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Carbonic Anhydrase

The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions). The active site of most carbonic anhydrases contains a zinc ion. They are therefore classified as metalloenzymes. The enzyme maintains acid-base balance and helps transport carbon dioxide.
Cat. No. Product name CAS No. Purity Chemical Structure
T0677 Chlorothiazide 58-94-6 95.42%
Chlorothiazide is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.
T0515 Tioxolone 4991-65-5 95.9%
Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.
T0738 Urea 57-13-6 98%
Urea is formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end metabolite of protein catabolism and accounts for ab...
T4S2354 Dimethylfraxetin 6035-49-0 98%
Dimethylfraxetin is a Carbonic anhydrase inhibitor(Ki:0.0097 μM)
T6781 Benzenesulfonamide 98-10-2 98%
Benzenesulfonamide ia an inhibitor of carbonic anhydrases.
T0675 Topiramate 97240-79-4 98%
Topiramate is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepat...
T36758 CAIX Inhibitor S4 1330061-67-0 98.35%
CAIX Inhibitor S4 is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively. The Kis for CA II and CA I are 546 and 5600 nM...
T21294 Polmacoxib 301692-76-2 98.49%
Polmacoxib is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant col...
T2S0357 6-Hydroxycoumarin 6093-68-1 98.5%
6-Hydroxycoumarin exhibits cytotoxicity against human HL60, HCT116, COLO205 cells with activity value of 35 uM, 42 uM, 37 respectively. 6-Hydroxycoumarin is a hu...
T6469 Dichlorphenamide 120-97-8 98.51%
Dichlorphenamide is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
T0114 Trichlormethiazide 133-67-5 99.32%
Trichlormethiazide is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appear...
T9323 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide 654-62-6 99.34%
4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide is a carbonic anhydrase inhibitor, used as a potential anti-tumor and antiglaucoma drug.
T2134 Dorzolamide hydrochloride 130693-82-2 99.48%
Dorzolamide Hydrochloride is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid co...
T0142 Brinzolamide 138890-62-7 99.5%
Brinzolamide is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.
T1026 Mafenide hydrochloride 138-37-4 99.53%
Mafenide hydrochloride is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.
T2017 U-104 178606-66-1 99.6%
U-104 is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM).
T0813 Acetazolamide 59-66-5 99.61%
Acetazolamide is a Carbonic Anhydrase Inhibitor. The mechanism of action of acetazolamide is as a Carbonic Anhydrase Inhibitor. The chemical classification of ac...
T5012 Ethoxzolamide 452-35-7 99.62%
Ethoxzolamide is a carbonic anhydrase inhibitor.
T1999 Taselisib 1282512-48-4 99.62%
Taselisib is an orally bioavailable inhibitor of the class I phosphatidylinositol 3-kinase (PI3K) alpha isoform (PIK3CA), with potential antineoplastic activity....
T1409 Methocarbamol 532-03-6 99.75%
Methocarbamol is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of muscu...
Chlorothiazide
T0677
Chlorothiazide is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.
Tioxolone
T0515
Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.
Urea
T0738
Urea is formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end metabolite of protein catabolism and accounts for ab...
Dimethylfraxetin
T4S2354
Dimethylfraxetin is a Carbonic anhydrase inhibitor(Ki:0.0097 μM)
Benzenesulfonamide
T6781
Benzenesulfonamide ia an inhibitor of carbonic anhydrases.
Topiramate
T0675
Topiramate is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepat...
CAIX Inhibitor S4
T36758
CAIX Inhibitor S4 is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively. The Kis for CA II and CA I are 546 and 5600 nM...
Polmacoxib
T21294
Polmacoxib is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant col...
6-Hydroxycoumarin
T2S0357
6-Hydroxycoumarin exhibits cytotoxicity against human HL60, HCT116, COLO205 cells with activity value of 35 uM, 42 uM, 37 respectively. 6-Hydroxycoumarin is a hu...
Dichlorphenamide
T6469
Dichlorphenamide is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
Trichlormethiazide
T0114
Trichlormethiazide is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appear...
4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
T9323
4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide is a carbonic anhydrase inhibitor, used as a potential anti-tumor and antiglaucoma drug.
Dorzolamide hydrochloride
T2134
Dorzolamide Hydrochloride is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid co...
Brinzolamide
T0142
Brinzolamide is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.
Mafenide hydrochloride
T1026
Mafenide hydrochloride is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.
U-104
T2017
U-104 is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM).
Acetazolamide
T0813
Acetazolamide is a Carbonic Anhydrase Inhibitor. The mechanism of action of acetazolamide is as a Carbonic Anhydrase Inhibitor. The chemical classification of ac...
Ethoxzolamide
T5012
Ethoxzolamide is a carbonic anhydrase inhibitor.
Taselisib
T1999
Taselisib is an orally bioavailable inhibitor of the class I phosphatidylinositol 3-kinase (PI3K) alpha isoform (PIK3CA), with potential antineoplastic activity....
Methocarbamol
T1409
Methocarbamol is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of muscu...
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