p51 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T16831	(S)-SNAP5114		Others , GABA Receptor
	(S)-SNAP5114 is a selective inhibitor of GABA transport with IC50s of 5 μM for hGAT-3 and 21 μM for rGAT-2. (S)-SNAP5114 has anticonvulsant properties.		Others , GABA Receptor
T79739	CYP51/PD-L1-IN-2
	CYP51/PD-L1-IN-2 (compound L20), a quinazoline with antifungal properties, is a potent dual inhibitor targeting both CYP51 (IC50: 0.263 μM) and PD-L1 (IC50: 0.017 μM). The compound promotes early apoptosis in the fungal ...
T16334	NMS-P515		Others
	NMS-P515 is an effective, orally active, and stereospecific PARP-1 inhibitor (Kd: 16 nM and an IC50: 27 nM (in Hela cells)). It has anti-tumor activity.		Others
T27097	CTP518	CTP 518,Deuterated Atazanivir-D3-1,CTP-518
	CTP518, a deuterated Atazanivir derivative, is a HIV protease inhibitor.
T24914	UBP512	UBP 512,UBP-512
	UBP512 is a NMDA receptor modulator.
T78902	CYP51/PD-L1-IN-4
	CYP51/PD-L1-IN-4 (compound 14a-2) is a potent dual-target inhibitor of CYP51/PD-L1, displaying IC50 values of 0.17 and 0.021 μM, respectively. This compound demonstrates significant antifungal efficacy and combats drug-r...
T64154	CYP51/HDAC-IN-1
	CYP51/HDAC-IN-1 is an orally active, potent, dual CYP51/HDAC inhibitor that inhibits important virulence factors and down-regulates the expression of associated drug resistance genes.CYP51/HDAC-IN-1 has shown effective t...
T79184	FKBP51F67V-selective antagonist Ligand2		FKBP
	FKBP51F67V-selective antagonist Ligand2 (example 3-3), a potent ligand, selectively binds to the FKBP51 F67V variant, with no affinity for wild-type FKBP51 or FKBP52 [1]. It effectively reverses the anxiogenic phenotype ...		FKBP
T79740	CYP51/PD-L1-IN-3
	CYP51/PD-L1-IN-3 (compound L21), a quinazoline with antifungal properties, serves as a dual inhibitor targeting CYP51 (IC50: 0.205 μM) and PD-L1 (IC50: 0.039 μM). This compound promotes early fungal apoptosis within the ...
T79738	CYP51/PD-L1-IN-1
	CYP51/PD-L1-IN-1 (compound L11), a quinazoline with antifungal properties, simultaneously inhibits CYP51 (IC50: 0.884 μM) and PD-L1 (IC50: 0.083 μM). This compound prompts early apoptosis in the fungal cell cycle, marked...
T70878	P516-0475
	P516-0475 is a novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO. This compound induces quorum sensing by stabilizing SHP pheromones in culture.

Compounds

(S)-SNAP5114

T16831

Synonym:

Target: Others, GABA Receptor

Synonym: CTP 518,Deuterated Atazanivir-D3-1,CTP-518

Target:

UBP512

T24914

Synonym: UBP 512,UBP-512

FKBP51F67V-selective antagonist Ligand2

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04150	HIV-p51/RT-p51 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His)	HIV	E. coli
	HIV-p51/RT-p51 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 53.6 kDa and the accession number is P04585.
TMPY-02651	P63 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Tumor protein p63 is a protein also known as transformation-related protein 63, TP63, and p63. Tumor protein p63 / p63 is a member of the p53 family of transcription factors whose members P53, p63, and p73 have similar f...
TMPH-03017	CYP51 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)	Mycobacterium tuberculosis	Baculovirus Insect Cells
	Its precise biological substrate is not known. Catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethy...