anthelmintic

Hexylresorcinol (4-Hexylresorcinol) is a substituted dihydroxybenzene utilized topically as an antiseptic for minor skin infection treatment.

α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.

CGP 20376 is a benzothiazole compound, an anthelmintic, with dual dose-dependent modulation of in vitro effects on the respiratory burst of eosinophils and antifibrillatory properties.

CMP-5 2HCl is a anthelmintic agent. CMP-5 2HCl shows EC100 of 5μM against H. contortus in vitro.

Monepantel (AAD1566) is an organic anthelmintic and nicotinic acetylcholine receptor antagonist from roundworms and esophagostomies that is widely used for de-worming in agriculture and livestock.

Brotianide (BAY-VA4059) has anthelmintic activity and is highly potent against liver fluke and gastric fluke infestations and can be used to treat acute, subacute and chronic liver fascioliasis infections in sheep.

Dymanthine (ADMA 18) is an agent of veterinary anthelmintic.

Febantel is an anthelmintic. It is used for veterinary use on dogs, cats, cattle, sheep, goats, pig, and poultry against roundworms and tapeworms.

Phenothiazine (ENT 38) is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Phenothiazines antagonize the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain, potentially preventing chemotherapy-induced emesis.

(1R)-α-Pinene ((+)-alpha-Pinene) is a volatile substance from plants with antimicrobial activity and anthelmintic activity that reduces the growth of Bacillus cereus populations.

Selamectin (UK-124114) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. In an H. contortus larval development assay, selamectin (0.1 μg ml) shows the effect of growth inhibition.

Closantel (R-31520), a salicylanilide anthelmintic compound, shows different anthelmintic spectra and obvious toxicity in mammals.

Oxfendazole (RS-8858), a broad spectrum benzimidazole anthelmintic, protects livestock against roundworm, strongyles and pinworms.

Eprinomectin (MK-397) is an avermectin with anthelmintic and insecticidal activities.

Ascaridole (NSC-406266) acts as an anthelmintic compound that repels parasitic helminths (worms) in humans and plants and has weak antimalarial activity.

Oxyclozanide (Oxyclozanid) is a salicylanilide anthelmintic used in grazing animals for fasciola and cestode infestations.

Nitazoxanide (NSC-697855) is a synthetic benzamide with antiprotozoal activity. Nitazoxanide exerts its antiprotozoal activity by interfering with the pyruvate ferredoxin flavodoxin oxidoreductase dependent electron transfer reaction.

Flubendazole (Flumoxane) is available OTC in Europe that is an anthelmintic using to treat worm infection in humans.

Moxidectin (CL301423) is an anthelmintic drug which kills parasitic worms, and is used for the prevention and control of heartworm and intestinal worms. It can be found in treatments prescribed for animals such as dogs, cats, horses, cattle and sheep. Application methods for moxidectin vary by treatment, and include oral, topical, and injectable solutions. Cydectin Pour On is a trade name for a formulation for use on cattle and red deer.

Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.

Nitroxynil (4-Hydroxy-3-iodo-5-nitrobenzonitrile) is an anthelmintic compound that effectively targets parasites in both adult and immature stages. It is extensively employed in investigations pertaining to Fasciola hepatica infection.

8-Hydroxyquinoline hemisulfate (Oxyquinoline sulfate) is an antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action

Dichlorophen (DDM) is a nontoxic laxative vermicide of chlorinated phenol compound. Dichlorophen is used as a veterinary fungicide, anthelmintic, and anti-protozoan, as well as an ingredient in antimicrobial soaps and shampoos. This agent probably acts by increasing the clearing of intestinal contents, thereby eradicating tapeworm infections from the intestines.

Piperazine adipate (Piperazine adipate) is a highly effective broad-spectrum anthelmintic that works by causing paralysis in parasitic worms.