Reductase

Reductase is an enzyme that catalyzes a reduction reaction.

Cat No.	product name
T0488	Finasteride	Finasteride is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.
T0725	Isoliquiritigenin	Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, suppresses aldose reductase (IC50=320 nM).
T1458	Epalrestat	Epalrestat, an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy ...
T1499	Dutasteride	Dutasteride is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperplasia.
T2013	Ponalrestat	Ponalrestat is an aldose reductase inhibitor.
T3665	Tectoridin	Tectoridin possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflam...
T3915	Ginsenoside Ro	GinsenosideRo exhibits a Ca2+-antagonistic antiplatelet effect.
T6S0840	Engeletin	1. Engeletin may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engel...
T6102	2'-acetylacteoside	2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-A...
T6S2384	Poliumoside	Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exh...
T5195	Alrestatin	Alrestatin is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.
T4918	DL-Glyceraldehyde	Glyceraldehyde is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When ...
T5813	BYAKANGELICIN	BYAKANGELICIN,a main furanocoumarin constituent isolated and characterized as an aldose reductase inhibitor,and is effective for the treatment of sugar cataract...
TN2295	Vicenin -1	Vicenin-1 possesses potent anti-inflammatory and anti-oxidant activity.
T10393	AT-007	AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and pre...
T15281	Fidarestat	Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10, and V301L AKR1B10, respectively). It has the poten...
T17114	Tolrestat	Tolrestat is a potent and orally active inhibitor of aldose reductase (IC50: 35 nM).
TN3287	8-Lavandulylkaempferol	8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase and acetylcholinesterase, re...
TN3760	Danshenol A	Danshenol A has strong aldose reductase (AR) inhibitory activity, has IC50 of 0.10 microM which is comparable to that of epalrestat in clinical use. Danshenol A...
T5015	Gonadorelin Acetate (33515-09-2 free base)	Gonadorelin Acetate is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.
T5015	Gonadorelin Acetate (33515-09-2 free base)	Gonadorelin Acetate is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.
TN2601	12-O-Methylcarnosic acid	12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibit...
TN2601	12-O-Methylcarnosic acid	12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibit...
T7478	2-Chloro-1-(4-fluorobenzyl)benzimidazole	2-Chloro-1-(4-fluorobenzyl)benzimidazole is an inhibitor of aldose reductase (ALR2).
T5S0543	Isocurcumenol	1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).