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  • Inhibitors & Agonists
    96
    TargetMol | Inhibitors_Agonists
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    TargetMol | Inhibitors_Agonists
yGsy2p-IN-1
T87032415003-97-1
yGsy2p-IN-1 is a potent inhibitor of yeast glycogen synthase 2 (yGsy2p) and human glycogen synthase 1 (hGYS1). Additionally, yGsy2p-IN-H23, a pyrazole inhibitor, is utilized in the treatment of glycogen storage diseases (GSDs).
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Sinbaglustat
ACT-519276, Sinbaglustat, OGT2378
T40542441061-33-2In house
Sinbaglustat (OGT2378) (OGT2378) is a dual inhibitor of glucose ceramide synthetase (GCS) and non-lysosomal glucose ceramidase (GBA2).Sinbaglustat is an orally administered N-alkyl iminosugar that crosses the blood-brain barrier.Sinbaglustat is used for the treatment of lysosomal storage disorders and for the study of central neurodegenerative disorders associated with lysosomal dysfunction. Sinbaglustat is used for the treatment of lysosomal storage disorders and for the study of lysosomal dysfunction-related central neurodegenerative diseases.
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D-Galactose
D-Galactopyranose, D-(+)-Galactose, Alpha-D-galactose
T059159-23-4
D-Galactose (Alpha-D-galactose) is an aldohexose that exists naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins and is converted enzymatically into D-glucose for metabolism or polysaccharides for storage. It accelerates senescence in invertebrates and mammals and has been used as a model for aging.
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Tetrabenazine
Xenazine, Ro 1-9569
T071958-46-8
Tetrabenazine (Ro 1-9569) is a former antipsychotic drug used to treat various movement disorders. It inhibits neurotransmitter uptake into adrenergic storage vesicles and serves as a high-affinity label for the vesicle transport system.
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Multifungin
Bromochlorosalicylanilide, Salifungin
T10433679-64-9
Multifungin (Bromochlorosalicylanilide) is an antifungal agent used in studies of oral candidiasis, reducing fungal populations in stored corn and preventing zearalenone formation and accumulation.
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ATP disodium salt
Disodium adenosine triphosphate, ATP disodium, ATP, Adetide, Adenosine-Triphosphate, Adenosine 5'-triphosphate disodium salt
T1352987-65-5
ATP disodium salt (Adenosine-Triphosphate) is a P2 purinoceptor agonist.
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Phytic acid dodecasodium salt hydrate
myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate, Inositol hexaphosphate dodecasodium salt hydrate
T16527123408-98-0
Phytic acid dodecasodium salt hydrate (myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate) is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium salt hydrate inhibits the enzymatic superoxide source xanthine oxidase with an IC50 of 6 mM and has antioxidative, neuroprotective, and anti-inflammatory effects.
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4-6 weeks
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Edetic acid
Ethylenediaminetetraacetic acid, EDTA
T2047060-00-4
Edetic acid (Ethylenediaminetetraacetic acid) is a chelating agent commonly used in protein purification, both to eliminate contaminating divalent cations and to inhibit protease activity.
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Phytic acid sodium salt
Sodium phytate hydrate
T558414306-25-3
Phytic acid sodium salt (Sodium phytate hydrate) is known to function as a [PO4]3- storage depot and a precursor for other inositol phosphates and pyrophosphates. It is a potent chelator of divalent and trivalent cations in vitro.
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ATP disodium trihydrate
Adenosine-5'-triphosphate disodium trihydrate
T6498051963-61-2
ATP disodium trihydrate (Adenosine-5'-triphosphate disodium trihydrate) is an important substance for energy storage and metabolism in the body. It is an important endogenous signaling molecule in immunity and inflammation, which provides energy for the body's metabolism and also acts as a coenzyme in cells.
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7-10 days
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Docosane
TN6962629-97-0
Docosane [Standard Material for GC] is a natural product.
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NKH477
NKH 477, Colforsin dapropate hydrochloride
T16332138605-00-2
NKH477 (Colforsin dapropate hydrochloride) is a derivative of forskolin with antidepressant activity. It inhibits ACh-induced Ca2+ mobilization by acting on ionomycin-sensitive storage sites. NKH477 is an adenylyl cyclase activator with bronchodilatory effects, inhibiting the production of CTL, T-cell proliferation in mixed lymphocyte reactions (MLR), as well as IL-2 production and mitogen responses.
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7-10 days
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Ibiglustat
Venglustat, SAR402671, GZ402671
T44731401090-53-6
Ibiglustat (GZ402671) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation of glucosylceramide (GL-1), a key intermediate in the synthesis of GL-3. Ibiglustat is potentially useful for treating Fabry disease. Fabry disease is a rare lysosomal storage disorder, which results in abnormal tissue deposits of a particular fatty substance called globotriaosylceramide (GL-3 or Gb3) throughout the body.
