T4620 |
Siramesine
|
147817-50-3
|
98%
|
|
Siramesine(Lu 28-179) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of cancer cells and to exhibit a potent anticancer acti...
|
T1865 |
S1RA
|
878141-96-9
|
98%
|
|
S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM) antagonist, showed good selectivity against σ2R (Ki > 1000 nM).
|
T19341 |
Glycerol phenylbutyrate-D15
|
T19341
|
98%
|
|
Glycerol phenylbutyrate-D15 is a deuterium-labeled Glycerol phenylbutyrate. Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand (pKi: 8.02).
|
T16445 |
PD 144418
|
154130-99-1
|
98%
|
|
PD 144418 displays potential antipsychotic activity. PD 144418 is a high affinity, potent and selective sigma 1 (σ1) receptor ligand (Ki: 0.08 nM and 1377 nM for...
|
T19342 |
Glycerol phenylbutyrate-D5
|
T19342
|
98%
|
|
Glycerol phenylbutyrate-D5 is a deuterium-labeled Glycerol phenylbutyrate. Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand (pKi: 8.02).
|
T12912 |
Sigma-1 receptor antagonist 3
|
1639220-17-9
|
98%
|
|
Sigma-1 receptor antagonist 3 is a potent and selective antagonist of Sigma-1 (σ1) receptor(Ki : 1.14 nM), has the potential for the neuropathic pain.
|
T12911 |
Sigma-1 receptor antagonist 2
|
1639220-15-7
|
98%
|
|
Sigma-1 receptor antagonist 2 is a potent and selective antagonist of sigma 1 receptor (σ1 R) (σ1 and σ2 receptor with Kis of 3.88 and 1288 nM , respectively).
|
T22904 |
L-745870 trihydrochloride
|
866021-03-6
|
98%
|
|
highly potent and selective D4 dopamine receptor antagonist
|
T21788 |
BD 1008 dihydrobromide
|
138356-09-9
|
|
|
BD1008 dihydrobromide is a selective antagonist of the sigma 1 (σ1) receptor (Ki = 2 nM). BD1008 dihydrobromide have high affinity for sigma1 receptors, moderate...
|
T1180 |
Blonanserin
|
132810-10-7
|
100%
|
|
Blonanserin is an atypical antipsychotic approved in Japan in January, 2008. Relative to many other antipsychotics, blonanserin has an improved tolerability prof...
|
T15034 |
Roluperidone
|
359625-79-9
|
97.77%
|
|
Roluperidone is a novel cyclic amide derivative. It has high equipotent affinities for 5-HT2A and σ2 receptors (Ki of 7.53 nM and 8.19 nM for 5-HT2A and σ2).
|
T5969 |
Ditolylguanidine
|
97-39-2
|
98%
|
|
Ditolylguanidine is an agonist of sigma receptor (σ1/σ2 receptor).
|
T20797 |
NE-100 hydrochloride
|
149409-57-4
|
98.85%
|
|
NE100 HCl is a potent and selective antagonist of sigma-1 receptor.
|
T3597 |
Cutamesine dihydrochloride
|
165377-44-6
|
99%
|
|
Cutamesine dihydrochloride is a selective σ1 receptor agonist (IC50: 17.4 nM). It shows selectivity for σ1 over σ2 receptors, and inhibits angiotensin II-induced...
|
T4596 |
4-IBP
|
155798-08-6
|
99.12%
|
|
4-IBP is a selective σ1 agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM) .
|
T8834 |
EST64454 hydrochloride
|
1950569-11-5
|
99.15%
|
|
EST64454 is a highly soluble σ1 receptor antagonist (Ki : 22 nM),has the potential for Pain Management.
|
T7488 |
BD1063 dhydrochloride
|
206996-13-6
|
99.33%
|
|
BD1063 is a potent and selective sigma 1(σ1) receptor antagonist(Ki = 9 nM).
|
T1740 |
BD-1047 dihydrobromide
|
138356-21-5
|
99.39%
|
|
BD-1047 hydrobromide, a selective functional antagonist of sigma receptors, has antipsychotic activity in animal models predictive of efficacy in schizophrenia.
|
T7952 |
Noscapine
|
128-62-1
|
99.43%
|
|
Noscapine is a Non-addictive Opioid and Microtubule-Inhibitor in Potential Treatment of Glioblastoma.
|
T3198L |
PRE-084 hydrochloride
|
75136-54-8
|
99.61%
|
|
PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).
|