomycin
T3699011015-37-5
Moenomycin complex is a mixture of moenomycins A, A12, C1, C3 and C4, which are antibiotics isolated from several strains of Streptomyces that directly inhibit bacterial peptidoglycan glycosyltransferases. The minimal inhibitory concentration of moenomycin A against various Gram-positive bacteria ranges from 1-100 nM.
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1-Monomyristin
rac-Glycerol 1-myristate, Glyceryl myristate, Monomyristin, 2,3-Dihydroxypropyl tetradecanoate
T4859589-68-4
1-Monomyristin (2,3-Dihydroxypropyl tetradecanoate) , a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterial strains. 1-Myristoyl-rac-glycerol is used in colloidal chemistry as a nonionic surfactant in the development of micelles.
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Pogostone
DHELWANGIN
T4S086723800-56-8
1. Pogostone (DHELWANGIN) possesses potent anti-bacterial and anti-fungal activities, such as gram negative bacteria , gram positive bacteria, Escherichia coli. 2. Pogostone exhibits an immunosuppressive property by directly blocking T cell proliferation as well as altering inflammatory cytokine profile. 3. Pogostone could exert a gastro-protective effect against gastric ulceration, and the underlying mechanism might be associated with the stimulation of PGE2, improvement of antioxidant and anti-inflammatory status, as well as preservation of NP-SH.
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Ribostamycin
T7420725546-65-0
Ribostamycin (Vistamycin), a broad-spectrum aminoglycoside antibiotic, demonstrates efficacy against both Gram-Negative and Gram-Positive bacterial infections. Additionally, it inhibits the chaperone activity of PDI [1] [2].
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EGCG Octaacetate
T8160148707-39-5
EGCG Octaacetate, a prodrug of EGCG, is utilized to enhance the stability and bioavailability of EGCG in vivo. It has high efficacy, bioavailability, anti-oxidation, and anti-angiogenesis capacities.
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