Ketone

Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8.

Dilinoleyl Ketone (Bis(linoleyl) ketone) is a lipid membrane that is a potential carrier of nucleic acids.

N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride (N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride) is an inhibitor of trypsin-like protease and exhibits an inhibitory effect on IFN-γ activities.

Pt(II) Octaethylporphine ketone, a synthetic porphyrin compound, is frequently employed as a phosphorescent oxygen probe for assessing respiration in microbial systems.

Naginata ketone (Dehydroelsholtzione) is a natural furanone derived from a variety of plants and is used in biochemical experiments and organic synthesis.

Thiomichler's ketone (4,4'-Bis(dimethylamino)thiobenzophenone) is a photometric reagent suitable for detecting gold, palladium, platinum, mercury, silver, and copper. Additionally, it serves as a biomaterial or organic compound used in life sciences research.

Imidazole ketone erastin (IKE) is an ferroptosis inducer with inhibitory effects on system Xc-cystine/glutamate transporter proteins. Imidazole ketone erastin has antitumor activity and induces glutathione depletion and lipid peroxidation.

Cyclohexylphenylketone (AI311009) can be used as a photo-initiator and a spectrophotometric determination of benzophenone.

1. Raspberry ketone (p-Hydroxybenzyl acetone) is cytotoxic to melanocytes through the binding of RK-derived quinones to thiol proteins and the pro-oxidant activity of the RK-oligomer, the exposure of human skin to RK can cause chemical/occupational leukoderma. 2. Raspberry ketone is marketed on the Internet as a food supplement.

Cyclopropyl methyl ketone is a ketone compound widely used in biochemical experiments and drug synthesis research.

Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.

Raspberry ketone glucoside, a natural compound found in raspberry fruit, exhibits prolonged inhibition of melanogenesis and various melanogenic factors following its degradation in the skin.

Ezetimibe ketone (EZM-K) is a metabolite of Ezetimibe with antioxidant activity, alleviating H2O2-induced apoptosis and reactive oxygen species (ROS) in NRK-52E cells, upregulating Nrf2 and HO-1 levels.

Watermelon ketone (7-Methyl-2H-1,5-benzodioxepin-3(4H)-one) is a fragrance compound, with a special odorant. It has been widely used in the fragrance industry.

Dicyclohexyl ketone (Cyclohexane ketone) is a vulcanization accelerator.

Divinyl ketone is a kind of high reactivity, easy polymerization of multifunctional cyclization reagent.

Perilla ketone is a natural furan-type monoterpene compound found primarily in Perilla frutescens, a plant of the Lamiaceae family. Perilla ketone exhibits significant pulmonary toxicity; it can be activated by cytochrome P450 enzymes in the lungs, leading to severe lung injury and the development of diffuse pulmonary edema.

Cyclopentyl phenyl ketone (Benzoylcyclopentane) is used for the prevention and treatment of traumatic stress.

Grasshopper ketone, isolated from the brown alga Sargassum, is a potent inhibitor of LPS-induced NO production in RAW 264.7 cells and induces anti-inflammatory effects by inhibiting MAPK (ERK, JNK and p38) and NF-κB p65 phosphorylation.

BD-AcAc 2 (Ketone Ester) is a ketone monoester and can be used as a source of oral nutritional ketones. BD-AcAc 2 can elevate plasma levels of acetoacetate and β-hydroxybutyrate, blood Na+, blood glucose levels and blood creatinine levels after oral administration in mice. BD-AcAc 2 can partly prevent muscle weakness in septic mice. BD-AcAc 2 exhibits potential to improve endurance and exercise performance in animal body. BD-AcAc 2 can also be used to research diabetes or Parkinson's disease.

NNK is a nitrosated derivative of nicotine that activates the ERK1/2 and PKCα signaling pathways, induces Bcl2 phosphorylation at Ser70, and activates c-Myc at Thr58 and Ser62, thereby promoting the proliferation and survival of human lung cancer cells, and is commonly used to establish lung cancer mouse models.

AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid and a potent, selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2). By blocking the production of arachidonate and 12-hydroxyeicosatetraenoic acid in calcium ionophore-challenged platelets, AACOCF3 hinders their synthesis. Additionally, AACOCF3 inhibits glucose-induced insulin secretion from isolated rat islets, making it promising for cardiovascular disease research.

Deoxybenzoin (2-Phenylacetophenone) is used to target immune sensors and xanthine oxidase. It is used for the treatment of gout.

2-Acetonaphthone (beta-Naphthyl methyl ketone) is a fragrance, anticonvulsant, and antimicrobial agent. It has an onion type flavor and a sulfurous type odor.