Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis. They include a range of antiviral products used to prevent viral replication in infected cells. Nucleoside analogues can be used against hepatitis B virus, hepatitis C virus, herpes simplex, and HIV. Once they are phosphorylated, they work as antimetabolites by being similar enough to nucleotidesto be incorporated into growing DNA strands.

Cat. No.	Product name	CAS No.	Purity
T5539	GS-443902	1355149-45-9
T5539	GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
T21052	Lysidine	534-26-9	98%
T21052	Lysidine (2-Methyl-2-iMidazoline) is a nucleoside rarely seen outside of tRNA. Lysidine has better translation fidelity.
T78565	Dihydro-5-azacytidine acetate	2470972-18-8	98%
T78565	Dihydro-5-azacytidine acetate (DHAC), a nucleoside analog, becomes integrated into DNA, thereby inhibiting DNA methylation, and exhibits antitumor activity [1] [...
T79190	Homouridine	30685-57-5	98%
T79190	Homouridine, an analogue of uridine, functions as an intermediate in the synthesis of MMP-2 inhibitor (compound I, IC50 = 150 μM). Moreover, the derivative of ho...
T79198	S-Gem	2169925-98-6	98%
T79198	S-Gem, a thioredoxin reductase (TrxR)-dependent prodrug of Gemcitabine, is selectively activated by TrxR. Studies indicate that S-Gem exhibits lower cytotoxicity...
T82597	DdUTP (lithium), 100mM in H2O		98%
T82597	ddUTP (lithium), at a concentration of 100mM in H20, serves as a nucleotide analog capable of being integrated into DNA, RNA, or other nucleic acids. It is appli...
TQ0006	Ethynylcytidine	180300-43-0	98%
TQ0006	Ethynylcytidine is a nucleoside antimetabolite.
T15378	Gemcitabine elaidate	210829-30-4	98%
T15378	Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with ...
TQ0245	Sapacitabine	151823-14-2	98%
TQ0245	Sapacitabine is a nucleoside analog prodrug with antitumor activity.
T0964	Floxuridine	50-91-9	99.96%
T0964	Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.
T1600	Doxifluridine	3094-09-5	99.96%
T1600	Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridi...
T0010	6-Mercaptopurine	50-44-2	99.94%
T0010	6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting puri...
TNU0187	2',5-Difluoro-2'-deoxy-1-arabinosyluracil	69123-95-1	99.94%
TNU0187	2',5-Difluoro-2'-deoxy-1-arabinosyluracil (2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine) is a urinary pyrimidine nucleoside analogue with potential antiepileptic a...
T19382	Isoguanine	3373-53-3	99.93%
T19382	Isoguanine is a purine base that is an isomer of guanine. A building block in organic synthesis.
T0746	Orotic acid	65-86-1	99.93%
T0746	Orotic acid (Vitamin B13) is an intermediate product in pyrimidine metabolism.
T1272	Cytarabine	147-94-4	99.92%
T1272	Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM). Cytarabine inhibits DNA polymerase and induces cell cycle arrest, autophag...
T40192	DGTP	2564-35-4	99.9%
T40192	dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8...
T1591L	Cytidine	65-46-3	99.85%
T1591L	Cytidine (Cytosine-1-β-D-ribofuranoside) is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond. Cytidine is a precurso...
T6069	Gemcitabine hydrochloride	122111-03-9	99.85%
T6069	Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor an...
TNU0007	3'-Deoxy-3'-fluoroadenosine	75059-22-2	99.84%
TNU0007	3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with a wide range of anti-tumor and anti-viral activity, and has inhibitory effects on tick-borne enc...