Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis. They include a range of antiviral products used to prevent viral replication in infected cells. Nucleoside analogues can be used against hepatitis B virus, hepatitis C virus, herpes simplex, and HIV. Once they are phosphorylated, they work as antimetabolites by being similar enough to nucleotidesto be incorporated into growing DNA strands.

Cat. No.	Product name	CAS No.	Purity
TQ0245	Sapacitabine	151823-14-2	98%
TQ0245	Sapacitabine is a nucleoside analog prodrug with antitumor activity.
T5539	GS-443902	1355149-45-9	98%
T5539	GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
T15378	Gemcitabine elaidate	210829-30-4	98%
T15378	Gemcitabine elaidate, is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential ...
TQ0006	Ethynylcytidine	180300-43-0	98%
TQ0006	Ethynylcytidine is a nucleoside antimetabolite.
T36944	Ara-G	38819-10-2	98%
T36944	Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, wh...
T9726	2’-OMe-Guanosine	2140-71-8	98%
T9726	2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.
T38958	DMT-2′Fluoro-dU Phosphoramidite	146954-75-8	98%
T38958	DMT-2′Fluoro-dU Phosphoramidite can be used to modify nucleosides.
T9727	2'-Fluoro-2'-Deoxyadenosine	64183-27-3	98%
T9727	2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-De...
T38238	2'-Deoxy-2'-fluorocytidine	10212-20-1	98%
T38238	2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine ...
TNU0839	1,4-Dideoxy-1,4-epithio-D-ribitol	190315-43-6	98%
TNU0839	1,4-Dideoxy-1,4-epithio-D-ribitol is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of ant...
T20102	8-Azahypoxanthine	2683-90-1	98%
T20102	8-Azahypoxanthine is an antimalarial. It inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase.
T36866	3-Deazauridine	23205-42-7	98%
T36866	3-Deazauridine is a structural analog of uridine that inhibits the biosynthesis of Cytidine-5'-Triphosphate by competitive inhibition of Cytidine Triphosphate sy...
T19083	1-Methylinosine	2140-73-0	98%
T19083	1-Methylinosine is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA.
TNU0436	2-Thiocytidine	13239-97-9	98%
TNU0436	2-Thiocytidine is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and has a broad spectrum of antitumor activity.2-Thiocyt...
T14329	Ascamycin	91432-48-3	98%
T14329	Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces spp. It shows selective antibacterial activity against Xanthomonas species and...
T38237	2′-O-Methylcytidine	2140-72-9	98%
T38237	2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replic...
T38236	2′-Deoxy-2′-fluoroguanosine	78842-13-4	98%
T38236	2′-Deoxy-2′-fluoroguanosine, a nucleoside analog, is a potent inhibitor of influenza virus strains, with an EC90 of <0.35 μM for influenza virus A and B strains....
T36971	5-Ethynyluridine	69075-42-9	98%
T36971	5-Ethynyluridine is a clickable form of uridine.1It is incorporated into cellular RNA, but not DNA, and has been used to detect transcriptionin vitroandin vivo. ...
T4061	LY2334737	892128-60-8	98%
T4061	LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.
T7319	7-Methylguanosine	20244-86-4	98%
T7319	7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor (IC50 : 87.8 ± 7.5 μM).