T34093 |
PNNP
|
330-13-2
|
98%
|
|
pNNP can be used as a substrate for the PP2C assay. pNNP inhibits β-carbonic anhydrase and α-carbonate dehydrogenase, as well as H. pylori Helicobacter pylori. p...
|
T38808 |
Cyclamic acid sodium
|
139-05-9
|
98%
|
|
Cyclamic acid sodium is a carbonic anhydrase inhibitor and one of the most widely used artificial sweeteners in food and pharmaceuticals.Cyclamic acid sodium sho...
|
T77560 |
2-Amino-4-(4-chlorophenyl)thiazole
|
2103-99-3
|
98%
|
|
2-AMINO-4-(4-CHLOROPHENYL)THIAZOLE is a 2-aminothiazole derivative. 2-AMINO-4-(4-CHLOROPHENYL)THIAZOLE inhibited hCA I, hCA II, AChE and BChE with Ki values of 0...
|
T68136 |
5-Hexenoic acid, 6-[4-[2-[[(4-chlorophenyl)sulfonyl]amino]ethyl]phenyl]-6-(3-pyridinyl)-
|
133276-52-5
|
98%
|
|
5-Hexenoic acid, 6-[4-[2-[[(4-chlorophenyl)sulfonyl]amino]ethyl]phenyl]-6-(3-pyridinyl)- shows activity against Carbonic anhydrase and Cyclooxygenase 2.
|
T67775 |
Enpp/Carbonic anhydrase-IN-1
|
2883495-35-8
|
98%
|
|
Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent inhibitor of Enpp and carbonic anhydrase. Enpp/Carbonic anhydrase-IN-1 exhibits IC50s of 1.36, 1.35, 3.00,...
|
T6581 |
Methyclothiazide
|
135-07-9
|
98%
|
|
Methyclothiazide is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including heart disease.
|
T0515 |
Tioxolone
|
4991-65-5
|
98%
|
|
Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.
|
T23782 |
Benzolamide
|
3368-13-6
|
98%
|
|
Benzolamide is an inhibitor of carbonic anhydrase. Benzolamide inhibits low-threshold calcium currents in hippocampal pyramidal neurons.
|
T61745 |
HCAI/II-IN-6
|
694466-00-7
|
98%
|
|
hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA). hCAI/II-IN-6 inhibited hCA I, hCA II, hCA VII, and hCA XII with Ki valu...
|
T0738 |
Urea
|
57-13-6
|
98%
|
|
Urea is formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end metabolite of protein catabolism and accounts for ab...
|
T0675 |
Topiramate
|
97240-79-4
|
98%
|
|
Topiramate is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepat...
|
T36758 |
CAIX Inhibitor S4
|
1330061-67-0
|
98%
|
|
CAIX Inhibitor S4 is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively. The Kis for CA II and CA I are 546 and 5600 nM...
|
T21294 |
Polmacoxib
|
301692-76-2
|
98%
|
|
Polmacoxib is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant col...
|
T2S0357 |
6-Hydroxycoumarin
|
6093-68-1
|
98%
|
|
6-Hydroxycoumarin exhibits cytotoxicity against human HL60, HCT116, COLO205 cells with activity value of 35 uM, 42 uM, 37 respectively. 6-Hydroxycoumarin is a hu...
|
T6469 |
Dichlorphenamide
|
120-97-8
|
98%
|
|
Dichlorphenamide is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
|
T73177 |
HCAII-IN-9
|
2878477-18-8
|
98%
|
|
hCAII-IN-9 is a potent carbonic anhydrase inhibitor that inhibits hCA II, hCA IX, and hCA XII with IC50s of 1.18 μM and 0.17 μM , and 2.99 μM , respectively. hCA...
|
T9323 |
4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
|
654-62-6
|
98%
|
|
4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide is a carbonic anhydrase inhibitor, used as a potential anti-tumor and antiglaucoma drug.
|
T25372 |
EMD57033
|
147527-31-9
|
98%
|
|
EMD57033 is a cardiac troponin C (cTnC) activator, a dominant Ca2+ sensitizer, which functions by binding to cardiac/slow skeletal troponin C heterodimers to pro...
|
T6781 |
Benzenesulfonamide
|
98-10-2
|
98%
|
|
Benzenesulfonamide ia an inhibitor of carbonic anhydrases.
|
T2134 |
Dorzolamide hydrochloride
|
130693-82-2
|
98%
|
|
Dorzolamide Hydrochloride is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid co...
|