Carbonic Anhydrase

The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions). The active site of most carbonic anhydrases contains a zinc ion. They are therefore classified as metalloenzymes. The enzyme maintains acid-base balance and helps transport carbon dioxide.

Cat. No.	Product name	CAS No.	Purity
T34093	PNNP	330-13-2	98%
T34093	pNNP can be used as a substrate for the PP2C assay. pNNP inhibits β-carbonic anhydrase and α-carbonate dehydrogenase, as well as H. pylori Helicobacter pylori. p...
T38808	Cyclamic acid sodium	139-05-9	98%
T38808	Cyclamic acid sodium is a carbonic anhydrase inhibitor and one of the most widely used artificial sweeteners in food and pharmaceuticals.Cyclamic acid sodium sho...
T77560	2-Amino-4-(4-chlorophenyl)thiazole	2103-99-3	98%
T77560	2-AMINO-4-(4-CHLOROPHENYL)THIAZOLE is a 2-aminothiazole derivative. 2-AMINO-4-(4-CHLOROPHENYL)THIAZOLE inhibited hCA I, hCA II, AChE and BChE with Ki values of 0...
T68136	5-Hexenoic acid, 6-[4-[2-[[(4-chlorophenyl)sulfonyl]amino]ethyl]phenyl]-6-(3-pyridinyl)-	133276-52-5	98%
T68136	5-Hexenoic acid, 6-[4-[2-[[(4-chlorophenyl)sulfonyl]amino]ethyl]phenyl]-6-(3-pyridinyl)- shows activity against Carbonic anhydrase and Cyclooxygenase 2.
T67775	Enpp/Carbonic anhydrase-IN-1	2883495-35-8	98%
T67775	Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent inhibitor of Enpp and carbonic anhydrase. Enpp/Carbonic anhydrase-IN-1 exhibits IC50s of 1.36, 1.35, 3.00,...
T6581	Methyclothiazide	135-07-9	98%
T6581	Methyclothiazide is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including heart disease.
T0515	Tioxolone	4991-65-5	98%
T0515	Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.
T23782	Benzolamide	3368-13-6	98%
T23782	Benzolamide is an inhibitor of carbonic anhydrase. Benzolamide inhibits low-threshold calcium currents in hippocampal pyramidal neurons.
T61745	HCAI/II-IN-6	694466-00-7	98%
T61745	hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA). hCAI/II-IN-6 inhibited hCA I, hCA II, hCA VII, and hCA XII with Ki valu...
T0738	Urea	57-13-6	98%
T0738	Urea is formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end metabolite of protein catabolism and accounts for ab...
T0675	Topiramate	97240-79-4	98%
T0675	Topiramate is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepat...
T36758	CAIX Inhibitor S4	1330061-67-0	98%
T36758	CAIX Inhibitor S4 is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively. The Kis for CA II and CA I are 546 and 5600 nM...
T21294	Polmacoxib	301692-76-2	98%
T21294	Polmacoxib is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant col...
T2S0357	6-Hydroxycoumarin	6093-68-1	98%
T2S0357	6-Hydroxycoumarin exhibits cytotoxicity against human HL60, HCT116, COLO205 cells with activity value of 35 uM, 42 uM, 37 respectively. 6-Hydroxycoumarin is a hu...
T6469	Dichlorphenamide	120-97-8	98%
T6469	Dichlorphenamide is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
T73177	HCAII-IN-9	2878477-18-8	98%
T73177	hCAII-IN-9 is a potent carbonic anhydrase inhibitor that inhibits hCA II, hCA IX, and hCA XII with IC50s of 1.18 μM and 0.17 μM , and 2.99 μM , respectively. hCA...
T9323	4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide	654-62-6	98%
T9323	4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide is a carbonic anhydrase inhibitor, used as a potential anti-tumor and antiglaucoma drug.
T25372	EMD57033	147527-31-9	98%
T25372	EMD57033 is a cardiac troponin C (cTnC) activator, a dominant Ca2+ sensitizer, which functions by binding to cardiac/slow skeletal troponin C heterodimers to pro...
T6781	Benzenesulfonamide	98-10-2	98%
T6781	Benzenesulfonamide ia an inhibitor of carbonic anhydrases.
T2134	Dorzolamide hydrochloride	130693-82-2	98%
T2134	Dorzolamide Hydrochloride is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid co...