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DNA

Deoxyribonucleic acid (DNA) is a molecule composed of two polynucleotide chains that coil around each other to form a double helix carrying genetic instructions for the development, functioning, growth and reproduction of all known organisms and many viruses. DNA and ribonucleic acid (RNA) are nucleic acids. Alongside proteins, lipids and complex carbohydrates (polysaccharides), nucleic acids are one of the four major types of macromolecules that are essential for all known forms of life.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T4187 Gemcitabine monophosphate sodium salt hydrate 1638288-31-9
Gemcitabine monophosphate sodium salt hydrate
Gemcitabine monophosphate disodium salt is a monophosphate derivative of Gemcitabine.
T73719 Azoxymethane 25843-45-2 98%
Azoxymethane
Azoxymethane (AOM) is a DNA damaging agent that induces cancer and can be used in mouse models of colorectal cancer.
T7031 Aristolochic acid B 475-80-9 99.99%
Aristolochic acid B
Aristolochic acid B (Aristolochic Acid II) is one of the major components of the carcinogenic plant extract aristolochic acid, is known to be mutagenic and to fo...
T0951 Hydroxychloroquine sulfate 747-36-4 99.87%
Hydroxychloroquine sulfate
Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malari...
T5486 RU.521 2262452-06-0 99.82%
RU.521
RU.521 (RU3205217) is a potent dsDNA inhibitor (IC50 : 700 nM), inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS.
T3103 L67 325970-71-6 99.79%
L67
L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).
T0377 Clofazimine 2030-63-9 99.79%
Clofazimine
Clofazimine (NSC-141046) is a phenazine dye with anti-mycobacterial and anti-inflammatory activities. Clofazimine has a slow bactericidal effect on Mycobacterium...
T0942 Quinacrine dihydrochloride 69-05-6 99.72%
Quinacrine dihydrochloride
Quinacrine dihydrochloride (Mepacrine dihydrochloride) is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic and...
T4517 L189 64232-83-3 99.72%
L189
L189 is a human DNA ligase inhibitor, inhibits hLigI/III/IV (IC50: 5/9/5 μM).
T0707 Cyclophosphamide hydrate 6055-19-2 99.65%
Cyclophosphamide hydrate
Cyclophosphamide hydrate is a DNA alkylating agent, an inhibitor of DNA synthesis. Cyclophosphamide hydrate has antitumor and immunosuppressive activities.
T0438 Proflavine Hemisulfate 1811-28-5 99.55%
Proflavine Hemisulfate
Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt form of proflavine, an acridine-derived fluorescent contrast and disinfectant ag...
T1548 Methoxsalen 298-81-7 99.47%
Methoxsalen
Methoxsalen (NCI-C55903) is a Photoactivated Radical Generator and Psoralen. The mechanism of action of methoxsalen is as a Photoabsorption. The physiologic effe...
T77563 4-Ethylcatechol 1124-39-6 99.38%
4-Ethylcatechol
4-Ethylcatechol is present in red wine and can be extracted from Glechoma longituba (NaKai) Kupr.4-Ethylcatechol induces DNA damage in the presence of Cu(II).4-E...
T67892 BTB09089 245728-44-3 99.31%
BTB09089
BTB09089 (GPR65 agonist ) is a T cell death-associated gene 8 (TDAG8/GPR65)-specific agonist.BTB09089 induces TDAG8 expression and regulates cytokine production ...
TN2143 3,7,4'-Trihydroxyflavone 2034-65-3 99.16%
3,7,4'-Trihydroxyflavone
3,7,4'-Trihydroxyflavone(5-Deoxykampferol) is a DNA-breaking flavonoid isolated from rosewood heartwood. It inhibits osteoclast differentiation, actin ring forma...
T60753 L82 329227-30-7 99.07%
L82
L82 is a DNA ligase 1 (DNA Lig1) inhibitor (hLig1 IC50=12 μM) that is selective and non-competitive.L82 expresses anti-proliferative activity against breast canc...
