ch 1

NIOCH 14 is an orally available antiviral compound that inhibits external keratovirus, poxvirus, and smallpox virus.

Sch 18099 showed anthelmintic activity.

CH 102 is an isoquinoline derivative that inhibits platelet aggregation.

CH 150 is a bio-active chemical.

CH 141 is a new type of peripheral vasodilator.

Sch 13835 is an inhibitor of platelet derived growth factor.

Notch 1 TFA encodes a member of the NOTCH family of proteins.

SCH 12223 is a unique drug that protects the stomach and intestinal epithelium from harmful irritation.

D-Lactate dehydrogenase (D-LDH), an oxidoreductase, catalyzes the oxidation of D-lactate to pyruvate leveraging NAD+ or NADP+ as acceptors and acting on the donor CH-OH group. Predominantly found in bacteria and fungi, it is frequently utilized in biochemical research [1].

CH-0793076 (TP3076) TFA, a hexacyclic camptothecin analog, is active drug and major metabolite of TP300. CH-0793076 TFA inhibits DNA topoisomerase I with an IC 50 of 2.3 μM. CH-0793076 TFA is efficacious against cells expressing BCRP (breast cancer resistance protein) [1] .

Ch55-O-C3-NH2, also known as RAR ligand 1, is a ligand derived from the Ch55 compound that specifically targets RAR. Through a linker, Ch55-O-C3-NH2 interacts with cIAP1 ligand Bestatin to form SNIPER[1].

CHIKV nsP2 protease-IN-1 (compound J13) is an orally active inhibitor of non-structural protein 2 protease (non-structural protein 2protease), exhibiting an EC50 value of 0.39 μM against CH S27. This compound is utilized in the research of Chikungunya virus.

SU 4029 dihydrochloride is a bioactive chemical.

Tubulin HDAC-IN-1 is a dual inhibitor of tubulin and HDAC8, interacting with tubulin via CH π interactions and with HDAC8 through hydrogen bonds. It effectively inhibits tubulin polymerization and selectively targets HDAC8 with an IC50 of 150 nM. Additionally, Tubulin HDAC-IN-1 demonstrates cytotoxicity against various human cancer cells, induces cell cycle arrest in the G2 M phase, and triggers cell apoptosis, making it valuable for studying hematologic and solid tumors, including neuroblastoma and leukemia [1].