as-19

AS-1940477 hydrobromide is a p38 mitogen-activated protein kinase (MAPK) inhibitor.

AS19 is a potent, selective 5-HT7 receptor agonist (IC50: 0.83 nM; Ki: 0.6 nM) with demonstrated selectivity for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Kis: 89.7 nM, 490 nM, 6.6 nM, and 98.5 nM, respectively).

Tocilizumab (Anti-Human IL6R) is a neutralizing antibody against human interleukin-6 receptor (IL-6R) that blocks the binding of IL-6 to IL-6R, thereby inhibiting both classical and trans signaling. It can be used to study rheumatoid arthritis and has been suggested as a possible drug for the treatment of severe COVID-19.

AZ10606120 dihydrochloride is a selectable, potent, high-affinity receptor antagonist with K D values of 1.4 and 19 nM at human and rat P2X 7 receptors, respectively. AZ10606120 dihydrochloride inhibits tumor growth and has anti-angiogenic activity. AZ 10606120 acts as a negative allosteric modulator when bound to a site coupled to the ATP binding site.

Compound Fr12274, with CAS No. 1078-19-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12274 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr12556, with CAS No. 574-19-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12556 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr13812, with CAS No. 38041-19-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13812 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr13930, with CAS No. 612-19-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13930 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14040, with CAS No. 91-19-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14040 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14095, with CAS No. 35704-19-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14095 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr16603, with CAS No. 65079-19-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr16603 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr16694, with CAS No. 5369-19-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr16694 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr16721, with CAS No. 143659-19-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr16721 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4(1H)-Quinazolinone, 5,6,7,8-tetrahydro- (9CI), with CAS No. 19178-19-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4(1H)-Quinazolinone, 5,6,7,8-tetrahydro- (9CI) provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Imiquimod (R 837) is an immune response modifier and a toll-like receptor 7 (TLR7) agonist with antiviral and antitumor effects. It is used in the study of external genital warts, perianal warts, cancer, and COVID-19, and is commonly employed to induce psoriasis models.

Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs).

Molnupiravir (EIDD-2801) is an isopropyl ester prodrug of the ribonucleoside analog EIDD-1931 with oral bioavailability. Molnupiravir can be used in the study of COVID-19, seasonal and pandemic influenza, and has broad-spectrum antiviral activity against multiple coronaviruses and influenza viruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV.

Hydroxychloroquine (2-[[4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol) (HCQ) is an alkalinizing lysosomatropic drug that acts by inducing apoptosis of renal cancer cells in vitro and inhibiting TLR7/9. It is a medication used to prevent and treat malaria, and it's also being studied as an experimental treatment for COVID-19.

7-Keto DHEA binds to the gamma-aminobutyric acid (GABA) receptor. Studies 7-Keto DHEA reduces ethanol intake in rat models, indicating a modulatory effect on alcohol consumption behavior. 7-Keto DHEA therefore exhibits potential as a investigational compound of alcohol dependence disorders, contributing to the broader field of addiction research.

Compound 79560-19-3, with CAS No. 79560-19-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound 79560-19-3 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

5-chloro-2-Thiopheneacetic acid, with CAS No. 13669-19-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-chloro-2-Thiopheneacetic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

3-Bromo-5H,6H,7H,8H-imidazo[1,2-a]pyrazine, with CAS No. 954239-19-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-Bromo-5H,6H,7H,8H-imidazo[1,2-a]pyrazine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound FL0213, with CAS No. 173340-19-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0213 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr12205, with CAS No. 184098-19-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12205 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.