Bone Morphogenetic Proteins, BMPs

Expression system: E. coli
Length: 293-408 (mutation), Full Length of Mature Protein
Activity: Cell Activity

BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.5 kDa and the accession number is C8C060.

BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13 kDa and the accession number is P12643.

Expression system: E. coli
Length: 283-396, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 382-513, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 293-408, Full Length of Mature Protein
Activity: Not Tested

Bone Morphogenetic Protein 5 (BMP-5) is a member of the structurally and functionally related bone morphogenetic proteins (BMPs) which constitute a novel subfamily of the transforming growth factor β (TGF-β) superfamily. In agreement with a possible role in the control of cell death, BMP-5 exhibited a regulated pattern of expression in the interdigital tissue. Transcripts of BMP-5 and BMP-5 protein were abundant within the cytoplasm of the fragmenting apoptotic interdigital cells in a way suggesting that delivery of BMPs into the tissue is potentiated during apoptosis. Gain-of-function experiments demonstrated that BMP-5 has the same effect as other interdigital BMPs inducing apoptosis in the undifferentiated mesoderm and growth in the prechondrogenic mesenchyme. BMP-5 is a member of the 60A subgroup of BMPs, other members of which have been shown to stimulate dendritic growth in central and peripheral neurons. The signaling pathway that mediates the dendrite-promoting activity of BMP-5 may involve binding to BMPR-IA and activation of Smad-1, and relative levels of BMP antagonists such as noggin and follistatin may modulate BMP-5 signaling. Since BMP-5 is expressed at relatively high levels not only in the developing but also the adult nervous system, these findings suggest the possibility that BMP-5 regulates dendritic morphology not only in the developing but also the adult nervous system. BMP-5 may play important roles not only in myocardial differentiation but also in the formation and maintenance of endocardial cushion tissue. Additionally, a high expression level of BMP-5 has been detected in certain tumors of mesenchymal origin.

Expression system: HEK293 Cells
Length: 32-143, Partial
Activity: Not Tested

Expression system: E. coli
Length: 293-408, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 32-143, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 293-431, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 299-407, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli Length: 283-396, Full Length of Mature Protein Activity: Cell Activity

Expression system: E. coli
Length: 294-409, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 359-468, Full Length of Mature Protein
Activity: Not Tested

BMP-2 Protein, Danio rerio (zebrafish), Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.2 kDa and the accession number is B3DI86.

BMP-15 Protein, Sheep, Recombinant (His & Myc) is expressed in E. coli. The accession number is Q9MZE2.

Expression system: E. coli
Length: 268-392, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 293-431, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 293-431, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 32-143, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 316-431, Partial
Activity: Cell Activity

Expression system: E. coli
Length: 363-472, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 367-476, Partial
Activity: Not Tested