Angiopoietin

Expression system: CHO Cells
Length: 1-496, Full Length
Activity: ELISA

Expression system: HEK293 Cells
Length: 1-261 and 277-498 linked by a polypeptide linker, Partial
Activity: Not Tested

ANGPT2 Angiopoietin-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.5 kDa and the accession number is B9EHQ4.

Expression system: HEK293 Cells
Length: 1-496, Full Length
Activity: ELISA

TIE2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82 kDa and the accession number is AAA61139.1.

TIE2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 108.5 kDa and the accession number is AAA61139.1.

Expression system: HEK293 Cells
Length: 166-406, Partial
Activity: Not Tested

ANGPT2 Angiopoietin-2 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.7 kDa and the accession number is XP_005562586.1&XP_001097949.1.

Expression system: HEK293 Cells
Length: 245-493, Partial
Activity: Not Tested

TIE2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 107.7 kDa and the accession number is B1AWS8.

ANGPT1 Angiopoietin-1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28 kDa and the accession number is O08538.

ANGPT2 Angiopoietin-2 Protein, Cynomolgus, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.8 kDa and the accession number is XP_005562586.1&XP_001097949.1.

TIE2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.2 kDa and the accession number is G7NFP9.

Expression system: HEK293 Cells
Length: 282-503, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 17-219, Partial
Activity: ELISA、SPR

Expression system: HEK293 Cells
Length: 20-497, Full Length of Mature Protein
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 770-1122, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 23-745, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 27-346, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-744, Partial
Activity: ELISA

ANGPT2 Angiopoietin-2 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.8 kDa and the accession number is A0A8J8.

TIE2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 108 kDa and the accession number is A6JRG8.

Angiopoietin-like protein 1 (ANGPTL1) has been reported to suppress migration and invasion in lung and breast cancer, acting as a novel tumor suppressor candidate. Downregulation of tumor suppressor signaling plays an important role in the pathogenesis of hepatocellular carcinoma (HCC).The downregulation of the angiopoietin-like protein ANGPTL1 is associated with vascular invasion, tumor thrombus, metastasis, and poor prognosis in HCC. Ectopic expression of ANGPTL1 in HCC cells effectively decreased their in vitro and in vivotumorigenicity, cell motility, and angiogenesis. shRNA-mediated depletion of ANGPTL1 exerted opposing effects. ANGPTL1 promoted apoptosis via inhibition of the STAT3 Bcl-2-mediated antiapoptotic pathway and decreased cell migration and invasion via downregulation of transcription factors SNAIL and SLUG. Furthermore, ANGPTL1 inhibited angiogenesis by attenuating ERK and AKT signaling and interacted with integrin α1β1 receptor to suppress the downstream FAK Src-JAK-STAT3 signaling pathway. Taken together, these results suggest ANGPTL1 as a prognostic biomarker and novel therapeutic agent in HCC. ANGPTL1 expression was down-regulated in CRC tissues and inversely correlated with poor survival. ANGPTL1 repressed migration and invasion of CRC cells, and microRNA-138 was involved in this process. Angiopoietin-like protein 1 (ANGPTL1) has been shown to act as a tumor suppressor by inhibiting angiogenesis, cancer invasion, and metastasis.

Angiopoietin-like 7 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63.8 kDa and the accession number is E2R2G1.