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  • glycosidase
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Results for "

glycosidase

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    39
    TargetMol | Inhibitors_Agonists
  • Natural Products
    9
    TargetMol | Natural_Products
  • Recombinant Protein
    3
    TargetMol | Recombinant_Protein
  • Cell Research
    1
    TargetMol | Inhibitors_Agonists
Glycosidase-IN-1
T11430170376-12-2
Glycosidase-IN-1 is a glycosidase inhibitor synthesized from D-mannose with hypoglycemic activity. It can be used to synthesize some immunosuppressive agents and β-glucosidase inhibitors.
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8-10 weeks
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Glycosidase-IN-2
T11431476310-39-1
Glycosidase-IN-2 is a glycosidase inhibitor with hypoglycemic activity.
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8-10 weeks
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β-glycosidase-IN-1
T13478176485-27-1
β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.
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6-8 weeks
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α-Glycosidase-IN-2
T201070
α-Glycosidase-IN-2 (compound 8b) is an inhibitor of α-glycosidase, displaying Ki values of 74.16 nM and 6.09 nM for aldose reductase and α-glycosidase, respectively. This compound is utilized in research related to diabetes.
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α-Glycosidase-IN-1
T639412428389-66-4
α-Glycosidase-IN-1 (compound MZ7) is a potent inhibitor of α-GLY (α-glycosidase) with an IC50 of 44.72 nM and a Ki of 44.74 nM. It also inhibits human carbonic anhydrase isozymes I (hCA I) and II (hCA II) with IC50 values of 104.87 nM and 100.04 nM, respectively, and acetylcholine esterase (AChE) with an IC50 value of 654.87 nM. α-Glycosidase-IN-1 is applicable in the study of diabetes, Alzheimer's disease, ulcers, heart failure, epilepsy, and various other diseases.
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6-8 weeks
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Terrestrimine
TN89471778735-31-1
Terrestrimine is a potent glycosidase inhibitor with an IC50 of 225.83 μM. It plays a significant role in the study of metabolic diseases.
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Resinacein L
T2033682259327-01-8
Resinacein L is an inhibitor of α-glucosidase with an IC50 of 0.635 mM. This compound can slow the digestion and absorption of carbohydrates, thereby reducing postprandial blood glucose levels.
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α-Glucosidase-IN-76
T203476
α-Glucosidase-IN-76 (Compound 4r) is an inhibitor of α-glucosidase, with an IC50 of 5.44 μM. It can clear ABTS+ free radicals, with a TEAC value of 0.49. Additionally, α-Glucosidase-IN-76 inhibits the proliferation of T24 bladder cancer cells, with an IC50 of 1.74 μM.
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α-Glucosidase-IN-77
T203496
α-Glucosidase-IN-77 (Compound H7) is a non-competitive α-glucosidase inhibitor with an IC50 of 1.25 μM. It reduces blood glucose levels, improves glucose tolerance, regulates gut microbiota, and exhibits hepatoprotective effects in a mouse model of type 2 diabetes.
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α-Glucosidase-IN-83
T204116
α-Glucosidase-IN-83 (compound I-1) is a potent inhibitor of α-glucosidase, demonstrating an IC50 of 1.49 μg mL. This compound effectively reduces blood glucose levels in vivo.
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α-Glucosidase-IN-82
T204291
α-Glucosidase-IN-82 (compound 8l) is a potent inhibitor of α-glucosidase, with an IC50 value of 13.66 μM. Its inhibitory activity is 52 times greater than that of Acarbose.
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α-Glucosidase-IN-78
T204369
α-Glucosidase-IN-78 (Compound 12m) is a reversible competitive inhibitor of α-glucosidase (α-glucosidase) with an IC50 of 6.0 μM. Due to its blood sugar-lowering properties, α-Glucosidase-IN-78 is applicable in diabetes research.
