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Other Tumor Modeling

In addition to common solid tumors, glioma, pancreatic cancer, prostate cancer, and ovarian cancer also hold significant clinical relevance. Tumor modeling techniques include chemical carcinogenesis, transgenic engineering, patient-derived xenografts (PDX), organoid structures, and 3D organoid models. These diverse approaches provide robust support for precision therapy and mechanistic studies across various tumor types.

N,N'-Dinitrosopiperazine
DNPZ, 1,4-Dinitrosopiperazine
T81720140-79-4
N,N'-Dinitrosopiperazine (1,4-Dinitrosopiperazine, DNP) is a known carcinogen associated with the development and metastasis of nasopharyngeal carcinoma. Its carcinogenic mechanism involves multiple signaling pathways, particularly exerting effects through the regulation of phosphorylation at the Ser568 site of the LYRIC protein. It can be used to induce esophageal cancer models.
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8-10 weeks
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