TN3760 |
Danshenol A
|
189308-08-5
|
98%
|
|
Danshenol A has strong aldose reductase (AR) inhibitory activity, has IC50 of 0.10 microM which is comparable to that of epalrestat in clinical use. Danshenol A ...
|
TN3287 |
8-Lavandulylkaempferol
|
883859-83-4
|
98%
|
|
8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase and acetylcholinesterase, res...
|
TN5153 |
Torilin
|
13018-10-5
|
98%
|
|
Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) shows a stronger inhibition of 5 alpha-reductase than alpha-linolenic...
|
T15281 |
Fidarestat
|
136087-85-9
|
98%
|
|
Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10, and V301L AKR1B10, respectively). It has the potentia...
|
T6S0840 |
Engeletin
|
572-31-6
|
99.99%
|
|
1. Engeletin (Dihydrokaempferol 3-rhamnoside) may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5...
|
T16910 |
Sorbinil
|
68367-52-2
|
99.89%
|
|
Sorbinil is an Aldose reductase inhibitor. Sorbinil plays a therapeutic role in treating diabetes and diabetic complications decreases AR activity and inhibit th...
|
T5813 |
BYAKANGELICIN
|
482-25-7
|
99.86%
|
|
BYAKANGELICIN,a main furanocoumarin constituent isolated and characterized as an aldose reductase inhibitor,and is effective for the treatment of sugar cataracts...
|
T15756 |
Lidorestat
|
245116-90-9
|
99.84%
|
|
Lidorestat (IDD-676) is an aldose reductase inhibitor (IC50: 5 nM) with effective, selective and oral activity. Lidorestat improves nerve conduction and reduces ...
|
T14175 |
Aldose reductase-IN-1
|
1355612-71-3
|
99.82%
|
|
Aldose reductase-IN-1 (AT-001) is a aldose reductase inhibitor (IC50: 28.9 pM).
|
T5195 |
Alrestatin
|
51411-04-2
|
99.76%
|
|
Alrestatin (AY-22284) is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro...
|
T71703L |
Isomer-Turosteride
|
|
99.72%
|
|
Isomer-Turosteride (Isomer-Turosteride(Isomer-137099-09-3)) is a novel 5 alpha-reductase inhibitor.The antiprostatic effect of Isomer-Turosteride in adult rats i...
|
T1499 |
Dutasteride
|
164656-23-9
|
99.68%
|
|
Dutasteride (GI 198745) is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperpl...
|
T3378 |
Alpha-Estradiol
|
57-91-0
|
99.61%
|
|
Alpha-Estradiol (Epiestradiol) is an estrogen that inhibits 5alpha-reductase and has potential in the study of androgenetic alopecia.
|
T6S2384 |
Poliumoside
|
94079-81-9
|
99.59%
|
|
Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exhib...
|
T27643 |
Izonsteride
|
176975-26-1
|
99.55%
|
|
Izonsteride (LY320236) is a selective and potent 5alpha reductase inhibitor with dual action on the type I and type II isoforms of the enzyme.Izonsteride is used...
|
T19265 |
D-Methionine sulfoxide
|
21056-56-4
|
99.54%
|
|
D-Methionine sulfoxide inhibits peptide methionine sulfoxide reductase and can be used to inhibit ochre mites.D-Methionine sulfoxide can be added to chicken feed...
|
T10393 |
AT-007
|
2170729-29-8
|
99.36%
|
|
AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and prev...
|
TN2122 |
Quercetin 3-gentiobioside
|
7431-83-6
|
99.29%
|
|
Quercetin 3-gentiobioside (Quercetin-3-gentiobioside) is an inhibitor of AR and AGE formation and can be extracted from A. iwayomogi.Quercetin 3-gentiobioside in...
|
TN2601 |
12-O-Methylcarnosic acid
|
62201-71-2
|
99.24%
|
|
12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from Salvia microphylla, is an active constituent of 5α-Reductase inhibition with an IC50 value of...
|
T0725 |
Isoliquiritigenin
|
961-29-5
|
99.21%
|
|
Isoliquiritigenin (ISL), an anti-tumor flavonoid from the root of Glycyrrhiza glabra, suppresses aldose reductase (IC50=320 nM).
|