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Results for "

antibody-drug conjugates linkers

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    79
    TargetMol | Inhibitors_Agonists
  • Peptide Products
    2
    TargetMol | Peptide_Products
  • PROTAC Products
    74
    TargetMol | PROTAC
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    2
    TargetMol | Natural_Products
N-Hydroxysulfosuccinimide sodium
T16225106627-54-7
N-Hydroxysulfosuccinimide sodium is a non-cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis.
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SMCC
N-Succinimidyl 4-(N-maleimidomethyl)cycl
T911664987-85-5
SMCC (N-Succinimidyl 4-(N-maleimidomethyl)cycl) is a heterobifunctional protein crosslinker.
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Propargyl-PEG3-acid
T166051347760-82-0
Propargyl-PEG3-acid is a non-cleavable (3-unit PEG) ADC linker and a PEG-based PROTAC linker, used to synthesize 6-OHDA-PEG3-yne, a compound containing 6-OHDA and Propargyl-PEG3-acid[1].
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Ald-Ph-NHS ester
T1737260444-78-2
Ald-Ph-NHS ester is a non-cleavable linker utilized in antibody-drug conjugation (ADC).
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AMAS
T1738955750-61-3
AMAS is a non-claevable heterobifunctional crosslinker with NHS ester and maleimide groups that enables covalent conjugation of amine- and sulfhydryl-containing molecules.
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Boc-NH-C6-Br
T17654142356-33-0
Boc-NH-C6-Br is a cleavable linker used in antibody-drug conjugates (ADC).
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Mc-​Val-​Ala-​PAB
Mc-Val-Ala-PAB
T42891870916-87-2
Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC).
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MC-Val-Cit-PAB
T5149159857-80-4
MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.
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BS3 Crosslinker disodium
T14833L127634-19-9
BS3 Crosslinker disodium, a non-cleavable ADC linker, is employed in the synthesis of antibody-drug conjugates (ADCs).
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DBCO-amine
T150581255942-06-3
DBCO-amine is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].
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DOTA-​NHS-​ester
T17842170908-81-3
DOTA-NHS-ester is a linker for affibody molecules with applications in small animal PET, SPECT, and CT. It can be used to label radiotherapeutic agents or imaging probes for tumor detection.
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Sulfo-SMCC sodium
T1872892921-24-9
Sulfo-SMCC sodium, a widely utilized non-cleavable, hetero-bifunctional crosslinker for antibody-drug conjugates (ADCs), features both N-hydroxysuccinimide (NHS) ester and maleimide groups. These functionalities enable it to specifically react with primary amines and sulfhydryl groups, respectively.
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SPDB
T4346115088-06-7
SPDB is a degradable ADC linker that can be used to synthesize antibody-drug conjugates. SPDB is a small fragment attached to the DM4 conjugate and conjugated to the antibody using a disulfide bond.
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Boc-NH-PEG4-CH2COOH
T14746876345-13-0
Boc-NH-PEG4-CH2COOH is a cleavable ADC linker utilized in the development of antibody-drug conjugates (ADC)[1].
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DSG Crosslinker
T1517179642-50-5
DSG Crosslinker, a cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs).
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DSP Crosslinker
T1517557757-57-0
DSP Crosslinker, used in antibody-drug conjugates (ADCs) synthesis, is a cleavable ADC linker[1].
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DSS Crosslinker
T1517668528-80-3
DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is a homobifunctional crosslinker that is cell membrane permeable, with amine-reactive NHS esters at both ends of an 8-atom [11.4 angstrom] spacer arm for conjugating proteins, including intracellular proteins.
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7-10 days
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Fmoc-8-amino-3,6-dioxaoctanoic acid
Fmoc-NH-PEG2-CH2COOH
T15304166108-71-0
Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and a PEG-based PROTAC linker for the synthesis of PROTACs.
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Boc-Val-Cit-OH
T17691870487-08-4
Boc-Val-Cit-OH is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs).
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Fmoc-Gly-Gly-OH
T1795235665-38-4
Fmoc-Gly-Gly-OH, a cleavable ADC linker, can be used in the synthesis of antibody-drug conjugates (ADCs).
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NH-bis(C1-Boc)
T1847985916-13-8
NH-bis(C1-Boc) is an uncleavable linker used for antibody-drug conjugates (ADC).
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Succinic anhydride
T18723108-30-5
Succinic anhydride is a cyclic anhydride. Succinic anhydride acts as a nonclaevable ADC linker. Succinic anhydride can react with compound 4 to link the prodrug to an amine or hydroxy 1 group of a targeting polypeptide.
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Fmoc-Lys-OH hydrochloride
T41312139262-23-0
Fmoc-Lys-OH hydrochloride is an alkyl-chain-based PROTAC linker and a non-cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs).
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Boc-C16-COOH
T9783843666-40-0
Boc-C16-COOH is a alkyl-chain-based PROTAC linker. Boc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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