T11880 |
LSD1-IN-5
|
2035912-55-9
|
98%
|
|
LSD1-IN-5 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1. LSD1-IN-5 is a potent and reversible inhibitor of lysine-specific de...
|
T13745 |
KF21213
|
155271-17-3
|
98%
|
|
KF21213 shows a high affinity for the adenosine A2A receptors (Ki=3.0 nM). KF21213 is a highly selective ligand for mapping CNS adenosine A2A receptors.
|
T11756 |
Kgp-IN-1
|
2097865-36-4
|
98%
|
|
Kgp-IN-1 is an arginine-specific gingipain (Rgp) inhibitor.
|
T11503 |
GSK 690 Hydrochloride
|
2436760-79-9
|
98%
|
|
GSK 690 (Hydrochloride) is a reversible lysine specific demethylase 1 (LSD1) inhibitor with a Kd value of 9 nM and IC 50 of 37 nM.
|
T11758 |
KI696 isomer
|
1799974-69-8
|
98%
|
|
KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction. KI696 isomer is the less active isomer of KI696 .
|
T11881 |
LSD1-IN-6
|
2035912-43-5
|
98%
|
|
LSD1-IN-6 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1. LSD1-IN-6 is a potent and reversible inhibitor of lysine-specific dem...
|
T7057 |
Methylstat
|
1310877-95-2
|
98%
|
|
Methylstat is a methyl ester prodrug of a Jumonji C domain-containing histone demethylase (JMJD) inhibitor that has favorable cell permeability. The free acid of...
|
T16700 |
QC6352
|
1851373-36-8
|
98%
|
|
QC6352 is a selective and effective KDM4C inhibitor (IC50: 35 nM).
|
T13056 |
T-448 free base
|
1597426-52-2
|
98%
|
|
T-448 free base is a specific, orally active and irreversible lysine-specific demethylase 1 (LSD1, an H3K4 demethylase) inhibitor(IC50 of 22 nM).
|
T11475 |
GSK-J1 lithium salt
|
2309668-29-7
|
98%
|
|
GSK-J1 lithium salt is an effective inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with an IC 50 of 60 nM for KDM6B.
|
T15650 |
KDM5A-IN-1
|
1905481-36-8
|
98%
|
|
KDM5A-IN-1 is a potent and orally bioavailable inhibitor of pan-histone lysine demethylases 5 (IC50s: 45 nM, 56 nM, and 55 nM for KDM5A, KDM5B, and KDM5C) and (E...
|
T13052 |
S2101
|
1239262-36-2
|
98%
|
|
S 2101 is an inhibitor of lysine-specific demethylase 1 (LSD1)(IC50 of 0.99 μM, Ki of 0.61 μM and Kinact/Ki of 4560 M/s).
|
T3677 |
GSK2879552
|
1401966-69-5
|
98%
|
|
GSK2879552 is a selective, orally bioavailable, irreversible, mechanism-based inactivator of lysine-specific demethylase 1 (LSD1)/corepressor, with potential ant...
|
T11755 |
KF 13218
|
127654-03-9
|
98%
|
|
KF 13218 is a selective, potent and long lasting thromboxane B2 (TXB2) synthase inhibitor with an IC50 value of 5.3±1.3 nM.
|
T17278 |
YUKA1
|
708991-09-7
|
98%
|
|
YUKA1 is a potent and cell-permeable Lysine demethylase 5A inhibitor (IC50: 2.66 μM) and less active on KDM5C (IC50, 7.12 μM). YUKA1 is inactive on KDM5B, KDM6A,...
|
T22299 |
CPI-455 HCl
|
2095432-28-1
|
98%
|
|
CPI-455 is a specific KDM5 inhibitor with IC50 value of 10 ± 1 nM for full-length KDM5A in enzymatic assays, elevating global levels of H3K4 trimethylation (H3K...
|
T12701 |
(rel)-Tranylcypromine D5 hydrochloride
|
107077-98-5
|
98%
|
|
(rel)-Tranylcypromine D5 hydrochloride is a deuterium labeled (rel)-Tranylcypromine hydrochloride. (rel)-Tranylcypromine hydrochloride is an irreversible, nonsel...
|
T13057 |
T-448
|
1597426-53-3
|
98%
|
|
T-448 is a specific, orally active and irreversible lysine-specific demethylase 1 (LSD1, an H3K4 demethylase) inhibitor(IC50 of 22 nM).
|
T35338 |
CP2
|
|
98%
|
|
|
T21652 |
RN-1 dihydrochloride
|
1781835-13-9
|
98%
|
|
RN-1 dihydrochloride is an effective and selective irreversible inhibitor of lysine-specific demethylase 1 (LSD1, IC50 = 70 nM).
|