stabilizing — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T79508	Microtubule stabilizing agent-1
	Compound 3l, a paclitaxel derivative known as Microtubule Stabilizing Agent-1, effectively enhances tubulin polymerization and demonstrates antitumor efficacy [1].
T7964	Isomalt	Palatinitol,Palatinit	Others , Dehydrogenase
	Isomalt (Palatinitol) is a mixture of 1,6-mannitol glucopyranoside and 1,6-sorbitol glucopyranoside		Others , Dehydrogenase
T3253	Castor oil	Ricinus Oil,Xenaderm,Venelex	Others
	Castor oil (Xenaderm) is a vegetable oil pressed from the seeds of the castor bean, Ricinus communis, used as a laxative and as an excipient in medicinally.		Others
T7806	Licarbazepine	10,11-hydroxy-10,11 Dihydrocarbamezer	Others
	Licarbazepine (10,11-hydroxy-10,11 Dihydrocarbamezer) is the pharmacologically active metabolite of oxcarbazepine, a drug indicated for the treatment of partial seizures and bipolar disorders.		Others
T9409	Mesdopetam hemitartrate	IRL790 hemitartrate,1-Propanamine, N-[2-[3-fluoro-5-(methylsulfonyl)phenoxy]ethyl]-, (2R,3R)-2,3-dihydroxybutanedioate (2:1)	Dopamine Receptor
	Mesdopetam hemitartrate (IRL790 hemitartrate) is an antagonist of dopamine D3 receptor (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor). It has psychomotor stabilizing properties.		Dopamine Receptor
T74166	Microtubule destabilizing agent-1
	Microtubule destabilizing agent-1 (Compound 12b), a hydroxamic acid-based microtubule destabilizing agent (MDA), exhibits potent antitumor activity, favorable metabolic stability, and high bioavailability, making it a pr...
TQ0013	BTTAA		Others
	BTTAA, a Cu(I)-stabilizing ligand, performs potently with ubiquitin Glu18AzF.		Others
T6490	Epothilone A	epothile,Epo A	Apoptosis , Microtubule Associated
	Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM.		Apoptosis , Microtubule Associated
T11147	EC5026	BPN-19186	Epoxide Hydrolase
	EC5026 (BPN-19186) has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators.		Epoxide Hydrolase
T5938	4-Phenoxybenzylamine		HCV Protease
	4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .		HCV Protease
T7409	360A		DNA/RNA Synthesis , Telomerase
	360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).		DNA/RNA Synthesis , Telomerase
T1170	Olopatadine hydrochloride	Olopatadine HCl,KW4679,ALO4943A	5-HT Receptor , Histamine Receptor
	Olopatadine hydrochloride (ALO4943A) is an antihistamine with mast-cell stabilizing properties used as eye drops in the treatment of ALLERGIC CONJUNCTIVITIS.		5-HT Receptor , Histamine Receptor
T16674	Pseudouridine		Endogenous Metabolite
	Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure.		Endogenous Metabolite
T13951	UCB-9260		TNF
	UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.		TNF
T21470L	Davunetide acetate	Davunetide acetate(211439-12-2 Free base)	Beta Amyloid , Microtubule Associated
	Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS. Davunetide acetate is a microtubule-stabilizing peptide and inhibits Aβ aggregation and Aβ-induced neurotoxicit...		Beta Amyloid , Microtubule Associated
T24239	K201	K-201,JTV 519,JTV-519,K 201	Calcium Channel
	K201 (JTV-519) is a Ca2+-dependent blocker and prevents abnormal Ca(2+) leak from the sarcoplasmic reticulum in the ischemic heart and skeletal muscle (SkM) by stabilizing the ryanodine receptors.		Calcium Channel
T9095	Necrostatin-34	2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4	RIP kinase
	Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain.		RIP kinase
T77516	SARS-CoV-2-IN-39		Antiviral , SARS-CoV
	SARS-CoV-2-IN-39 is a SARS-CoV-2 inhibitor with an EC50 of 1 μM. SARS-CoV-2-IN-39 has antiviral activity and inhibits SARS-CoV-2 by inhibiting SKP2 protein and stabilizing BECN1.		Antiviral , SARS-CoV
T5S1989	Apiin	Apioside	Others
	1. Apiin (Apioside) is the reducing and stabilizing agent. 2. Apiin has inhibitory activity in-vitro on iNOS expression and nitrite production when added before LPS stimulation in the medium of J774.A1 cells.		Others
T1282	Carteolol hydrochloride	Arteoptic,Abbott-43326,OPC-1085 hydrochloride,Carteolol HCl,Mikelan	Adrenergic Receptor
	Carteolol hydrochloride (Abbott-43326) is a synthetic quinolinone derivative, antihypertensive Carteolol Hydrochloride is a nonselective beta-adrenoceptor blocking agent for beta-1 and beta-2 receptors with no membrane-s...		Adrenergic Receptor