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Liver cancer is one of the most prevalent and deadly malignancies worldwide, primarily including hepatocellular carcinoma (HCC) and cholangiocarcinoma. Its development is closely associated with chronic viral hepatitis, liver cirrhosis, and metabolic disorders. In animal model construction, liver cancer is commonly simulated through chemical induction, genetic engineering, or xenograft transplantation, providing critical support for drug screening and the investigation of targeted therapeutic mechanisms.
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