T16667 |
PROTAC Sirt2 Degrader-1
|
2098487-75-1
|
98%
|
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PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a b...
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T17249 |
VZ185
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2306193-61-1
|
98%
|
|
VZ185 is an effective and selective dual BRD7/9 PROTAC degrader (DC50s: 4.5 and 1.8 nM, respectively).
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T11292 |
FKBP12 PROTAC dTAG-7
|
2064175-32-0
|
98%
|
|
FKBP12 PROTAC dTAG-7 (dTAG-7) is a heterobifunctional compound that selectively degrades the BET bromodomain transcriptional co-activator BRD4 by connecting BET ...
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T5438 |
PROTAC CDK9 Degrader-1
|
2118356-96-8
|
98%
|
|
PROTAC CDK9 Degrader-1 is a selective CDK9 degrader.
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T13839 |
PROTAC ER Degrader-4
|
2361114-15-8
|
98%
|
|
PROTAC ER Degrader-4 is a PROATC degrader of estrogen receptor (ER)(IC50 of 0.8 nM).
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T11664 |
INY-03-041
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T11664
|
98%
|
|
INY-03-041, a potent and highly selective PROTAC-based pan-AKT degrader, inhibits AKT1, AKT2, and AKT3 with IC50s of 2.0 nM, 6.8 nM, and 3.5 nM, respectively. Th...
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T12556 |
PROTAC B-Raf degrader 1
|
2364367-27-9
|
98%
|
|
PROTAC B-Raf degrader 1 is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf,PROTAC B-Raf degrader 1 With anti-cancer activity.
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T13846 |
PROTAC RIPK degrader-2
|
1801547-16-9
|
98%
|
|
PROTAC RIPK degrader-2 is a nonpeptidic PROTAC ,and potently targets serine-threonine kinase RIPK2 and has highly selective for RIPK2 degradation.
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T13849 |
PROTAC BET Degrader-1
|
2093386-22-0
|
98%
|
|
PROTAC BET Degrader-1 is a potent degrader of BET based on PROTAC.
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T18631 |
PROTAC MDM2 Degrader-1
|
2249944-98-5
|
98%
|
|
PROTAC MDM2 Degrader-1 is a chemical compound that utilizes PROTAC technology to degrade MDM2. This compound is comprised of a highly effective MDM2 inhibitor, a...
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T18633 |
PROTAC MDM2 Degrader-3
|
2249750-23-8
|
98%
|
|
PROTAC MDM2 Degrader-3 is a compound that leverages PROTAC technology to degrade MDM2. It consists of a highly effective MDM2 inhibitor, a linker, and the MDM2 l...
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T18607 |
PROTAC ER Degrader-3
|
2158322-29-1
|
98%
|
|
PROTAC ER Degrader-3, an intermediate for the synthesis of PAC, specifically compound LP2. PAC serves as the linker for ADCs and PROTACs that are conjugated to a...
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T17910 |
(S,R,S)-AHPC-PEG2-C4-Cl
|
1835705-57-1
|
98%
|
|
(S,R,S)-AHPC-PEG2-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-PEG2-C4-Cl is capa...
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T17911 |
(S,R,S)-AHPC-C6-PEG3-C4-Cl
|
1835705-55-9
|
98%
|
|
(S,R,S)-AHPC-C6-PEG3-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl i...
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T13842 |
PROTAC IRAK4 degrader-1
|
2360533-90-8
|
98%
|
|
PROTAC IRAK4 degrader-1 is a degrader of PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4).
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T13835 |
PROTAC BRD4 Degrader-3
|
2313234-00-1
|
98%
|
|
PROTAC BRD4 Degrader-3 is an efficacious degrader of PROTAC BRD4.
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T13785 |
MZP-54
|
2010159-47-2
|
98%
|
|
MZP-54 is a selective degrader of BRD3/4 based on PROTAC technology(Kd of 4 nM for Brd4BD2)
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T14549 |
BETd-246
|
2140289-17-2
|
98%
|
|
BETd-246 is an inhibitor of second-generation and PROTAC-based BET bromodomain (BRD), show antitumor activity.
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T12560 |
PROTAC BRD9 Degrader-1
|
2097971-01-0
|
98%
|
|
PROTAC BRD9 Degrader-1 is a lead PROTAC BRD9 chemical degrader with IC50 of 13.5 nM.
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T16701 |
QCA570
|
2207569-08-0
|
98%
|
|
QCA570 is an effective BET degrader based on PROTAC (IC50: 10 nM for BRD4 BD1 Protein).
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