T30745L Carboxy-pyridostatin 2HCl 99%
Carboxy-pyridostatin 2HCl
Carboxy-pyridostatin 2HCl has potential antitumor activity with high affinity for DNA at DNA G4s.
T4024 Norharmane 244-63-3 98.76%
Norharmane
Norharmane (β-Carboline) is a natural β-carboline first isolated from plants of the Zygophyllaceae family.
T68151L Tallimustine HCl 118438-45-2 98.52%
Tallimustine HCl
Tallimustine HCl is a DNA inhibitor, an AT-specific alkylated antitumor derivative of diamycin.Tallimustine HCl can be used in severe combined immunodeficiency m...
T0707L Cyclophosphamide 50-18-0 98.26%
Cyclophosphamide
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
Gemcitabine monophosphate sodium salt hydrate
T4187
Gemcitabine monophosphate disodium salt is a monophosphate derivative of Gemcitabine.
Azoxymethane
T73719
Azoxymethane (AOM) is a DNA damaging agent that induces cancer and can be used in mouse models of colorectal cancer.
Aristolochic acid B
T7031
Aristolochic acid B (Aristolochic Acid II) is one of the major components of the carcinogenic plant extract aristolochic acid, is known to be mutagenic and to fo...
Hydroxychloroquine sulfate
T0951
Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malari...
RU.521
T5486
RU.521 (RU3205217) is a potent dsDNA inhibitor (IC50 : 700 nM), inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS.
L67
T3103
L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).
Clofazimine
T0377
Clofazimine (NSC-141046) is a phenazine dye with anti-mycobacterial and anti-inflammatory activities. Clofazimine has a slow bactericidal effect on Mycobacterium...
Quinacrine dihydrochloride
T0942
Quinacrine dihydrochloride (Mepacrine dihydrochloride) is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic and...
L189
T4517
L189 is a human DNA ligase inhibitor, inhibits hLigI/III/IV (IC50: 5/9/5 μM).
Cyclophosphamide hydrate
T0707
Cyclophosphamide hydrate is a DNA alkylating agent, an inhibitor of DNA synthesis. Cyclophosphamide hydrate has antitumor and immunosuppressive activities.
Proflavine Hemisulfate
T0438
Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt form of proflavine, an acridine-derived fluorescent contrast and disinfectant ag...
Methoxsalen
T1548
Methoxsalen (NCI-C55903) is a Photoactivated Radical Generator and Psoralen. The mechanism of action of methoxsalen is as a Photoabsorption. The physiologic effe...
4-Ethylcatechol
T77563
4-Ethylcatechol is present in red wine and can be extracted from Glechoma longituba (NaKai) Kupr.4-Ethylcatechol induces DNA damage in the presence of Cu(II).4-E...
BTB09089
T67892
BTB09089 (GPR65 agonist ) is a T cell death-associated gene 8 (TDAG8/GPR65)-specific agonist.BTB09089 induces TDAG8 expression and regulates cytokine production ...
3,7,4'-Trihydroxyflavone
TN2143
3,7,4'-Trihydroxyflavone(5-Deoxykampferol) is a DNA-breaking flavonoid isolated from rosewood heartwood. It inhibits osteoclast differentiation, actin ring forma...
L82
T60753
L82 is a DNA ligase 1 (DNA Lig1) inhibitor (hLig1 IC50=12 μM) that is selective and non-competitive.L82 expresses anti-proliferative activity against breast canc...
Carboxy-pyridostatin 2HCl
T30745L
Carboxy-pyridostatin 2HCl has potential antitumor activity with high affinity for DNA at DNA G4s.
Norharmane
T4024
Norharmane (β-Carboline) is a natural β-carboline first isolated from plants of the Zygophyllaceae family.
Tallimustine HCl
T68151L
Tallimustine HCl is a DNA inhibitor, an AT-specific alkylated antitumor derivative of diamycin.Tallimustine HCl can be used in severe combined immunodeficiency m...
Cyclophosphamide
T0707L
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
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TargetMol