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xy1

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  • Inhibitors & Agonists
    4
    TargetMol | Inhibitors_Agonists
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    TargetMol | Natural_Products
XY1
T71571624117-53-8
XY1 is a close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of PRMT3 with IC50 of 31 nM), intended as a negative control for SGC707 in studies involving PRMT3 action.
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TargetMol | Inhibitor Sale
XY101
T133622349368-16-5In house
XY101 is a selective, metabolically stable and orally available agonist of RORγ inverse(IC50 of 30 nM and a Kd of 380 nM).
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6-8 weeks
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XY153
T63924
XY153 (compound 8l) is a BD2-selective BET inhibitor that binds BRD4 BD2 with an IC50 of 0.79 nM, BRD3 BD2 with an IC50 of 5.31 nM, and BRD2 BD2 with an IC50 of 5.09 nM. XY153 is used to study acute myeloid leukaemia and cancer.
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10-14 weeks
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(19R,23E)-5b,19-Epoxy19-ethoxycucurbita-6,23-diene-3b,25-diol
T835781301267-02-6
(19R,23E)-5b,19-Epoxy-19-ethoxycucurbita-6,23-diene-3b,25-diol, a cucurbitane-type triterpenoid, exhibited no activity against five cancer cell lines—MCF-7, HepG2, Du145, Colon205, and HL-60—when evaluated using the MTT assay [1].
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