T11056 |
DLK-IN-1
|
1620574-24-4
|
98%
|
|
DLK-IN-1 is a selective oral active inhibitor of bisleucine zipper kinase (DLK, MAP3K12) with Ki of 3 nM. DLK-IN-1 is active in the Alzheimer's disease model, re...
|
T11440 |
GNE-8505
|
1620573-48-9
|
98%
|
|
GNE-8505 is an orally available inhibitor of Dual leucine zipper kinase (DLK).
|
T12813L |
Seco-Duocarmycin SA
|
144667-38-9
|
98%
|
|
Seco-Duocarmycin SA is a highly potent DNA alkylator used as an ADC cytotoxin.
|
T19300 |
Duocarmycin Analog
|
372954-15-9
|
98%
|
|
Duocarmycin Analog is used as an DNA alkylator and ADC cytotoxin. Duocarmycin Analog is an analog of Duocarmycin.
|
T2495 |
Lomeguatrib
|
192441-08-0
|
99.62%
|
|
Lomeguatrib, a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) .
|
T21297 |
Miriplatin hydrate
|
250159-48-9
|
99.6%
|
|
Miriplatin hydrate (MPT) is a novel platinum complex used in TACE that shows promise for the treatment of hepatocellular carcinoma (HCC). Miriplatin hydrate is a...
|
T3707 |
GNE-3511
|
1496581-76-0
|
99.37%
|
|
GNE-3511 is a potent and selective dual leucine zipper kinase inhibitors.
|
T11120 |
Duocarmycin TM
|
157922-77-5
|
99.15%
|
|
Duocarmycin TM is a DNA alkylator. Duocarmycin TM is an exceptionally potent antitumor antibiotic.
|
T1507 |
Streptozocin
|
18883-66-4
|
98.89%
|
|
Streptozotocin is an antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animal...
|
T15771 |
Lobaplatin
|
135558-11-1
|
98.00%
|
|
Lobaplatin (D-19466) is a diastereometric mixture of platinum(II) complexe. Lobaplatin (D-19466) is a third-generation platinum anti-neoplastic agent which shows...
|
T7539 |
O6-Benzylguanine
|
19916-73-5
|
98%
|
|
O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.
|
T17159 |
Treosulfan
|
299-75-2
|
98%
|
|
Treosulfan is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types.
|
T1250 |
Thio-TEPA
|
52-24-4
|
98%
|
|
Thiotepa is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.
|
T7221 |
Satraplatin
|
129580-63-8
|
98%
|
|
Satraplatin is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical activity against...
|
T4350 |
Palifosfamide
|
31645-39-3
|
97%
|
|
Palifosfamide lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The IC50 ranges from 2.25 to...
|
T17212 |
VAL-083
|
23261-20-3
|
|
|
VAL-083 is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.
|
T3091 |
Carmustine
|
154-93-8
|
98%
|
|
Carmustine is a cell-cycle phase nonspecific alkylating antineoplastic agent.
|
T0923 |
Busulfan
|
55-98-1
|
98%
|
|
Busulfan is a synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully understood,...
|
T1241 |
Altretamine
|
645-05-6
|
98%
|
|
Altretamine is an alkylating agent with antineoplastic activity.
|
T9985 |
Methyl methanesulfonate
|
66-27-3
|
98%
|
|
Methyl methanesulfonate is a DNA alkylator that modifies adenine (3-methyladenine) and guanine (7-methyladenine) respectively, resulting in base mismatch and rep...
|