Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis. They include a range of antiviral products used to prevent viral replication in infected cells. Nucleoside analogues can be used against hepatitis B virus, hepatitis C virus, herpes simplex, and HIV. Once they are phosphorylated, they work as antimetabolites by being similar enough to nucleotidesto be incorporated into growing DNA strands.

Gemcitabine
T025195058-81-4
Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis.
  • $34
In Stock
Size
QTY
Sangivamycin
T960518417-89-5
Sangivamycin (NSC-65346) is an effective inhibitor of protein kinase C (PKC, Ki = 10 μM). Sangivamycin exhibits antiproliferative activity against a variety of human cancers.
  • $128
In Stock
Size
QTY
5-BrdU
T679459-14-3
5-BrdU (Broxuridine) , a nucleoside analog, are used in the detection of proliferating cells and competes with thymidine for incorporation into DNA.
  • $34
In Stock
Size
QTY
Decitabine
T15082353-33-5
Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic activity. Decitabine induces cell cycle arrest and apoptosis.
  • $30
In Stock
Size
QTY
5-Fluorouracil
T098451-21-8
5-Fluorouracil (5-FU) is a uracil analog and inhibitor of DNA synthesis, exhibiting antitumor activity by affecting pyrimidine synthesis through thymidylate synthase inhibition; it induces apoptosis and autophagy.
  • $30
In Stock
Size
QTY
Fludarabine
T103821679-14-1
Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation. Fludarabine has antitumor activity and can be used for the treatment of leukemia and lymphoma.
  • $50
In Stock
Size
QTY
TargetMol | Inhibitor Hot
Trifluridine/tipiracil hydrochloride mixture
T3658733030-01-8
Trifluridine tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and tipiracil hydrochloride (TTP) in a 2:1 molar ratio.
  • $33
In Stock
Size
QTY
Cytarabine
T1272147-94-4
Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM). Cytarabine inhibits DNA polymerase and induces cell cycle arrest, autophagy, and apoptosis. Cytarabine has antitumor activity.
  • $30
In Stock
Size
QTY
5-Azacytidine
T1339320-67-2
5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity. 5-Azacytidine regulates gene expression by decreasing the level of DNA methylation. 5-Azacytidine induces autophagy and has antitumor activity.
  • $33
In Stock
Size
QTY
Nelarabine
T6603121032-29-9
Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.
  • $36
In Stock
Size
QTY
Gemcitabine hydrochloride
T6069122111-03-9
Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis.
  • $35
In Stock
Size
QTY
Ascamycin
T1432991432-48-3In house
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces spp. It exhibits selective antibacterial activity against Xanthomonas species, inhibiting Xanthomonas citri, Xanthomonas oryzae, and phage with MIC values of 0.4 μg mL, 12.5 μg mL, and 12.5 μg mL respectively.
  • $350
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Rabacfosadine
T16716859209-74-8In house
Rabacfosadine (GS-9219) is a novel dual pre-drug of the acyclic nucleotide phosphonate PMEG to tumor lymphocytes for the study of lymphoma.
  • $129 TargetMol
In Stock
Size
QTY
Peldesine
T12399133432-71-0In house
Peldesine (BCX 34) is an effective, competitive, reversible, and orally active inhibitor of purine nucleoside phosphorylase. Peldesine inhibits T-cell proliferation with an IC50 of 800 nM. Peldesine can be used in research on cutaneous T-cell lymphoma, psoriasis and HIV infection.
  • $116
In Stock
Size
QTY
Adenosine
T085358-61-7
Adenosine (D-Adenosine) is a natural product, a ribonucleoside consisting of adenine bound to ribose. Adenosine has vasodilatory, antiarrhythmic and analgesic effects.
  • $46
In Stock
Size
QTY
Capecitabine
T1408154361-50-9
Capecitabine (Capecitibine) is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil (5-FU); subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells. FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate for incorporation into the RNA strand.
  • $31
In Stock
Size
QTY
5-Ethynyluridine
T3697169075-42-9
5-Ethynyluridine is a clickable form of uridine.1It is incorporated into cellular RNA, but not DNA, and has been used to detect transcriptionin vitroandin vivo. 1.Jao, C.Y., and Salic, A.Exploring RNA transcription and turnover in vivo by using click chemistryProc. Natl. Acad. Sci. USA105(41)15779-15784(2008)
  • $47
In Stock
Size
QTY
Floxuridine
T096450-91-9
Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.
  • $30
In Stock
Size
QTY
N6-Methyl-2'-O-methyladenosine
TNU035557817-83-1
N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound found on a wide variety of RNA molecules.N6,2′-O-Dimethyladenosine can be used to study obesity and its related diseases.
  • $64
In Stock
Size
QTY
CNDAC hydrochloride
T13621134665-72-8
CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine.
  • $116
In Stock
Size
QTY
Orotic acid
T074665-86-1
Orotic acid (Vitamin B13) is an intermediate product in pyrimidine metabolism.
  • $38
In Stock
Size
QTY
Uridine-5-acetic acid
TNU004620964-06-1
Uridine-5-acetic acid (5-Carboxymethyluridine) is a nucleoside formed during yeast and wheat embryo transfer RNA processes, which can be used for cell labeling and tracking DNA synthesis.
  • $727
In Stock
Size
QTY
Deoxycytidine triphosphate
T75202056-98-6
Deoxycytidine triphosphate is a nucleoside triphosphate.It is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
  • $30
In Stock
Size
QTY
Ganciclovir
T068882410-32-0
Ganciclovir (2'-Nor-2'-deoxyguanosine) is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
  • $51
In Stock
Size
QTY