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α-Glucosidase-IN-79
T204466
α-Glucosidase-IN-79 (Compound 4d9) is a non-competitive α-glucosidase inhibitor with an IC50 of 2.11 μM, demonstrating greater inhibitory potency than the existing α-glucosidase inhibitors Acarbose (IC50 of 327.0 μM) and HXH8r (IC50 of 15.32 μM). It exhibits no cytotoxicity on normal human liver cells (LO2) and shows good metabolic stability in rat plasma. α-Glucosidase-IN-79 holds promise for research in type 2 diabetes.
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α-Amylase/α-Glucosidase-IN-18
T205013
α-Amylase α-Glucosidase-IN-18 (Compound 9g) is an inhibitor of α-amylase and α-glucosidase, with IC50 values of 49.17 nM and 10.71 nM, respectively. It is suitable for research related to type 2 diabetes.
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α-Amylase/α-Glucosidase-IN-17
T205124
α-Amylase α-Glucosidase-IN-17 (Compound 3) is an inhibitor of α-amylase and α-glucosidase, with IC50 values of 14.61 μM and 25.38 μM, respectively. It exhibits some inhibitory activity against A549 cancer cells and possesses both antitumor and antidiabetic properties.
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α-Amylase-IN-12
T2055051799667-33-6
α-Amylase-IN-12 (Compound 5e) is an α-amylase inhibitor with an IC50 of 0.15 mM, functioning through a mixed inhibition mode. It exhibits an IC50 of 9.40 mM against α-glucosidase. This compound enhances glucose uptake in yeast cells and demonstrates significant anti-glycation activity at high concentrations. α-Amylase-IN-12 is applicable for diabetes research.
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10-14 weeks
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α-Glucosidase-IN-84
T205575
α-Glucosidase-IN-84 (Compound 7j) is a competitive inhibitor of α-glucosidase, exhibiting an IC50 of 50 μM and a Ki of 32 μM. It shows potential for application in metabolic disease research, particularly in studies related to type 2 diabetes.
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α-Glucosidase-IN-80
T205662
α-Glucosidase-IN-80 (Compound 10n) is a potent competitive inhibitor of α-glucosidase, with an IC50 of 48.4 μM. It exhibits favorable pharmacokinetic properties and toxicity profiles, making it suitable for research in diabetes-related conditions.
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Adiposin
TN900283764-11-8
Adiposin is a microbial metabolite that acts as an inhibitor of α-glucoside hydrolase (α-glucosidase).
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Fagomine
D-Fagomine
TQ029853185-12-9
Fagomine (D-Fagomine) is a mild glycosidase inhibitor, an analog of 1-deoxynojirimycin (DNJ) with hypoglycemic activity, and Fagomine reduces intracellular reactive oxygen species (ROS) production and malondialdehyde (MDA) levels.
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7-10 days
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4-Methylumbelliferyl-α-D-Glucopyranoside
4-MU-α-D-Glucopyranoside, 4-Methylumbelliferyl-α-D-Glucoside, 4-Methylumbelliferyl-α-D-Glucose
T8513417833-43-1
4-Methylumbelliferyl-α-D-Glucopyranoside (4MU-αGlc) is a pH-dependent α-glucosidase fluorometric substrate, a biomarker for Fabry and Pompe diseases, quantifying α-glucosidase activity in infant blood spots.
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8-10 weeks
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Glucobrassicin
TN84324356-52-9
Glucobrassicin is a glucosinolate (GSL) that can be isolated from wild carrot (Raphanus raphanistrum L.). It is utilized in research on biofumigation or allelopathic plants for weed management.
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Isoeugenol acetate
Isoeugenyl acetate, Acetisoeugenol, Acetylisoeugenol
T2S049193-29-8
1. Isoeugenol acetate (Acetylisoeugenol) shows good antifungal activities against R. solani and F. oxysporum. 2. Isoeugenol acetate is a mild sensitizer in vivo.
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(-)-vibo-Quercitol
(-)-Viburnitol
T3766488-76-6
(-)-vibo-Quercitol ((-)-Viburnitol) is a carbaglycosylamine glycosidase inhibitor.
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