farnesyl

Farnesyl Pyrophosphate ammonium (Farnesyl diphosphate ammonium) is a metabolic intermediate of the MVA pathway that acts as a newly identified danger signal to trigger acute cell death and induce neuronal loss in stroke.

Farnesyl acetate (Farnesyl Acetate (mixture of isomers)) is a flavouring compound identified in foods such as blueberries.

(ZE)-Farnesyl Pyrophosphate ammonium salt is an isomer of (E,E)-Farnesyl Pyrophosphate ammonium salt, which is a key metabolic intermediate in the mevalonate (MVA) pathway and an agonist of TRPM2, and is involved in cholesterol synthesis, ubiquinone synthesis, protein farnesylation and other physiological processes.

α-hydroxy Farnesyl phosphonic acid, a nonhydrolyzable analog of farnesyl pyrophosphate, acts as a competitive inhibitor of farnesyl transferase (FTase). At concentrations above 1 μM, it inhibits the processing of Ras in Ha-ras-transformed NIH3T3 cells.

S-Farnesyl thioacetic acid, an analog of S-farnesyl cysteine, acts as a competitive inhibitor of isoprenylated protein methyltransferase (S-adenosylmethionine-dependent methyltransferase) and inhibits the methylation of both farnesylated and geranylgeranylated substrates.

Farnesyl pyrophosphate (Farnesyl diphosphate), a 15-carbon isoprenoid from the mevalonate (MVA) pathway, functions as a metabolic intermediary and TRPM2 (TRP Channel) agonist, facilitating TRPM2 channel opening and ion influx. It is crucial in synthesizing cholesterol, ubiquinones, and geranyl-geranyl pyrophosphate (GGPP), and in protein farnesylation decoration [1].

Farnesylacetone ((5E,9E)-6,10,14-Trimethylpentadeca-5,9,13-trien-2-one) is a marine derived natural products found in Sargassum micracanthum.

Monofarnesyl phosphate is a farnesyl that may be used to study the metabolism of proteins and enzymes related to organic synthesis and biological experiments.Farnesyl is the simplest sesquiterpene formed by the condensation of three isoprene units in the isoprenoid biosynthetic pathway.

p-O-Farnesylcoumaric acid is a useful organic compound for research related to life sciences and the catalog number is T123900.

Prednisolone farnesylate is a novel transdermal corticosteroid with anti-inflammatory activity.

Farnesylthiotriazole is a persistent PKC activator agent.

(8'α,9'β-Dihydroxy)-3-farnesylindole exhibits significant inhibitory effectiveness (EC50 9.8 μM) against B. subtilis.

Hexahydrofarnesyl acetone (Phytone) enhanced both the sticky materials production and cell growth, plays some role in the increase of sticky materials and cell growth.

Farnesylcysteine (FC) serves as a competitive inhibitor of ICMT and is associated with an ABA hypersensitive phenotype in Arabidopsis thaliana. The fcly mutant exhibits reduced farnesylcysteine (FC) lyase activity and shows an increased response to ABA [1].

(2Z,6Z,10E,14E,18E)-Farnesylfarnesol is a natural product for research related to life sciences. The catalog number is TN5828 and the CAS number is 90695-03-7.

ABT-100 is a potent, highly selective, and orally active inhibitor of farnesyl transferase [farnesyl-protein transferase] with broad-spectrum antitumor activity.

Prenyl-IN-1 is a potent and selective prenylation inhibitor of geranylgeranyltransferase or farnesyltransferase.Prenyl-IN-1 shows anti-oxidative stress effects in a Parkinson's model. Prenyl-IN-1 showed anti-oxidative stress in a Parkinson's model.

BMS-214662 is a selective farnesyl transferase inhibitor with antitumor activity, useful in studies of pancreatic, head and neck, and lung cancers.

BPH-1358 (NSC-50460) (NSC-50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. With IC50s of 1.8 μM and 110 nM, respectively. And it is active against S. aureus in vitro (MIC ~250 ng mL)[1][2].

A-176120 ammonium is a novel farnesyl pyrophosphate analog with antitumor and antiangiogenic properties and inhibits farnesyltransferase activity.

LB42708 is an orally active farnesyltransferase (FTase) inhibitor (IC50: 0.8 1.2 2.0 nM toward H N K-ras).

L-739750 2HCl is a potent inhibitor of peptidomimetic farnesyltransferase, a novel pseudopeptide mimetic with potential anticancer activity.

C15AlkOPP Tetrabutylamine salt is a clickable alkyne-modified analogs of the lipid substrates farnesyl diphosphate (FPP).

Risedronic Acid (Risedronate), a pyridinyl biphosphonate, can inhibit osteoclast-mediated bone resorption.