T16445 |
PD 144418
|
154130-99-1
|
98%
|
|
PD 144418 displays potential antipsychotic activity. PD 144418 is a high affinity, potent and selective sigma 1 (σ1) receptor ligand (Ki: 0.08 nM and 1377 nM for...
|
T19341 |
Glycerol phenylbutyrate-D15
|
T19341
|
98%
|
|
Glycerol phenylbutyrate-D15 is a deuterium-labeled Glycerol phenylbutyrate. Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand (pKi: 8.02).
|
T4620 |
Siramesine
|
147817-50-3
|
98%
|
|
Siramesine(Lu 28-179) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of cancer cells and to exhibit a potent anticancer acti...
|
T19342 |
Glycerol phenylbutyrate-D5
|
T19342
|
98%
|
|
Glycerol phenylbutyrate-D5 is a deuterium-labeled Glycerol phenylbutyrate. Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand (pKi: 8.02).
|
T1865 |
S1RA
|
878141-96-9
|
98%
|
|
S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM) antagonist, showed good selectivity against σ2R (Ki > 1000 nM).
|
T22904 |
L-745870 trihydrochloride
|
866021-03-6
|
98%
|
|
highly potent and selective D4 dopamine receptor antagonist
|
T77340L |
AB21 HCl
|
|
98%
|
|
AB21 HCl is a selective antagonist of the σ1 receptor, with Kis of 13 nM for σ1 receptor and 102 nM for σ2 receptor. AB21 HCl is known for its ability to reduce ...
|
T13510 |
Sigma-LIGAND-1
|
139652-01-0
|
98%
|
|
Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 has a Ki of 4000...
|
T12912 |
Sigma-1 receptor antagonist 3
|
1639220-17-9
|
98%
|
|
Sigma-1 receptor antagonist 3 is a potent and selective antagonist of Sigma-1 (σ1) receptor(Ki : 1.14 nM), has the potential for the neuropathic pain.
|
T1180 |
Blonanserin
|
132810-10-7
|
98%
|
|
Blonanserin is an atypical antipsychotic approved in Japan in January, 2008. Relative to many other antipsychotics, blonanserin has an improved tolerability prof...
|
T15034 |
Roluperidone
|
359625-79-9
|
98%
|
|
Roluperidone is a novel cyclic amide derivative. It has high equipotent affinities for 5-HT2A and σ2 receptors (Ki of 7.53 nM and 8.19 nM for 5-HT2A and σ2).
|
T21788 |
BD 1008 dihydrobromide
|
138356-09-9
|
98%
|
|
BD 1008 dihydrobromide is a selective antagonist of the sigma 1 (σ1) receptor (Ki = 2 nM). BD 1008 dihydrobromide have high affinity for sigma1 receptors, modera...
|
T5969 |
Ditolylguanidine
|
97-39-2
|
98%
|
|
Ditolylguanidine is an agonist of sigma receptor (σ1/σ2 receptor).
|
T22612 |
BMY-14802 hydrochloride
|
105565-55-7
|
98%
|
|
BMY-14802 hydrochloride is a selective antagonist of σ receptor (IC50 = 112 nM) with antipsychotic effects. BMY-14802 hydrochloride is an agonist of the α1-adren...
|
T20797 |
NE-100 hydrochloride
|
149409-57-4
|
98%
|
|
NE100 HCl is a potent and selective antagonist of sigma-1 receptor.
|
T67739 |
BMY-14802
|
105565-56-8
|
98%
|
|
BMY-14802 is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.
|
T3597 |
Cutamesine dihydrochloride
|
165377-44-6
|
98%
|
|
Cutamesine dihydrochloride is a selective σ1 receptor agonist (IC50: 17.4 nM). It shows selectivity for σ1 over σ2 receptors, and inhibits angiotensin II-induced...
|
T72059 |
S1R agonist 2
|
150085-21-5
|
98%
|
|
S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.
|
T39211 |
PD 144418 oxalate
|
1794760-28-3
|
98%
|
|
PD 144418 oxalate is a highly potent and selective sigma 1 (σ1) receptor ligand, displaying a Ki value of 0.08 nM for σ1 and 1377 nM for σ2. It exhibits negligib...
|
T4596 |
4-IBP
|
155798-08-6
|
98%
|
|
4-IBP is a selective σ1 agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM) .
|