Transforming growth factor beta (TGFβ) receptors are single pass serine/threonine kinase receptors that belong to TGF-β receptor family. They exist in several different isoforms that can be homo- or heterodimeric. TGF-β is a growth factor and cytokine involved in paracrine signalling and can be found in many different tissue types, including brain, heart, kidney, liver, bone, and testes. Over-expression of TGF-β can induce renal fibrosis, causing kidney disease, as well as diabetes, and ultimately end-stage renal disease.
Cat No. | product name / Synonyms | Species | Expression System |
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TMPJ-00304 | ALK-1 Protein, Mouse, Recombinant (hFc)
ALK-1 Protein, Mouse, Recombinant (hFc)
|
Mouse | Human Cells |
Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands, which mediates signaling of BMP9 (bone morphogenet... | |||
TMPJ-00314 | ACVR2B Protein, Human, Recombinant (hFc & His)
ACVR2B Protein, Human, Recombinant (hFc & His)
|
Human | Human Cells |
Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily, exert their biological actions by binding to heteromeric receptor comple... | |||
TMPJ-00315 | ACVR2A Protein, Human, Recombinant (hFc & His)
ACVR2A Protein, Human, Recombinant (hFc & His)
|
Human | Human Cells |
Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II rec... | |||
TMPJ-00325 | BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)
BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)
|
Human | Human Cells |
Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors... | |||
TMPJ-00333 | TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)
TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)
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Mouse | Human Cells |
Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β re... | |||
TMPJ-00334 | TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)
|
Mouse | Human Cells |
Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β re... | |||
TMPJ-01158 | ALK-2/ACVR1 Protein, Human, Recombinant (hFc)
ALK-2/ACVR1 Protein, Human, Recombinant (hFc)
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Human | Human Cells |
Activin RIA, also known as ALK-2, TSK-7L, SKR1, TSR-I, and ACTR-I, is a glycosylated 65 kDa type I receptor in the TGF-beta serine/threonine kinase receptor fami... | |||
TMPJ-01178 | TGFBR1 Protein, Mouse, Recombinant (hFc)
TGFBR1 Protein, Mouse, Recombinant (hFc)
|
Mouse | Human Cells |
TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine/threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms ... | |||
TMPK-00305 | TGFBR1 Protein, Human, Recombinant (mFc & Avi)
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
|
Human | HEK293 |
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpr... | |||
TMPK-00306 | TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated
TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated
|
Human | HEK293 |
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpr... | |||
TMPK-00328 | TGFBR2 Protein, Human, Recombinant (mFc & Avi)
TGFBR2 Protein, Human, Recombinant (mFc & Avi)
|
Human | HEK293 |
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from t... | |||
TMPK-00329 | TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated
TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated
|
Human | HEK293 |
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from t... | |||
TMPY-00310 | ALK-1 Protein, Cynomolgus, Recombinant (His)
ALK-1 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 |
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (tr... | |||
TMPY-00444 | ALK-4/ACVR1B Protein, Mouse, Recombinant (hFc)
ALK-4/ACVR1B Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and... | |||
TMPY-00486 | ALK-7 Protein, Human, Recombinant (hFc)
ALK-7 Protein, Human, Recombinant (hFc)
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Human | HEK293 |
ALK-7, also known as ALK7 and ACVR1C, belongs to the ALK family. It is a type I receptor for the TGFB family of signaling molecules. TGF-β is the prototype of a ... | |||
TMPY-00614 | BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)
BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)
|
Canine | HEK293 |
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins... | |||
TMPY-00650 | ALK-1 Protein, Human, Recombinant (hFc)
ALK-1 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (tr... | |||
TMPY-00658 | ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc)
ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc)
|
Human | HEK293 |
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK... | |||
TMPY-00659 | ACVR2A Protein, Human, Recombinant (hFc)
ACVR2A Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
ACVR2A and ACVR2B are two activin type II receptors. ACVR2A has been shown to interact with INHBA, SYNJ2BP and ACVR1B. The bovine ACVR2A gene encodes a protein o... | |||
TMPY-00662 | ALK-1 Protein, Mouse, Recombinant (His & hFc)
ALK-1 Protein, Mouse, Recombinant (His & hFc)
|
Mouse | HEK293 |
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (tr... |