d serine

D-Serine ((R)-Serine), an endogenous amino acid, is a potent co-agonist at the NMDA glutamate receptor.

N-Cbz-D-serine Methyl Ester is a useful organic compound for research related to life sciences. The catalog number is T66377 and the CAS number is 93204-36-5.

2-[O-(2-Azidoethyl)-D-serine]-cyclosporin A (Compound 33) is a derivative of Cyclosporine. This compound exhibits an IC50 of 0.11 μg/mL in mixed lymphocyte reaction assays.

1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine-d62ammonium (1,2-POPS-d62ammonium) is the deuterium-labeled form of 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine ammonium.

1,2-Dioleoyl-sn-glycero-3-phospho-L-serine-d62ammonium (DOPS-NH3-d62) is the deuterium-labeled ammonium form of 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine.

[1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine-d3(1,2-POPS-d3) ammonium] is a deuterium-labeled form of 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine ammonium.

1-Palmitoyl-2-stearoyl-sn-glycero-3-phospho-L-serine-d66ammonium (PSPS-d66ammonium) is the deuterium-labeled form of 1-Palmitoyl-2-stearoyl-sn-glycero-3-phospho-L-serine ammonium.

(2S,8R,19Z)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine-d3ammonium ((2S,8R,19Z)DOPS-d3ammonium) is the deuterium-labeled version of (2S,8R,19Z)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine ammonium. The sodium salt variant, 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA), serves as a substitute for phosphatidylserine (phospholipid L-serine). It can be used in conjunction with DOPC and DOPE in lipid mixtures to synthesize liposomes. This compound can self-assemble into monolayer or bilayer membrane structures with properties similar to those of cell membranes, featuring high membrane fluidity and flexibility. It finds extensive application in membrane biology, cell membrane research, liposome preparation, and drug delivery systems.

1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine-d3ammonium (18:2 PS-d3ammonium) is a deuterium-labeled form of 1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine ammonium.

MKI-1 (MASTL Kinase Inhibitor-1) is an inhibitor of MASTL (microtubule-associated serine/threonine kinase-like, IC50= 9.9 μM). MKI-1 exerts radiosensitizer and antitumor activities through PP2A activation in breast cancer.

DMNB-caged-Serine is a photocaged amino acid, with DMNB as a blue light-sensitive caging group. It can be incorporated into proteins in Saccharomyces cerevisiae in response to the amber nonsense codon (TAG), facilitating control over the chemical composition of mammalian proteins.

D-(-)-3-Phosphoglyceric acid disodium (3-Phospho-D-glyceric acid disodium) is an intermediate in glycolysis/gluconeogenesis and the biosynthesis of serine, glycine, and threonine, competitively inhibiting yeast enolase. It also functions as an intermediate in biosynthetic pathways in plants, eukaryotes, and prokaryotes.

BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), demonstrating 3.4- and 200-fold greater efficacy compared to trypsin, respectively.

BCX 1470 hydrochloride is a potent serine protease inhibitor with anti-inflammatory activity that inhibits the ester hydrolysis and haemolytic activity of factor D and C1s, and can be used to study oedema.

D-(+)-Xylose (Wood sugar) is an aldopentose - a monosaccharide containing five carbon atoms and an aldehyde functional group. It has chemical formula C5H10O5 and is 40% as sweet as sucrose. Xylose is also found in mucopolysaccharides of connective tissue and sometimes in the urine. Xylose is the first sugar added to serine or threonine residues during proteoglycan type O-glycosylation. Therefore xylose is involved in the biosythetic pathways of most anionic polysaccharides such as heparan sulphate and chondroitin sulphate. In medicine, xylose is used to test for malabsorption by administering a xylose solution to the patient after fasting. If xylose is detected in the blood and/or urine within the next few hours, it has been absorbed by the intestines. Xylose is said to be one of eight sugars which are essential for human nutrition, the others being galactose, glucose, mannose, N-acetylglucosamine, N-acetylgalactosamine, fucose, and sialic acid. . Xylose in the urine is a biomarker for the consumption of apples and other fruits.

Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions, including mitochondrial cysteine desulfurase, cystathionine γ-synthase, various aminotransferases, and a d-serine dehydratase.

DL-Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2.

2-Chloromethyl-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one targets the Neutrophil elastase (human).

Acein acetate is a high-affinity angiotensin-converting enzyme (ACE) ligand (Kd = 2.79 nM). Concentrations up to 500 nM had no significant effect on ACE enzyme activity. Enhanced NMDA + D-serine-induced dopamine release from striatal slices in vitro and striatum in vivo.

D,L-Cystathionine dihydrochloride is an intermediate in the synthesis of cysteine, which acts from the isotype of cysteine-β-synthase (CBS) produced by leucine and serine. Derived from cysteine. DL-cysteine contains a cysteine (βC-S) carbon-sulfur bond.

FD-IN-1 (Compound 12) is an orally active Factor D (FD) inhibitor (IC50=12 nM) that also inhibits Factor XIa (FXIa) and Tryptase β2 with IC50 values of 7.7 and 6.5 μM, respectively.

BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), exhibiting 3.4- and 200-fold greater efficacy than trypsin, respectively.

CID 2011756 is an ATP-competitive and specific PKD1 inhibitor.

kb NB 142-70 is a selective protein kinase D (PKD) inhibitor with IC50 values of 28.3 nM, 58.7 nM, and 53.2 nM for PKD1, PKD2, and PKD3 respectively.