non-toxic

CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.

Gut restricted-7 (GR-7) is a covalent and orally active pan-bile salt hydrolase (BSH) inhibitor that reduces gut bacterial BSHs and decreases deconjugated bile acid levels in the feces of mice.

Metacetamol (3-Acetamidophenol) is a derivative of acetaminophen, a non-toxic regional isomer of acetaminophen. It is an over-the-counter analgesic and antipyretic and is also used as an organic synthesis intermediate.

Cefodizime is a new cephalosporin antibiotic with a wide range of biological activities.Cefodizime is non-toxic to the kidneys and is well tolerated with immunomodulatory activity.Cefodizime has antimicrobial activity and is used in the study of serious infections of the respiratory and urinary systems.

Sodium carboxymethyl cellulose (CMC-Na) (Viscosity:800-1200 mPa.s) is a water-soluble cellulose, commonly used as a co-solvent in animal experiments, and is essentially non-toxic to animals.

Methylcellulose, a natural polymer, is non-toxic and forms gels upon heating.

Ethylmalonic acid is potentially toxic, non-carcinogenic, and has been associated with anorexia nervosa and methoxy decarboxylase deficiency.

Copper(II) gluconate is a non-toxic copper supplement. As a precursor catalyst, it can be used for photoinduced polymerization of acrylates.

3,3',4,4'-Benzophenonetetracarboxylic dianhydride is a compound used as a polyimide precursor in the production of polyimide films and adhesives. It is a non-toxic material with no known adverse effects on human health.

DIQ3 is non-toxic to normal human cell lines and is an effective anti-cancer agent.

Hepln-13 is a hepsin inhibitor that acts by hindering prostate cancer bone metastasis.

LV-320 is a potent, uncompetitive ATG4B inhibitor with an IC50 of 24.5 μM and a Kd of 16 μM. LV-320 inhibits ATG4B enzymatic activity, blocks autophagic flux in cells, and is stable, non-toxic, and active in vivo. These findings suggest that LV-320 will serve as a relevant chemical tool to study the various roles of ATG4B in cancer and other contexts [1].

Macitentan-d4 (ACT-064992 D4) is a deuterated substitute for Macitentan and can be used as a dual antagonist of the non-peptides ETA and ETB (endothelin receptor).Macitentan-d4 is less toxic than Macitentan, has a longer half-life, and can be used to study endothelin receptor-mediated diseases.

Reversan(CBLC4H10), a small molecule inhibitor that acts on multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (Pgp), has been found to improve the efficacy of chemotherapy for glioblastoma, with the advantages of being highly effective and non-toxic.

Chlorazanil, a triazine derivative, is a new, orally effective, non-toxic diuretic that inhibits sodium and chloride absorption in the distal tubule.

Aripiprazole lauroxil, the N-acyloxymethyl prodrug form of aripiprazole, a long-acting injectable (LAI) antipsychotic. Aripiprazole lauroxil is cleaved by esterases in vivo to N-hydroxymethyl aripiprazole (lauric acid), which is then cleaved to aripiprazole, which is non-toxic.

ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM. ITX3 has anticancer effects, inhibits trion mediated GTP exchange on RhoG and Rac1, inhibits NGF-mediated neurite growth in PC12 cells and REF52 fibroblast structure formation induced by trion.

Lactimidomycin, isolated from Streptomyces, is an inhibitor of eukaryotic translation elongation. It is also a potent and non-toxic inhibitor of dengue virus 2 and other RNA viruses. Lactimidomycin has an antiproliferative effect on tumor cell lines. It i

Mivotilate, a potent, non-toxic aryl hydrocarbon receptor (AhR) activator, functions as a hepatoprotective agent.

Hesperidin dihydrochalcone, a non-toxic sweetener with high sweetness and low calories, exhibits multiple biological activities including anti-oxidation, liver and kidney protection, bacteriostasis, and enhancement of gastrointestinal health.

TMB(dihydrochloride x.hydrate) is the dihydrochloride salt and hydrate form of TMB. It is a non-toxic and non-mutagenic colorless dye used as a chromogenic agent in horseradish peroxidase-based assay systems. This compound also serves as a photoacoustic probe for reactive oxygen and nitrogen species (ROS RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce a blue oxidized product. Additionally, TMB(dihydrochloride x.hydrate) can detect singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922.

hAChE-IN-9 (compound 7i) is a selective inhibitor of human acetylcholinesterase (hAChE), showcasing inhibition activities with IC50 values of 0.05 μM for AChE and 2.85 μM for BChE. This compound modulates toxic Aβ oligomers into non-toxic forms and offers antioxidant and neuroprotective effects against Aβ-induced toxicity. hAChE-IN-9 is employed in the study of Alzheimer's disease.

DSPE-PEG(2000)-COOH, a 1,2-distearoyl-sn-glycero-3-PE (DSPE) derivative modified by PEGylation and carboxylation, is a non-toxic and biodegradable amphiphilic copolymer that can be used to form micelles to deliver nanoparticles.

The compound Sodium Glucoheptonate (H-Quest A300), also known as Sodium Glucoheptonate, is a non-toxic and harmless chelating agent capable of forming stable complexes with divalent and trivalent metal ions such as Ca2+, Fe2+, Fe3+, and Al3+.