Reductase

Reductase is an enzyme that catalyzes a reduction reaction.

Cat No.	product name
TN3760	Danshenol A	Danshenol A has strong aldose reductase (AR) inhibitory activity, has IC50 of 0.10 microM which is comparable to that of epalrestat in clinical use. Danshenol A ...
T5015	Gonadorelin Acetate (33515-09-2 free base)	Gonadorelin Acetate is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.
T3915	Ginsenoside Ro	GinsenosideRo exhibits a Ca2+-antagonistic antiplatelet effect.
T3665	Tectoridin	Tectoridin possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflamm...
T2013	Ponalrestat	Ponalrestat is an aldose reductase inhibitor.
T1458	Epalrestat	Epalrestat, an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy a...
T0725	Isoliquiritigenin	Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, suppresses aldose reductase (IC50=320 nM).
T0488	Finasteride	Finasteride is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.
T5S0543	Isocurcumenol	1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).
T6S0840	Engeletin	1. Engeletin may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engele...
T6102	2'-acetylacteoside	2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-Ac...
T6S2384	Poliumoside	Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exhi...
T5015	Gonadorelin Acetate (33515-09-2 free base)	Gonadorelin Acetate is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.
TN3287	8-Lavandulylkaempferol	8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase and acetylcholinesterase, res...
T5195	Alrestatin	Alrestatin is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.
T4918	DL-Glyceraldehyde	Glyceraldehyde is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When p...
T5813	BYAKANGELICIN	BYAKANGELICIN,a main furanocoumarin constituent isolated and characterized as an aldose reductase inhibitor,and is effective for the treatment of sugar cataracts...
T7478	2-Chloro-1-(4-fluorobenzyl)benzimidazole	2-Chloro-1-(4-fluorobenzyl)benzimidazole is an inhibitor of aldose reductase (ALR2).
TN2295	Vicenin -1	Vicenin-1 possesses potent anti-inflammatory and anti-oxidant activity.
T10393	AT-007	AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and prev...
T15281	Fidarestat	Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10, and V301L AKR1B10, respectively). It has the potent...
T16910	Sorbinil	Sorbinil is an Aldose reductase inhibitor. Sorbinil plays a therapeutic role in treating diabetes and diabetic complications decreases AR activity and inhibit th...
T17114	Tolrestat	Tolrestat is a potent and orally active inhibitor of aldose reductase (IC50: 35 nM).
TN2601	12-O-Methylcarnosic acid	12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibiti...
TN2601	12-O-Methylcarnosic acid	12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibiti...
T1499	Dutasteride	Dutasteride is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperplasia.