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Fibroblast Growth Factor Receptors, FGFRs

The fibroblast growth factor receptors (FGFR) are receptors that bind to members of the fibroblast growth factor (FGF) family of proteins. The fibroblast growth factor receptors consist of an extracellular ligand domain composed of three immunoglobulin-like domains, a single transmembrane helix domain, and an intracellular domain with tyrosine kinase activity. The FGF/FGFR signalling pathway is involved in a variety of cancers.There are non-selective FGFR inhibitors that act on all of FGFR1-4 and other proteins, and some selective FGFR inhibitors for some/all of FGFR1-4. Selective FGFR inhibitors include AZD4547, BGJ398, JNJ42756493, and PD173074.

FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00395
Expression system: HEK293 Cells
Length: 22-374, Partial
Activity: ELISA
  • $91
7-10 days
Size
QTY
SPR-compatible buffer
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
TMPY-06036
Expression system: HEK293 Cells
Length: 1-310 and 359-374 linked by FGFR1 IIIb Ig domain, Partial
Activity: Not Tested
  • $47
7-10 days
Size
QTY
SPR-compatible buffer
FGFR1 Protein, Human, Recombinant (beta (IIIb), His)
TMPY-06034
Expression system: HEK293 Cells
Length: 1-221 and 270-285 linked by the FGFR1 IIIb Ig domain, Partial
Activity: Not Tested
  • $44
7-10 days
Size
QTY
SPR-compatible buffer
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
TMPK-00398
Expression system: HEK293 Cells
Length: 253-378, Partial
Activity: ELISA
  • $63
7-10 days
Size
QTY
SPR-compatible buffer
FGFR4 Protein, Human, Recombinant (His)
TMPY-02112
Expression system: HEK293 Cells
Length: 1-369, Partial
Activity: Cells Activity
  • $52
7-10 days
Size
QTY
SPR-compatible buffer
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)
TMPY-00423
Expression system: HEK293 Cells
Length: 1-378, Partial
Activity: ELISA、Cells Activity
  • $44
7-10 days
Size
QTY
SPR-compatible buffer
FGFR2 Protein, Human, Recombinant (His & hFc)
TMPY-00972
Expression system: HEK293 Cells
Length: 1-377, Partial
Activity: Cells Activity
  • $48
7-10 days
Size
QTY
SPR-compatible buffer
FGFR2 Protein, Mouse, Recombinant (hFc)
TMPY-03357
Expression system: HEK293 Cells
Length: 1-263, Partial
Activity: Cell Activity
  • $48
7-10 days
Size
QTY
SPR-compatible buffer
FGFR3 Protein, Human, Recombinant (His)
TMPY-04165
Expression system: HEK293 Cells
Length: 1-375, Extracellular Domain
Activity: Not Tested
  • $47
7-10 days
Size
QTY
SPR-compatible buffer
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
TMPY-00341
Expression system: HEK293 Cells
Length: 1-377, Partial
Activity: Not Tested
  • $44
7-10 days
Size
QTY
SPR-compatible buffer
FGFR1 Protein, Human, Recombinant (His)
TMPY-01011
Expression system: HEK293 Cells
Length: 1-285, Extracellular Domain
Activity: BLI, Cell Activity
  • $48
7-10 days
Size
QTY
SPR-compatible buffer
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
TMPJ-00391
Expression system: HEK293 Cells
Length: 22-378, Partial
Activity: Not Tested
  • $55
7-10 days
Size
QTY
SPR-compatible buffer
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
TMPK-00847
Expression system: HEK293 Cells
Length: 39-263, Partial
Activity: Not Tested
  • $58
7-10 days
Size
QTY
SPR-compatible buffer
FGFR4 Protein, Human, Recombinant (His & Avi)
TMPK-00379
Expression system: HEK293 Cells
Length: 22-369, Partial
Activity: Not Tested
  • $32
7-10 days
Size
QTY
SPR-compatible buffer
FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00381
Expression system: HEK293 Cells
Length: 22-369, Partial
Activity: Not Tested
  • $91
7-10 days
Size
QTY
SPR-compatible buffer
FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00401
Expression system: HEK293 Cells
Length: 22-378, Partial
Activity: ELISA
  • $91
7-10 days
Size
QTY
SPR-compatible buffer
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00391
Expression system: HEK293 Cells
Length: 127-377, Partial
Activity: ELISA
  • $91
7-10 days
Size
QTY
SPR-compatible buffer
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
TMPK-00392
Expression system: HEK293 Cells
Length: 158-355, Partial
Activity: ELISA
  • $44
7-10 days
Size
QTY
SPR-compatible buffer
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00380
Expression system: HEK293 Cells
Length: 152-369, Partial
Activity: Not Tested
  • $91
7-10 days
Size
QTY
SPR-compatible buffer
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
TMPK-00384
Expression system: HEK293 Cells
Length: 23-375, Extracellular Domain
Activity: ELISA
  • $44
7-10 days
Size
QTY
SPR-compatible buffer
FGFR4 Protein, Human, Recombinant (hFc)
TMPY-00806
Expression system: HEK293 Cells
Length: 1-369, Partial
Activity: Cells Activity
  • $68
7-10 days
Size
QTY
SPR-compatible buffer
FGFR4 Protein, Mouse, Recombinant (His & hFc)
TMPY-01019
Expression system: HEK293 Cells
Length: 1-366, Partial
Activity: Cells Activity
  • $68
7-10 days
Size
QTY
SPR-compatible buffer
FGFR2 Protein, Mouse, Recombinant (His)
TMPY-03389
Expression system: HEK293 Cells
Length: 1-263, Partial
Activity: Not Tested
  • $68
7-10 days
Size
QTY
SPR-compatible buffer
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)
TMPK-00686
Expression system: HEK293 Cells
Length: 22-349, Partial
Activity: Not Tested
  • $51
7-10 days
Size
QTY
SPR-compatible buffer