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Breast Cancer Modeling

Breast cancer is one of the most common malignancies in women and is characterized by significant heterogeneity. Based on hormone receptor status and HER2 expression, it can be classified into multiple subtypes. Breast tumor models are widely used to study the estrogen signaling pathway, HER2-targeted therapies, and the evaluation of novel anticancer treatments.

N-Nitroso-N-methylurea
T4169684-93-5
N-Nitroso-N-methylurea (NMU/MNU/NMH) is a nitrosourea compound with alkylating, carcinogenic, and mutagenic properties; as a direct-acting alkylating agent, it interacts with DNA and targets multiple animal organs to induce various cancers and degenerative diseases, and is commonly used to induce disease models such as gastric cancer and breast cancer in mice.
  • $36
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DMBA
T3669657-97-6
DMBA (7,12-Dimethylbenz[a]anthracene) is a carcinogenic polycyclic aromatic hydrocarbon (PAH) that can be used to induce animal models of leukemia, liver cancer, breast cancer, skin cancer, and lung cancer. It is also capable of inducing programmed cell death (apoptosis) in A20.1 murine B-cell lymphoma.
  • $30
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Nitrofurazone
T089759-87-0
Nitrofurazone (Nitrofural; Furacilin) is an orally active nitroaromatic broad-spectrum antibiotic with activity against both Gram-positive and Gram-negative bacteria. It is commonly used for establishing breast cancer models.
  • $30
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