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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling
MAPK Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library

Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis. They include a range of antiviral products used to prevent viral replication in infected cells. Nucleoside analogues can be used against hepatitis B virus, hepatitis C virus, herpes simplex, and HIV. Once they are phosphorylated, they work as antimetabolites by being similar enough to nucleotidesto be incorporated into growing DNA strands.
Cat. No. Product name CAS No. Purity Chemical Structure
TQ0006 Ethynylcytidine 180300-43-0 98%
Ethynylcytidine is a nucleoside antimetabolite.
TQ0245 Sapacitabine 151823-14-2 98%
Sapacitabine is a nucleoside analog prodrug with antitumor activity.
T5539 GS-443902 1355149-45-9 98%
GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
T15378 Gemcitabine elaidate 210829-30-4 98%
Gemcitabine elaidate, is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential ...
T15235 Enocitabine 55726-47-1 98%
Enocitabine, a nucleoside analog, is a potent DNA replication inhibitor and a DNA chain terminator. Enocitabine inhibits the replication of human cytomegalovirus...
T36572 N6-Methyladenine 443-72-1 98%
N6-Methyladenine is a modified purine commonly found in genomes of prokaryotes, protists, and plants. N6-methyladenine affects diverse DNA functions, including r...
T9726 2’-OMe-Guanosine 2140-71-8 98%
2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.
T9727 2'-Fluoro-2'-Deoxyadenosine 64183-27-3 98%
2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-De...
T36944 Ara-G 38819-10-2 98%
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, wh...
T36866 3-Deazauridine 23205-42-7 98%
3-Deazauridine is a structural analog of uridine that inhibits the biosynthesis of Cytidine-5'-Triphosphate by competitive inhibition of Cytidine Triphosphate sy...
T40192 DGTP 2564-35-4 98%
dGTP is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
T38236 2′-Deoxy-2′-fluoroguanosine 78842-13-4 98%
2′-Deoxy-2′-fluoroguanosine, a nucleoside analog, is a potent inhibitor of influenza virus strains, with an EC90 of <0.35 μM for influenza virus A and B strains....
T38958 DMT-2′Fluoro-dU Phosphoramidite 146954-75-8 98%
DMT-2′Fluoro-dU Phosphoramidite can be used to modify nucleosides.
T38238 2'-Deoxy-2'-fluorocytidine 10212-20-1 98%
2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine ...
T13659 DMTr-LNA-5MeU-3-CED-phosphoramidite 206055-75-6 98%
DMTr-LNA-5MeU-3-CED-phosphoramidite is a nucleoside derivative.
T0010 6-Mercaptopurine 50-44-2 98%
Mercaptopurine is an antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabo...
T38237 2′-O-Methylcytidine 2140-72-9 98%
2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replic...
T20102 8-Azahypoxanthine 2683-90-1 98%
8-Azahypoxanthine is an antimalarial. It inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase.
T19083 1-Methylinosine 2140-73-0 98%
1-Methylinosine is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA.
T10019 1-Methylcytosine 1122-47-0
1-Methylcytosine is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired with isoguanine.
Ethynylcytidine
TQ0006
Ethynylcytidine is a nucleoside antimetabolite.
Sapacitabine
TQ0245
Sapacitabine is a nucleoside analog prodrug with antitumor activity.
GS-443902
T5539
GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
Gemcitabine elaidate
T15378
Gemcitabine elaidate, is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential ...
Enocitabine
T15235
Enocitabine, a nucleoside analog, is a potent DNA replication inhibitor and a DNA chain terminator. Enocitabine inhibits the replication of human cytomegalovirus...
N6-Methyladenine
T36572
N6-Methyladenine is a modified purine commonly found in genomes of prokaryotes, protists, and plants. N6-methyladenine affects diverse DNA functions, including r...
2’-OMe-Guanosine
T9726
2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.
2'-Fluoro-2'-Deoxyadenosine
T9727
2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-De...
Ara-G
T36944
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, wh...
3-Deazauridine
T36866
3-Deazauridine is a structural analog of uridine that inhibits the biosynthesis of Cytidine-5'-Triphosphate by competitive inhibition of Cytidine Triphosphate sy...
dGTP
T40192
dGTP is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
2′-Deoxy-2′-fluoroguanosine
T38236
2′-Deoxy-2′-fluoroguanosine, a nucleoside analog, is a potent inhibitor of influenza virus strains, with an EC90 of <0.35 μM for influenza virus A and B strains....
DMT-2′Fluoro-dU Phosphoramidite
T38958
DMT-2′Fluoro-dU Phosphoramidite can be used to modify nucleosides.
2'-Deoxy-2'-fluorocytidine
T38238
2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine ...
DMTr-LNA-5MeU-3-CED-phosphoramidite
T13659
DMTr-LNA-5MeU-3-CED-phosphoramidite is a nucleoside derivative.
6-Mercaptopurine
T0010
Mercaptopurine is an antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabo...
2′-O-Methylcytidine
T38237
2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replic...
8-Azahypoxanthine
T20102
8-Azahypoxanthine is an antimalarial. It inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase.
1-Methylinosine
T19083
1-Methylinosine is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA.
1-Methylcytosine
T10019
1-Methylcytosine is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired with isoguanine.
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