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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8730 | BMS986260 | TGF-beta/Smad | |
BMS-986260 is a selective, and orally bioavailable TGFβR1 inhibitor(IC50 = 1.6 nM). | |||
T14569 | BI8626 | E1/E2/E3 Enzyme | |
BI8626 is a ubiquitin ligase HUWE1 inhibitor with protective effects against spontaneous desiccation syndrome in NOD/ShiLtj mice.BI8626 inhibits intracellular cholesterol and decreases the expression of phosphorylated ZA... | |||
T73689 | Daclizumab | Ro 24-7375,Zenapax | IL Receptor |
Daclizumab (Zenapax) is a humanized monoclonal antibody that specifically inhibits the alpha subunit of IL-2R-HA. Daclizumab (Zenapax) can inhibit the binding of IL-2 and IL-2R-HA through specific binding to CD25. Dacliz... | |||
T80854 | Vopikitug | ||
Vopikitug, a human IgG1-kappa monoclonal antibody targeting the IL2RA (interleukin 2 receptor alpha subunit, IL-2RA, TAC, p55, CD25), exhibits antineoplastic activity [1]. | |||
T76770 | Camidanlumab | ||
Camidanlumab (HuMax-TAC), a CD25 monoclonal antibody, selectively binds to the cell-surface antigen CD25, prevalent on numerous hematological tumors but minimally present on normal tissues. This specificity facilitates i... | |||
T73697 | Denileukin diftitox | ||
Denileukin diftitox (DAB 389IL-2), a fusion protein toxin combining diphtheria toxin (DT) and interleukin 2 (IL-2), selectively depletes cells with the high-affinity IL-2 receptor (IL-2R), specifically CD25. By binding t... | |||
T25050 | Alloferon 3 | ||
Alloferon 3 is a natural peptide that mediates signaling by the NF-kappa B pathway to enhance the recognition of viral and tumor antigens. It is known to induce the production of endogenic interferons that promote a casc... | |||
T81308 | RDN2150 | ||
RDN2150 (Compound 25), a ZAP-70 inhibitor with an IC50 of 14.6 nM, covalently binds to the C346 residue of ZAP-70, suppressing the expression of CD25 and CD69 and inhibiting the activation of CD4+ T cells, making it suit... |