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Metabolism Reductase

Reductase

Reductase is an enzyme that catalyzes a reduction reaction.
Cat No. product name
TN3760 Danshenol A Danshenol A has strong aldose reductase (AR) inhibitory activity, has IC50 of 0.10 microM which is comparable to that of epalrestat in clinical use. Danshenol A ...
T5015 Gonadorelin Acetate (33515-09-2 free base) Gonadorelin Acetate is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.
T3915 Ginsenoside Ro GinsenosideRo exhibits a Ca2+-antagonistic antiplatelet effect.
T3665 Tectoridin Tectoridin possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflamm...
T2013 Ponalrestat Ponalrestat is an aldose reductase inhibitor.
T1458 Epalrestat Epalrestat, an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy a...
T0725 Isoliquiritigenin Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, suppresses aldose reductase (IC50=320 nM).
T0488 Finasteride Finasteride is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.
T5S0543 Isocurcumenol 1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).
T6S0840 Engeletin 1. Engeletin may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engele...
T6102 2'-acetylacteoside 2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-Ac...
T6S2384 Poliumoside Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exhi...
T5015 Gonadorelin Acetate (33515-09-2 free base) Gonadorelin Acetate is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.
TN3287 8-Lavandulylkaempferol 8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase and acetylcholinesterase, res...
T5195 Alrestatin Alrestatin is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.
T4918 DL-Glyceraldehyde Glyceraldehyde is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When p...
T5813 BYAKANGELICIN BYAKANGELICIN,a main furanocoumarin constituent isolated and characterized as an aldose reductase inhibitor,and is effective for the treatment of sugar cataracts...
T7478 2-Chloro-1-(4-fluorobenzyl)benzimidazole 2-Chloro-1-(4-fluorobenzyl)benzimidazole is an  inhibitor of aldose reductase (ALR2).
TN2295 Vicenin -1 Vicenin-1 possesses potent anti-inflammatory and anti-oxidant activity.
T10393 AT-007 AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and prev...
T15281 Fidarestat Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10, and V301L AKR1B10, respectively). It has the potent...
T16910 Sorbinil Sorbinil is an Aldose reductase inhibitor. Sorbinil plays a therapeutic role in treating diabetes and diabetic complications decreases AR activity and inhibit th...
T17114 Tolrestat Tolrestat is a potent and orally active inhibitor of aldose reductase (IC50: 35 nM).
TN2601 12-O-Methylcarnosic acid 12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibiti...
TN2601 12-O-Methylcarnosic acid 12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibiti...
T1499 Dutasteride Dutasteride is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperplasia.
Danshenol A
TN3760CAS 189308-08-5
Danshenol A has strong aldose reductase (AR) inhibitory activity, has IC50 of 0.10 microM which is comparable to that of epalrestat in clinical use. Danshenol A ...
Gonadorelin Acetate (33515-09-2 free base)
T5015CAS 71447-49-9
Gonadorelin Acetate is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.
Ginsenoside Ro
T3915CAS 34367-04-9
GinsenosideRo exhibits a Ca2+-antagonistic antiplatelet effect.
Tectoridin
T3665CAS 611-40-5
Tectoridin possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflamm...
Ponalrestat
T2013CAS 72702-95-5
Ponalrestat is an aldose reductase inhibitor.
Epalrestat
T1458CAS 82159-09-9
Epalrestat, an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy a...
Isoliquiritigenin
T0725CAS 961-29-5
Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, suppresses aldose reductase (IC50=320 nM).
Finasteride
T0488CAS 98319-26-7
Finasteride is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.
Isocurcumenol
T5S0543CAS 24063-71-6
1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).
Engeletin
T6S0840CAS 572-31-6
1. Engeletin may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engele...
2'-acetylacteoside
T6102CAS 94492-24-7
2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-Ac...
Poliumoside
T6S2384CAS 94079-81-9
Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exhi...
Gonadorelin Acetate (33515-09-2 free base)
T5015CAS 71447-49-9
Gonadorelin Acetate is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.
8-Lavandulylkaempferol
TN3287CAS 883859-83-4
8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase and acetylcholinesterase, res...
Alrestatin
T5195CAS 51411-04-2
Alrestatin is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.
DL-Glyceraldehyde
T4918CAS 56-82-6
Glyceraldehyde is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When p...
BYAKANGELICIN
T5813CAS 482-25-7
BYAKANGELICIN,a main furanocoumarin constituent isolated and characterized as an aldose reductase inhibitor,and is effective for the treatment of sugar cataracts...
2-Chloro-1-(4-fluorobenzyl)benzimidazole
T7478CAS 84946-20-3
2-Chloro-1-(4-fluorobenzyl)benzimidazole is an  inhibitor of aldose reductase (ALR2).
Vicenin -1
TN2295CAS 35927-38-9
Vicenin-1 possesses potent anti-inflammatory and anti-oxidant activity.
AT-007
T10393CAS 2170729-29-8
AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and prev...
Fidarestat
T15281CAS 136087-85-9
Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10, and V301L AKR1B10, respectively). It has the potent...
Sorbinil
T16910CAS 68367-52-2
Sorbinil is an Aldose reductase inhibitor. Sorbinil plays a therapeutic role in treating diabetes and diabetic complications decreases AR activity and inhibit th...
Tolrestat
T17114CAS 82964-04-3
Tolrestat is a potent and orally active inhibitor of aldose reductase (IC50: 35 nM).
12-O-Methylcarnosic acid
TN2601CAS 62201-71-2
12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibiti...
12-O-Methylcarnosic acid
TN2601CAS 62201-71-2
12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibiti...
Dutasteride
T1499CAS 164656-23-9
Dutasteride is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperplasia.