aroma

(-)-α-Terpineol has antitumour, anti-inflammatory, and antimicrobial activities, it inhibits the growth of tumour cells through a mechanism that involves inhibition of the NF-kappaB pathway

Heneicosane (henicosane) is a pheromone that inhibits the production of aflatoxins. Heneicosane is an aroma component isolated from Streptomyces philanthi RL-1-178 or Serapias cordigera.

1-Nonadecanol is a saturated fatty alcohol. 1-Nonadecanol is one of the compositions of supercritical carbon dioxide (SC-CO2) essential oil of Heracleum thomsonii. 1-Nonadecanol is also an important aroma compound in Neotinea ustulata.

2,5-Dimethyl-3(2H)-furanone (2,5-Dimethyl-2,3-dihydrofuran-3-one) is a non-genotoxic flavoring substance [1].

Rapidase Revelation Aroma (AR2000), derived from Aspergillus niger, is a biocatalyst that serves as a pivotal enzyme in new biocatalyst technologies. Enzyme engineering focuses on enhancing reaction kinetics, substrate selectivity, and activity under extreme conditions, such as low or high pH. Additionally, the introduction of stimuli-responsive modifications allows for dynamic control of enzyme activity.

Aromatase-IN-2 has anti-inflammatory, antitumor and antiasthmatic effects.

Aromadendrin 4'-glucoside is a useful organic compound for research related to life sciences. The catalog number is T124038 and the CAS number is 87314-52-1.

Aromadendrin 6-C-glucoside is a useful organic compound for research related to life sciences and the catalog number is T126381.

Alloaromandendrane-4alpha,10beta-diol is a useful organic compound for research related to life sciences and the catalog number is T131584.

Paromamine is an antibiotic that targets and identifies ribosomal RNA (rRNA) components.

Aromatase-IN-4 (Compound 6a) is an inhibitor of the enzyme aromatase. It displays anticancer properties, with GI50 values for different cell lines as follows: 2.95 μM for MDAMB-231, 3.35 μM for MCF-7, 2.27 μM for A-549, 8.46 nM for NCI-H23, and 1.56 μM for A-498. Aromatase-IN-4 effectively blocks the estrogen production that depends on aromatase.

Aromatase-IN-5 (Compound 10) is a potent inhibitor of aromatase with an IC50 value of 0.06 μM. It effectively blocks estrogen production and inhibits the proliferation of breast cancer cell lines such as MCF-7, arresting the cell cycle in the G1 phase and inducing apoptosis. Aromatase-IN-5 shows promise for breast cancer research.

Aromatase-IN-3 (compound 7d) is an aromatase inhibitor with an IC50 of 54 nM. It effectively suppresses the conversion of androstenedione to estrogen catalyzed by aromatase, demonstrating significant tumor growth inhibition in breast cancer cell lines, suggesting its potential application in ER+ cancer research.

Aromatase-IN-7 (compound 75) is a potent and selective aromatase inhibitor with an IC50 of 5.78 nM, demonstrating efficacy comparable to Letrozole. It exhibits significant aromatase inhibitory activity both in vitro and in vivo. Aromatase-IN-7 is applicable for research in hormone-dependent breast cancer (HDBC).

Aromatase-IN-8 is a selective aromatase inhibitor with an IC50 of 0.05 µM for aromatase activity. It exhibits selective antiproliferative effects on estrogen receptor-positive breast cancer cell lines while being non-toxic to non-tumor cells. Aromatase-IN-8 suppresses estrogen activity, elevates testosterone levels, and downregulates estrogen receptor expression and phosphorylation. It is applicable for research in triple-negative breast cancer.

COX-2/Aromatase-IN-2 is a dual inhibitor of COX-2 and aromatase (aromatase). It effectively suppresses both COX-2 and aromatase, leading to significant inhibition of inflammation (Inflammation) and the proliferation of breast cancer cells. In the MCF-7 breast cancer cell model and rat paw edema inflammation model, COX-2/Aromatase-IN-2 exhibits notable anti-breast cancer and anti-inflammatory effects. This compound is applicable for research related to inflammation and breast cancer.

Aromatase-IN-1 is a competitive inhibitor of aromatase (P450arom) with an IC50 of 40 nM and a Ki of 1.05 nM against human targets. It binds to the heme iron of aromatase via an imidazole nitrogen atom. Aromatase-IN-1 is applicable for studies related to breast cancer.

l-Aromadendrene is a bioactive chemical.

Aromatase inhibitor 23 is an inhibitor that target protein-protein interactions in RAD51 family of recombinases.

Nonsteroidal aromatase inhibitor 1 (Compound 13h) effectively inhibits the enzyme CYP19A1 with an IC50 value of 0.09 nM. This potent inhibitory activity suggests its potential for breast cancer research [1].

Monoamine oxidase/Aromatase-IN-1 (compound 2q) is a potent dual inhibitor of monoamine oxidase (MAO) and aromatase, with IC50 values of 39 nM for MAO-B and 31 nM for aromatase. It holds significant potential for research in neurological disorders and breast cancer [1].

(+)-Aromadendrene is a natural product that has significant antibacterial activity against the Gram-positive and Gram-negative bacteria.

Alloaromadendrene, an antioxidant isolated from the leaves of mixed-type C. osmophloeum, protects C. elegans against oxidative stress induced by walnut quinone and prolongs the life of C. elegans [1].

Aromatherapy Volatile Oil (Standard) is a reference standard of Aromatherapy Volatile Oil intended for quantitative analysis, quality control, and related biochemical research applications.