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Reserpine
Serpivite, Serpasil, Serpalan
T079150-55-5
Reserpine (Serpalan) is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
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IFB-088 acetate
T111959469866-31-7
IFB-088 acetate, a benzyl guanidine derivative, is used to treat diseases and cancers associated with the PPP1R15A pathway and associated with protein misfolding stress, Examples include tau disease, synaptic riboprotein disease, polyglutamine and polyalanine diseases, leukodystrophy, cystic fibrosis, multiple sclerosis, lysosome storage disorders, amyloidosis diseases, inflammation, metabolic disorders, cardiovascular diseases, osteoporosis, neurological trauma, and more.
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Selenomethionine
DL-Selenomethionine, Seleno-DL-methionine
T16581464-42-2
DL-Selenomethionine (Seleno-DL-methionine) is a selenium (Se) analogue of methionine in which sulfur is replaced with the trace element selenium. Selenomethionine (SeMet) can incorporate into proteins in place of methionine with no effects on protein structure and function, providing a mechanism for reversible Se storage in organs and tissues.
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D-Glucose 6-phosphate
Glucose 6-phosphate, G6P
T1926356-73-5
D-Glucose 6-phosphate (G6P) is glucose that hydroxyl group on carbon 6 is phosphorylated by hexose kinase and is involved in glycolysis, gluconeogenesis, and the pentose phosphate pathway, as well as being converted to glycogen or starch storage. G6P serves as a substrate for glucose 6-phosphatase in the liver and hexose 6-phosphate dehydrogenase (H6PDH) in the lumen of the endoplasmic reticulum.
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D-Methionine sulfoxide hydrochloride
D-Methionine sulfoxide hydrochloride (21056-56-4 free base)
T19264
D-methionine sulfoxide hydrochloride is the D-isomer of methionine sulfoxide hydrochloride, the oxidation product of methionine, a restrictive amino acid in milk or legume proteins that is easily oxidized during storage or processing.
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4-6 weeks
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Glycogen, Mussel
T193449005-79-2
Glycogen, Mussel is a glycolytic intermediate and high-energy phosphate that ACTS as a form of energy storage for humans, animals, fungi and bacteria.
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8-Hydroxygenistein
8-OHG
T20329213539-27-0
8-Hydroxygenistein (8-OHG) is an antioxidant that effectively scavenges NO and O2-. It is a type of ortho-dihydroxyisoflavone (ODI) and is abundantly found in thick and fermented soy sauces, exhibiting stronger antioxidant properties than its parent compound, Genistein. The concentration of 8-Hydroxygenistein is positively correlated with the antioxidant capacity of soy sauce (r=0.959) and maintains high stability even after being heated in boiling water for 60 minutes. It is effective in preventing oxidative damage during the brewing and storage of soy sauce, offering potential applications in food antioxidant research.
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EDTA tetrasodium tetrahydrate
T20370813235-36-4
EDTA tetrasodium tetrahydrate is a metal chelator known for its ability to bind with divalent and trivalent metal cations, including calcium. It exhibits antihypercalcemic and anticoagulant properties. This compound reduces metal ion-catalyzed oxidative damage to proteins and maintains a reducing environment during protein purification processes, making it commonly used for protein purification and storage. Additionally, it helps in minimizing the formation of disulfide bonds.
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Pirimiphos-methyl
R 33986, AI3-27699, Caswell No. 334B, PP511, Actelic
T2053929232-93-7
Pirimiphos-methyl (AI3-27699) is a rapid-acting organophosphorus insecticide and acaricide, causing inhibition of AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, moths, snout beetles and Ephestia cautella during storage of agricultural grains.
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Reserpine hydrochloride
Serpivite hydrochloride, Serpasil hydrochloride, Serpalan hydrochloride
T2177216994-56-2
Reserpine hydrochloride (Serpivite hydrochloride) is the salt form of Reserpine, an alkaloid that inhibits the uptake of norepinephrine into storage vesicles, leading to depletion of catecholamines and serotonin in central and peripheral axon terminals, with antihypertensive and antipsychotic potential.
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7-10 days
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Tetrabenazine methanesulfonate
NSC169886,NSC 169886,NSC-169886
T26260804-53-5
Tetrabenazine methanesulfonate is a medicine formerly utilized as an antipsychotic and therapy for various movement disorders. Tetrabenazine methanesulfonate blocks neurotransmitter uptake into adrenergic storage vesicles and has been used as a high-affin
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1-2 weeks
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