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CETP

Cholesteryl ester transfer protein (CETP), also called plasma lipid transfer protein, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. It collects triglycerides from very-low-density (VLDL) or low-density lipoproteins (LDL) and exchanges them for cholesteryl esters from high-density lipoproteins (HDL), and vice versa. Most of the time, however, CETP does a heteroexchange, trading a triglyceride for a cholesteryl ester or a cholesteryl ester for a triglyceride.
Cat. No. Product name CAS No. Purity Chemical Structure
T31992 Granotapide 594842-13-4 98%
Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic syn...
T15006 Dirlotapide 481658-94-0 98%
Dirlotapide is an intestinal selective microsomal triglyceride transfer protein (MTP) inhibitor. It reduces body weight in diabetic dogs.Dirlotapide reduces food...
T30506 BMS-212122 194213-64-4 98%
BMS-212122 is a potent inhibitor of microsomal triglyceride transfer protein (MTP ) and has shown hypolipidemic effects in animal studies.BMS-212122 significantl...
T13079 TAP311 T13079 98%
TAP311 is an inhibitor of cholesteryl ester transfer protein (CETP)(IC50 of 62 nM).
T13423 (1R,2R)-2-PCCA hydrochloride 1609563-71-4 98%
(1R,2R)-2-PCCA hydrochloride is a diastereomer of 2-PCCA, and is a potent agonist of GPR88 receptor(EC50 of 3 nM and 603 nM in cell-free assay and in cell assay)...
T15570 Implitapide 177469-96-4 98%
Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).
T15004 CP-532623 261947-38-0 98%
CP-532623, a close structural analog of Torcetrapib, is a CETP inhibitor with highly lipophilic properties. It elevates high-density lipoprotein cholesterol.
T2545 Lomitapide Mesylate 202914-84-9 98%
Lomitapide Mesylate is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein.
T6262 Evacetrapib 1186486-62-3 98%
Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood press...
T2499 Torcetrapib 262352-17-0 98%
Torcetrapib is a cholesteryl ester transfer protein (CETP) inhibitor that reduces the heterotypic transfer of cholesteryl ester from HDL to LDL and/or VLDL. Torc...
T1928 Anacetrapib 875446-37-0 98%
Anacetrapib (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer of...
T28225 Obicetrapib 866399-87-3 98%
Obicetrapib is an inhibitor of cholesteryl ester transfer protein.
T6267 Lomitapide 182431-12-5 98%
Lomitapide is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsib...
T6048 Dalcetrapib 211513-37-0 98%
Dalcetrapib, a rhCETP inhibitor (IC50=0.2 μM), increases the plasma HDL cholesterol.
T16266 NAMI-A 201653-76-1 98%
NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.
T27719 KD-026 913541-47-6 98%
KD-026, a microsomal triglyceride transfer protein (MTTP) inhibitor, is used potentially for the treatment of type 2 diabetes.
Granotapide
T31992
Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic syn...
Dirlotapide
T15006
Dirlotapide is an intestinal selective microsomal triglyceride transfer protein (MTP) inhibitor. It reduces body weight in diabetic dogs.Dirlotapide reduces food...
BMS-212122
T30506
BMS-212122 is a potent inhibitor of microsomal triglyceride transfer protein (MTP ) and has shown hypolipidemic effects in animal studies.BMS-212122 significantl...
TAP311
T13079
TAP311 is an inhibitor of cholesteryl ester transfer protein (CETP)(IC50 of 62 nM).
(1R,2R)-2-PCCA hydrochloride
T13423
(1R,2R)-2-PCCA hydrochloride is a diastereomer of 2-PCCA, and is a potent agonist of GPR88 receptor(EC50 of 3 nM and 603 nM in cell-free assay and in cell assay)...
Implitapide
T15570
Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).
CP-532623
T15004
CP-532623, a close structural analog of Torcetrapib, is a CETP inhibitor with highly lipophilic properties. It elevates high-density lipoprotein cholesterol.
Lomitapide Mesylate
T2545
Lomitapide Mesylate is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein.
Evacetrapib
T6262
Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood press...
Torcetrapib
T2499
Torcetrapib is a cholesteryl ester transfer protein (CETP) inhibitor that reduces the heterotypic transfer of cholesteryl ester from HDL to LDL and/or VLDL. Torc...
Anacetrapib
T1928
Anacetrapib (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer of...
Obicetrapib
T28225
Obicetrapib is an inhibitor of cholesteryl ester transfer protein.
Lomitapide
T6267
Lomitapide is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsib...
Dalcetrapib
T6048
Dalcetrapib, a rhCETP inhibitor (IC50=0.2 μM), increases the plasma HDL cholesterol.
NAMI-A
T16266
NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.
KD-026
T27719
KD-026, a microsomal triglyceride transfer protein (MTTP) inhibitor, is used potentially for the treatment of type 2 diabetes.