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Novel, cell-permeable inhibitor of protein kinase Mζ (PKMζ), a constitutively active, atypical PKC isozyme involved in LTP maintenance. Selectively blocks PKMζ-induced synaptic potentiation in hippocampal slices in vitro. Reverses late-phase LTP (IC50 = 1

ZIP (SCRAMBLED) Acetate (ZIP (SCRAMBLED) Acetate (908012-18-0 Free Base)) is a scrambled peptide that can be used as a negative control for zeta inhibitory peptide (ZIP).

ZIP acetate is a novel, cell-permeable inhibitor of protein kinase Mζ (PKMζ), a constitutively active, atypical PKC isozyme involved in LTP maintenance. Selectively blocks PKMζ-induced synaptic potentiation in hippocampal slices in vitro. Reverses late-ph

ZIP with a biotin moiety covalently attached

ZIP TFA, a selective peptide inhibitor of PKMζ, is capable of blocking the impairment in morphine-conditioned place preference as induced by injections [1].

ZIP(Scrambled) TFA is a scrambled peptide used as a negative control for zeta inhibitory peptide (ZIP).

ZIP14-IN-1 is a selective inhibitor of ZIP14. It can significantly inhibit the activity of ZIP14, but has no significant effect on ZIP8 (SLC39A8). ZIP14-IN-1 can effectively block the uptake of various divalent metal ions including zinc, iron, manganese and cadmium mediated by ZIP14. Its mechanism of action is to bind to the binding pocket formed at the dimer interface of ZIP14, thereby interfering with the metal ion transport pathway. In addition, ZIP14-IN-1 can reduce the levels of reactive oxygen species (ROS) and lipid peroxidation, alleviate metal-induced cytotoxicity, and can be used in related research on cancer cachexia .

Ziprasidone hydrochloride monohydrate (CP 88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic activity.

Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.

Ziprasidone (Geodon) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.

Hydroxy ziprasidone is an impurity of Ziprasidone, an antipsychotic agent and 5-HT and dopamine receptor antagonist.

Ziprasidone, an antipsychotic agent, functions as a dual antagonist of 5-HT (serotonin) and dopamine receptors. Keto Ziprasidone represents an impurity found within Ziprasidone.

Norjuziphine is a useful organic compound for research related to life sciences and the catalog number is T124294.

Ziprasidone-D8 is deuterium labeled Ziprasidone (TMSM-3388), which is a antagonist of combined 5-HT (serotonin) and dopamine receptor and exhibits potent effects of antipsychotic activity.

Taziprinone has been investigated as an antitussive compound.

Balazipone is a bio-active chemical.

Mazipredone is a water-soluble, long-acting prednisolone derivative used topically for skin conditions & parenterally as a glucocorticoid.

Ziprasidone (CP-88059) mesylate is an orally active 5-HT and dopamine receptor antagonist with affinity for D2, 5-HT2A, and 5-HT1A receptors in rats, exhibiting Ki values of 4.8 nM, 0.42 nM, and 3.4 nM, respectively.

Ziprasidone (CP-88059) mesylate trihydrate is an orally active 5-HT and dopamine receptor antagonist in rats, showing affinity for D2, 5-HT2A, and 5-HT1A receptors with Ki values of 4.8 nM, 0.42 nM, and 3.4 nM, respectively.

Orazipone inhibits cytokine production and histamine release; an NSAID.

Kurzipene D, a potent anticancer agent, induces apoptosis and arrests the HepG2 cell cycle at the S stage. Demonstrating anti-tumor effects in an in vivo zebrafish model, Kurzipene D inhibits tumor proliferation and migration.

Ziprasidone amino acid (Ziprasidone Impurity C), an impurity found in Ziprasidone, functions as a combined 5-HT (serotonin) and dopamine receptor antagonist, demonstrating significant antipsychotic activity [1].

Ziptide, a peptide substrate, is recognized by several serine/threonine protein kinases, such as MAPK activated protein kinase 2 (MAPKAPK2), MAPKAPK3, MAPKAPK5, checkpoint kinase 1 (Chk1), AMP-activated protein kinase (AMPK), and calcium/calmodulin-dependent protein kinase II (CamKII). It serves as a tool in evaluating CamKII activity for the development of inhibitors.

Claziprotamidum (Claziprotamide) acts as a positive allosteric modulator (PAM) for panthothenate kinases 1 and 3 (PanK1 and PanK3).