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Growth Factors

Angiopoietin

(64)

Bone Morphogenetic Proteins, BMPs

(22)

Ephrin Family

(53)

Epidermal Growth Factor Family, EGFs

(58)

Fibroblast Growth Factors, FGFs

(67)

Insulin-like Growth Factors, IGFs

(59)

Neurotrophins

(115)

Platelet-Derived Growth Factors, PDGFs

(27)

Transforming Growth Factor-β family, TGF-βs

(96)

Vascular Endothelial Growth Factors, VEGFs

(46)

Platelet-Derived Growth Factors, PDGFs

Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays an important role in blood vessel formation, blood vessel growth in existing vascular tissues, mitosis of mesenchymal cells, and chemotaxis of mesenchymal cells. Platelet-derived growth factor is a dimeric glycoprotein that can be composed of two A subunits (PDGF-AA), two B subunits (PDGF-BB), or one of each (PDGF-AB). There are five different isoforms of PDGF that activate cellular response through two different receptors. Known ligands include: PDGF-AA (PDGFA), -BB (PDGFB), -CC (PDGFC), and -DD (PDGFD), and -AB (a PDGFA and PDGFB heterodimer). The ligands interact with the two tyrosine kinase receptor monomers, PDGFRα (PDGFRA) and -Rβ (PDGFRB). Recombinant PDGF is used in medicine to help heal chronic ulcers and in orthopedic surgery and periodontics as an alternative to bone autograft to stimulate bone regeneration and repair.

Filter HomeRecombinant ProteinsCytokines and Growth FactorsGrowth FactorsPlatelet-Derived Growth Factors, PDGFs

PDGF-BB Protein, Human, Recombinant

TMPJ-00735

Expression system: E. coli
Length: 82-190, Full Length of Mature Protein
Activity: Cell Activity

$118

In Stock

Size

QTY

PDGF-BB Protein, Mouse, Recombinant (His)

TMPJ-00562

Expression system: E. coli
Length: 82-190, Full Length of Mature Protein
Activity: Not Tested

In Stock

Size

QTY

PDGFB Protein, Human, Recombinant (His)

TMPY-04644

Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.3 kDa and the accession number is P01127-2.

$386

In Stock

Size

QTY

PDGF-BB Protein, Mouse, Recombinant

TMPS-00116

PDGF-BB Protein, Mouse, Recombinant is expressed in E. coli. The accession number is P31240.

$170

7-10 days

Size

QTY

PDGF-AA Protein, Human, Recombinant

TMPJ-00767

PDGF-AA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 KDa and the accession number is P04085.

$184

7-10 days

Size

QTY

PDGFC Protein, Cynomolgus, Recombinant (hFc)

TMPY-00269

PDGFC Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.9 kDa and the accession number is G7P6G9.

$618

7-10 days

Size

QTY

PDGFB Protein, Cynomolgus, Recombinant (mFc)

TMPY-02395

Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 38.9 kDa and the accession number is G7PFK7.

$695

7-10 days

Size

QTY

PDGFA Protein, Human, Recombinant (His)

TMPY-05056

Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. PDGFA Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 16.3 kDa and the accession number is AAA60045.1.

$462

7-10 days

Size

QTY

PDGFB Protein, Rhesus, Recombinant (His)

TMPY-05077

Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Rhesus, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.2 kDa and the accession number is A0A1D5Q4I7.

$539

7-10 days

Size

QTY

PDGF-CC Protein, Human, Recombinant

TMPS-00118

PDGF-CC Protein, Human, Recombinant is expressed in HEK293 Cells. The accession number is Q9NRA1.

$138

7-10 days

Size

QTY

PDGFA Protein, Mouse, Recombinant (His)

TMPY-04838

Expression system: P. pastoris (Yeast)
Length: 87-196, Partial
Activity: Not Tested

$600

7-10 days

Size

QTY

PDGFC Protein, Mouse, Recombinant (His)

TMPY-04976

Expression system: P. pastoris (Yeast)
Length: 235-345, Partial
Activity: Not Tested

$397

In Stock

Size

QTY

PDGFA Protein, Rat, Recombinant (His)

TMPY-05068

Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. PDGFA Protein, Rat, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.5 kDa and the accession number is AAB26134.2.

$498

7-10 days

Size

QTY

PDGFA Protein, Canine, Recombinant (His)

TMPY-05075

Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. PDGFA Protein, Canine, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.5 kDa and the accession number is A0A8C0M6T8.

$462

7-10 days

Size

QTY

PDGF-AA Protein, Mouse, Recombinant

TMPS-00114

PDGF-AA Protein, Mouse, Recombinant is expressed in E. coli. The accession number is P20033.

$198

7-10 days

Size

QTY

PDGFD Protein, Cynomolgus, Recombinant (His)

TMPK-01178

Expression system: HEK293 Cells
Length: 19-370, Full Length of Mature Protein
Activity: Not Tested

$487

7-10 days

Size

QTY

PDGFD Protein, Mouse, Recombinant (His & SUMO)

TMPH-02835

Expression system: E. coli
Length: 24-370, Full Length of Mature Protein
Activity: Not Tested

$284

20 days

Size

QTY

PDGFB Protein, Canine, Recombinant (His)

TMPY-05076

Expression system: P. pastoris (Yeast)
Length: 82-190, Partial
Activity: Not Tested

$539

7-10 days

Size

QTY

PDGFA Protein, Canine, Recombinant (hFc)

TMPY-00455

Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. PDGFA Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is A0A8C0M6T8.

$243

7-10 days

Size

QTY

PDGF-BB Protein, Bovine, Recombinant

TMPS-00115

PDGF-BB Protein, Bovine, Recombinant is expressed in P. pastoris (Yeast). The accession number is B1H0W5.

$247

7-10 days

Size

QTY

PDGF-DD Protein, Human, Recombinant

TMPS-00119

PDGF-DD Protein, Human, Recombinant is expressed in CHO Cells. The accession number is Q9GZP0.

$170

7-10 days

Size

QTY

PDGF-AA Protein, Human, Recombinant (His)

TMPJ-00768

PDGF-AA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16 KDa and the accession number is P04085.