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Kidney Cancer Modeling

Renal cell carcinoma (RCC) is the most common type of malignant kidney tumor in adults and is closely associated with VHL gene mutations and dysregulation of the HIF signaling pathway. Modeling strategies include xenograft transplantation, genetically engineered mouse models, and CRISPR-based gene editing. These models are widely used to investigate the roles of metabolic dysregulation, angiogenesis, and immunotherapy in RCC.

Ferric nitrilotriacetate
T7865516448-54-7
Ferric nitrilotriacetate (Fe-NTA) is a highly active compound formed by the complexation of iron and nitrilotriacetic acid. It is primarily used to induce degenerative diseases through oxidative stress (OS) and can be applied to establish disease models such as acute kidney injury, renal cell carcinoma, liver cancer, and diabetes.
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8-10 weeks
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